Activation of the P2X7 receptor induces the rapid shedding of CD23 from human and murine B cells A Pupovac, NJ Geraghty, D Watson, R Sluyter Immunology and cell biology 93 (1), 77-85, 2015 | 42 | 2015 |
The P2X7 receptor antagonist Brilliant Blue G reduces serum human interferon-γ in a humanized mouse model of graft-versus-host disease NJ Geraghty, L Belfiore, D Ly, SR Adhikary, SJ Fuller, W Varikatt, ... Clinical & Experimental Immunology 190 (1), 79-95, 2017 | 39 | 2017 |
Amyotrophic lateral sclerosis: proteins, proteostasis, prions, and promises L McAlary, YL Chew, JS Lum, NJ Geraghty, JJ Yerbury, NR Cashman Frontiers in Cellular Neuroscience 14, 581907, 2020 | 32 | 2020 |
The P2X7 receptor antagonist JNJ-47965567 administered thrice weekly from disease onset does not alter progression of amyotrophic lateral sclerosis in SOD1G93A mice D Ly, A Dongol, P Cuthbertson, TV Guy, NJ Geraghty, RA Sophocleous, ... Purinergic signalling 16 (1), 109-122, 2020 | 26 | 2020 |
Long-term treatment with the P2X7 receptor antagonist Brilliant Blue G reduces liver inflammation in a humanized mouse model of graft-versus-host disease NJ Geraghty, D Watson, R Sluyter Cellular Immunology 336, 12-19, 2019 | 24 | 2019 |
P2X7 receptor in skin biology and diseases N Geraghty, D Watson, S Adhikary, R Sluyter | 24 | 2016 |
Increased P2X7 expression in the gastrointestinal tract and skin in a humanised mouse model of graft-versus-host disease P Cuthbertson, SR Adhikary, NJ Geraghty, TV Guy, A Hadjiashrafi, ... Clinical Science 134 (2), 207-223, 2020 | 23 | 2020 |
Pharmacological blockade of the CD39/CD73 pathway but not adenosine receptors augments disease in a humanized mouse model of graft‐versus‐host disease NJ Geraghty, D Watson, R Sluyter Immunology and Cell Biology 97 (6), 597-610, 2019 | 23 | 2019 |
Altered donor P2X7 activity in human leukocytes correlates with P2RX7 genotype but does not affect the development of graft-versus-host disease in humanised mice SR Adhikary, NJ Geraghty, P Cuthbertson, R Sluyter, D Watson Purinergic Signalling 15, 177-192, 2019 | 20 | 2019 |
P2X7 receptor antagonism increases regulatory T cells and reduces clinical and histological graft-versus-host disease in a humanised mouse model P Cuthbertson, NJ Geraghty, SR Adhikary, S Casolin, D Watson, R Sluyter Clinical Science 135 (3), 495-513, 2021 | 18 | 2021 |
Increased splenic human CD4+: CD8+ T cell ratios, serum human interferon-γ and intestinal human interleukin-17 are associated with clinical graft-versus-host disease in … NJ Geraghty, L Belfiore, SR Adhikary, SI Alexander, R Sluyter, D Watson Transplant Immunology 54, 38-46, 2019 | 17 | 2019 |
Expanding the family of extracellular chaperones: Identification of human plasma proteins with chaperone activity NJ Geraghty, S Satapathy, M Kelly, F Cheng, A Lee, MR Wilson Protein Science 30 (11), 2272-2286, 2021 | 15 | 2021 |
The P2X7 receptor is not essential for development of imiquimod-induced psoriasis-like inflammation in mice NJ Geraghty, KJ Mansfield, SJ Fuller, D Watson, R Sluyter Purinergic Signalling 13, 405-415, 2017 | 15 | 2017 |
Comparison of peripheral blood mononuclear cell isolation techniques and the impact of cryopreservation on human lymphocytes expressing CD39 and CD73 RJ Turner, NJ Geraghty, JG Williams, D Ly, D Brungs, MG Carolan, ... Purinergic Signalling 16 (3), 389-401, 2020 | 14 | 2020 |
Telomere length varies substantially between blood cell types in a reptile M Olsson, NJ Geraghty, E Wapstra, M Wilson Royal Society Open Science 7 (6), 192136, 2020 | 14 | 2020 |
Neuroserpin and transthyretin are extracellular chaperones that preferentially inhibit amyloid formation J West, S Satapathy, DR Whiten, M Kelly, NJ Geraghty, EJ Proctor, ... Science advances 7 (50), eabf7606, 2021 | 13 | 2021 |
The A2A receptor agonist CGS 21680 has beneficial and adverse effects on disease development in a humanised mouse model of graft-versus-host disease NJ Geraghty, SR Adhikary, D Watson, R Sluyter International Immunopharmacology 72, 479-486, 2019 | 13 | 2019 |
Purinergic signalling in allogeneic haematopoietic stem cell transplantation and graft-versus-host disease P Cuthbertson, NJ Geraghty, SR Adhikary, KM Bird, SJ Fuller, D Watson, ... International Journal of Molecular Sciences 22 (15), 8343, 2021 | 10 | 2021 |
Streptococcus pyogenes M1T1 Variants Induce an Inflammatory Neutrophil Phenotype Including Activation of Inflammatory Caspases JG Williams, D Ly, NJ Geraghty, JD McArthur, HKN Vyas, J Gorman, ... Frontiers in Cellular and Infection Microbiology 10, 596023, 2021 | 10 | 2021 |
Humanized mouse model to study the P2X7 receptor in graft-versus-host disease D Watson, SR Adhikary, P Cuthbertson, NJ Geraghty, KM Bird, A Elhage, ... The P2X7 Receptor: Methods and Protocols, 315-340, 2022 | 4 | 2022 |