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| Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease C Cruchaga, CM Karch, SC Jin, BA Benitez, Y Cai, R Guerreiro, O Harari, ... Nature 505 (7484), 550-554, 2014 | 524 | 2014 |
| Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 ( CHRM2 ) gene with alcohol dependence … JC Wang, AL Hinrichs, H Stock, J Budde, R Allen, S Bertelsen, JM Kwon, ... Human molecular genetics 13 (17), 1903-1911, 2004 | 379 | 2004 |
| A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 344 | 2017 |
| A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 344 | 2017 |
| The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans NL Saccone, JC Wang, N Breslau, EO Johnson, D Hatsukami, ... Cancer research 69 (17), 6848-6856, 2009 | 306 | 2009 |
| An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations U Dube, JL Del-Aguila, Z Li, JP Budde, S Jiang, S Hsu, L Ibanez, ... Nature neuroscience 22 (11), 1903-1912, 2019 | 260 | 2019 |
| Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence JC Wang, R Grucza, C Cruchaga, AL Hinrichs, S Bertelsen, JP Budde, ... Molecular psychiatry 14 (5), 501-510, 2009 | 256 | 2009 |
| HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin‐positive, tau‐negative inclusions caused by a missense mutation in the signal peptide of progranulin O Mukherjee, P Pastor, NJ Cairns, S Chakraverty, JSK Kauwe, S Shears, ... Annals of Neurology: Official Journal of the American Neurological …, 2006 | 219 | 2006 |
| Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5 JC Wang, C Cruchaga, NL Saccone, S Bertelsen, P Liu, JP Budde, ... Human molecular genetics 18 (16), 3125-3135, 2009 | 211 | 2009 |
| The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 208 | 2019 |
| Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers Y Deming, Z Li, M Kapoor, O Harari, JL Del-Aguila, K Black, D Carrell, ... Acta neuropathologica 133 (5), 839-856, 2017 | 200 | 2017 |
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| Using dimensional models of externalizing psychopathology to aid in gene identification DM Dick, F Aliev, JC Wang, RA Grucza, M Schuckit, S Kuperman, ... Archives of general psychiatry 65 (3), 310-318, 2008 | 177 | 2008 |
| A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence RA Grucza, JC Wang, JA Stitzel, AL Hinrichs, SF Saccone, NL Saccone, ... Biological psychiatry 64 (11), 922-929, 2008 | 166 | 2008 |
| Family‐Based Association Analyses of Alcohol Dependence Phenotypes Across DRD2 and Neighboring Gene ANKK1 DM Dick, JC Wang, J Plunkett, F Aliev, A Hinrichs, S Bertelsen, JP Budde, ... Alcoholism: Clinical and Experimental Research 31 (10), 1645-1653, 2007 | 166 | 2007 |
| Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence AL Hinrichs, JC Wang, B Bufe, JM Kwon, J Budde, R Allen, S Bertelsen, ... The American Journal of Human Genetics 78 (1), 103-111, 2006 | 157 | 2006 |
| A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain JL Del-Aguila, Z Li, U Dube, KA Mihindukulasuriya, JP Budde, ... Alzheimer's research & therapy 11, 1-16, 2019 | 154 | 2019 |
