| On terminal alkynes that can react with active-site cysteine nucleophiles in proteases R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ... Journal of the American Chemical Society 135 (8), 2867-2870, 2013 | 304 | 2013 |
| Revealing promiscuous drug–target interactions by chemical proteomics M Bantscheff, A Scholten, AJR Heck Drug discovery today 14 (21-22), 1021-1029, 2009 | 140 | 2009 |
| Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and … A Scholten, MK Poh, TAB van Veen, B van Breukelen, MA Vos, AJR Heck Journal of proteome research 5 (6), 1435-1447, 2006 | 129 | 2006 |
| Human CD62Ldim neutrophils identified as a separate subset by proteome profiling and in vivo pulse-chase labeling T Tak, P Wijten, M Heeres, P Pickkers, A Scholten, AJR Heck, ... Blood, The Journal of the American Society of Hematology 129 (26), 3476-3485, 2017 | 111 | 2017 |
| Sphingosine kinase interacting protein is an A‐kinase anchoring protein specific for type I cAMP‐dependent protein kinase D Kovanich, MAG van der Heyden, TT Aye, TAB van Veen, AJR Heck, ... Chembiochem 11 (7), 963-971, 2010 | 99 | 2010 |
| cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain V Alverdi, H Mazon, C Versluis, W Hemrika, G Esposito, ... Journal of molecular biology 375 (5), 1380-1393, 2008 | 98 | 2008 |
| High precision platelet releasate definition by quantitative reversed protein profiling—brief report P Wijten, T van Holten, LL Woo, OB Bleijerveld, M Roest, AJR Heck, ... Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1635-1638, 2013 | 95 | 2013 |
| Reorganized PKA-AKAP associations in the failing human heart TT Aye, S Soni, TAB van Veen, MAG van der Heyden, S Cappadona, ... Journal of molecular and cellular cardiology 52 (2), 511-518, 2012 | 92 | 2012 |
| A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane PP Burgers, Y Ma, L Margarucci, M Mackey, MAG van der Heyden, ... Journal of Biological Chemistry 287 (52), 43789-43797, 2012 | 91 | 2012 |
| Protease bias in absolute protein quantitation M Peng, N Taouatas, S Cappadona, B Van Breukelen, S Mohammed, ... Nature methods 9 (6), 524-525, 2012 | 91 | 2012 |
| Applications of stable isotope dimethyl labeling in quantitative proteomics D Kovanich, S Cappadona, R Raijmakers, S Mohammed, A Scholten, ... Analytical and bioanalytical chemistry 404, 991-1009, 2012 | 90 | 2012 |
| SPEG (striated muscle preferentially expressed protein kinase) is essential for cardiac function by regulating junctional membrane complex activity AP Quick, Q Wang, LE Philippen, G Barreto-Torres, DY Chiang, ... Circulation research 120 (1), 110-119, 2017 | 82 | 2017 |
| Proteome-wide protein concentrations in the human heart TT Aye, A Scholten, N Taouatas, A Varro, TAB Van Veen, MA Vos, ... Molecular BioSystems 6 (10), 1917-1927, 2010 | 80 | 2010 |
| Quantitative proteomics analysis reveals similar release profiles following specific PAR-1 or PAR-4 stimulation of platelets TC van Holten, OB Bleijerveld, P Wijten, PG de Groot, AJR Heck, ... Cardiovascular research 103 (1), 140-146, 2014 | 73 | 2014 |
| Diversity of cAMP-dependent protein kinase isoforms and their anchoring proteins in mouse ventricular tissue A Scholten, TAB van Veen, MA Vos, AJR Heck Journal of proteome research 6 (5), 1705-1717, 2007 | 71 | 2007 |
| Selectivity in Enrichment of cAMP-dependent Protein Kinase Regulatory Subunits Type I and Type II and Their Interactors Using Modified cAMP Affinity Resins* S TT Aye, S Mohammed, HWP van den Toorn, TAB van Veen, ... Molecular & Cellular Proteomics 8 (5), 1016-1028, 2009 | 57 | 2009 |
| Interrogating cAMP-dependent kinase signaling in Jurkat T cells via a protein kinase A targeted immune-precipitation phosphoproteomics approach P Giansanti, MP Stokes, JC Silva, A Scholten, AJR Heck Molecular & Cellular Proteomics 12 (11), 3350-3359, 2013 | 48 | 2013 |
| Identification of enriched PTM crosstalk motifs from large-scale experimental data sets M Peng, A Scholten, AJR Heck, B van Breukelen Journal of proteome research 13 (1), 249-259, 2014 | 44 | 2014 |
| Surface‐Plasmon‐Resonance‐Based Chemical Proteomics: Efficient Specific Extraction and Semiquantitative Identification of Cyclic Nucleotide‐Binding Proteins from Cellular … NFC Visser, A Scholten, RHH van den Heuvel, AJR Heck ChemBioChem 8 (3), 298-305, 2007 | 44 | 2007 |
| Analysis of protein-protein interaction surfaces using a combination of efficient lysine acetylation and nanoLC-MALDI-MS/MS applied to the E9: Im9 bacteriotoxin—immunity … A Scholten, NFC Visser, RHH van den Heuvel, AJR Heck Journal of the American Society for Mass Spectrometry 17, 983-994, 2006 | 38 | 2006 |
Albert J. R. HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht UniversityVerified email at uu.nl
