| Ligand-directed tosyl chemistry for protein labeling in vivo S Tsukiji, M Miyagawa, Y Takaoka, T Tamura, I Hamachi Nature chemical biology 5 (5), 341-343, 2009 | 380 | 2009 |
| Chemistry for covalent modification of endogenous/native proteins: from test tubes to complex biological systems T Tamura, I Hamachi Journal of the American Chemical Society 141 (7), 2782-2799, 2018 | 271 | 2018 |
| Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide T Tamura, T Ueda, T Goto, T Tsukidate, Y Shapira, Y Nishikawa, ... Nature Communications 9 (1), 1870, 2018 | 158 | 2018 |
| Recent progress in design of protein-based fluorescent biosensors and their cellular applications T Tamura, I Hamachi ACS chemical biology 9 (12), 2708-2717, 2014 | 121 | 2014 |
| Selective and reversible modification of kinase cysteines with chlorofluoroacetamides N Shindo, H Fuchida, M Sato, K Watari, T Shibata, K Kuwata, C Miura, ... Nature Chemical Biology 15 (3), 250-258, 2019 | 105 | 2019 |
| Native FKBP12 engineering by ligand-directed tosyl chemistry: labeling properties and application to photo-cross-linking of protein complexes in vitro and in living cells T Tamura, S Tsukiji, I Hamachi Journal of the American Chemical Society 134 (4), 2216-2226, 2012 | 105 | 2012 |
| Quenched ligand-directed tosylate reagents for one-step construction of turn-on fluorescent biosensors S Tsukiji, H Wang, M Miyagawa, T Tamura, Y Takaoka, I Hamachi Journal of the American Chemical Society 131 (25), 9046-9054, 2009 | 97 | 2009 |
| Chemical tools for endogenous protein labeling and profiling K Shiraiwa, R Cheng, H Nonaka, T Tamura, I Hamachi Cell Chemical Biology 27 (8), 970-985, 2020 | 80 | 2020 |
| Fluorophore labeling of native FKBP12 by ligand-directed tosyl chemistry allows detection of its molecular interactions in vitro and in living cells T Tamura, Y Kioi, T Miki, S Tsukiji, I Hamachi Journal of the American Chemical Society 135 (18), 6782-6785, 2013 | 76 | 2013 |
| A set of organelle-localizable reactive molecules for mitochondrial chemical proteomics in living cells and brain tissues Y Yasueda, T Tamura, A Fujisawa, K Kuwata, S Tsukiji, S Kiyonaka, ... Journal of the American Chemical Society 138 (24), 7592-7602, 2016 | 63 | 2016 |
| Analysis of cell-surface receptor dynamics through covalent labeling by catalyst-tethered antibody T Hayashi, Y Yasueda, T Tamura, Y Takaoka, I Hamachi Journal of the American Chemical Society 137 (16), 5372-5380, 2015 | 61 | 2015 |
| Organelle membrane-specific chemical labeling and dynamic imaging in living cells T Tamura, A Fujisawa, M Tsuchiya, Y Shen, K Nagao, S Kawano, ... Nature Chemical Biology 16 (12), 1361-1367, 2020 | 58 | 2020 |
| Affinity-guided oxime chemistry for selective protein acylation in live tissue systems T Tamura, Z Song, K Amaike, S Lee, S Yin, S Kiyonaka, I Hamachi Journal of the American Chemical Society 139 (40), 14181-14191, 2017 | 58 | 2017 |
| Semisynthetic lectin–4-dimethylaminopyridine conjugates for labeling and profiling glycoproteins on live cell surfaces T Hayashi, Y Sun, T Tamura, K Kuwata, Z Song, Y Takaoka, I Hamachi Journal of the American Chemical Society 135 (33), 12252-12258, 2013 | 50 | 2013 |
| Recognition-driven chemical labeling of endogenous proteins in multi-molecular crowding in live cells K Amaike, T Tamura, I Hamachi Chemical communications 53 (88), 11972-11983, 2017 | 49 | 2017 |
| Enhanced Suppression of a Protein–Protein Interaction in Cells Using Small-Molecule Covalent Inhibitors Based on an N-Acyl-N-alkyl Sulfonamide Warhead T Ueda, T Tamura, M Kawano, K Shiono, F Hobor, AJ Wilson, I Hamachi Journal of the American Chemical Society 143 (12), 4766-4774, 2021 | 46 | 2021 |
| Development of a photoactivatable proximity labeling method for the identification of nuclear proteins T Tamura, M Takato, K Shiono, I Hamachi Chemistry letters 49 (2), 145-148, 2020 | 39 | 2020 |
| Chemical profiling of the endoplasmic reticulum proteome using designer labeling reagents A Fujisawa, T Tamura, Y Yasueda, K Kuwata, I Hamachi Journal of the American Chemical Society 140 (49), 17060-17070, 2018 | 37 | 2018 |
| Imaging and profiling of proteins under oxidative conditions in cells and tissues by hydrogen-peroxide-responsive labeling H Zhu, T Tamura, A Fujisawa, Y Nishikawa, R Cheng, M Takato, ... Journal of the American Chemical Society 142 (37), 15711-15721, 2020 | 36 | 2020 |
| Chemical proteomics for subcellular proteome analysis H Zhu, T Tamura, I Hamachi Current Opinion in Chemical Biology 48, 1-7, 2019 | 31 | 2019 |
