Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect M Chattopadhyay, R Kodela, N Nath, YM Dastagirzada, ... Biochemical pharmacology 83 (6), 715-722, 2012 | 153 | 2012 |
NOSH-aspirin (NBS-1120), a novel nitric oxide-and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with … R Kodela, M Chattopadhyay, CA Velázquez-Martínez, K Kashfi Biochemical pharmacology 98 (4), 564-572, 2015 | 78 | 2015 |
Synthesis and chemical and biological comparison of nitroxyl-and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives D Basudhar, G Bharadwaj, RY Cheng, S Jain, S Shi, JL Heinecke, ... Journal of medicinal chemistry 56 (20), 7804-7820, 2013 | 74 | 2013 |
Differential eNOS-signalling by platelet subpopulations regulates adhesion and aggregation A Radziwon-Balicka, G Lesyk, V Back, T Fong, EL Loredo-Calderon, ... Cardiovascular research 113 (14), 1719-1731, 2017 | 70 | 2017 |
Synthesis and biological evaluation of isoxazolo [4, 5-d] pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents K Özadalı, F Özkanlı, S Jain, PPN Rao, CA Velázquez-Martínez Bioorganic & medicinal chemistry 20 (9), 2912-2922, 2012 | 60 | 2012 |
Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents FS Aldawsari, R Aguayo-Ortiz, K Kapilashrami, J Yoo, M Luo, ... Journal of enzyme inhibition and medicinal chemistry 31 (5), 695-703, 2016 | 50 | 2016 |
Pimozide alleviates hyperglycemia in diet-induced obesity by inhibiting skeletal muscle ketone oxidation R Al Batran, K Gopal, ME Capozzi, JJ Chahade, B Saleme, ... Cell Metabolism 31 (5), 909-919. e8, 2020 | 47 | 2020 |
3,4′,5-trans-Trimethoxystilbene; a natural analogue of resveratrol with enhanced anticancer potency FS Aldawsari, CA Velázquez-Martínez Investigational new drugs 33, 775-786, 2015 | 42 | 2015 |
Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-κB signaling R Kodela, N Nath, M Chattopadhyay, DE Nesbitt, CA Velázquez-Martínez, ... Drug design, development and therapy, 4873-4882, 2015 | 39 | 2015 |
Hydrogen sulfide-releasing aspirin modulates xenobiotic metabolizing enzymes in vitro and in vivo M Chattopadhyay, R Kodela, N Nath, CR Street, CA Velázquez-Martínez, ... Biochemical Pharmacology 83 (6), 733-740, 2012 | 35 | 2012 |
Anti-inflammatory and antioxidant properties of a novel resveratrol–salicylate hybrid analog FS Aldawsari, RP Aguiar, LAM Wiirzler, R Aguayo-Ortiz, N Aljuhani, ... Bioorganic & Medicinal Chemistry Letters 26 (5), 1411-1415, 2016 | 33 | 2016 |
Synergistic effects of anethole and ibuprofen in acute inflammatory response ES Wisniewski-Rebecca, BA Rocha, LAM Wiirzler, RKN Cuman, ... Chemico-Biological Interactions 242, 247-253, 2015 | 30 | 2015 |
Untying the knot of transcription factor druggability: Molecular modeling study of FOXM1 inhibitors SA Tabatabaei-Dakhili, R Aguayo-Ortiz, L Domínguez, ... Journal of Molecular Graphics and Modelling 80, 197-210, 2018 | 29 | 2018 |
NSAIDs do not require the presence of a carboxylic acid to exert their anti-inflammatory effect–why do we keep using it? N Ullah, Z Huang, F Sanaee, A Rodriguez-Dimitrescu, F Aldawsari, ... Journal of enzyme inhibition and medicinal chemistry 31 (6), 1018-1028, 2016 | 29 | 2016 |
Targeting of the FOXM1 oncoprotein by E3 ligase-assisted degradation G Luo, X Lin, A Vega-Medina, M Xiao, G Li, H Wei, ... Journal of Medicinal Chemistry 64 (23), 17098-17114, 2021 | 25 | 2021 |
Identification and characterization of novel receptor-interacting serine/threonine‐protein kinase 2 inhibitors using structural similarity analysis M Salla, R Aguayo-Ortiz, GI Danmaliki, A Zare, A Said, J Moore, V Pandya, ... Journal of Pharmacology and Experimental Therapeutics 365 (2), 354-367, 2018 | 25 | 2018 |
Effects of nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NONO-NSAIDs) on melanoma cell adhesion H Cheng, MY Mollica, SH Lee, L Wang, CA Velázquez-Martínez, S Wu Toxicology and applied pharmacology 264 (2), 161-166, 2012 | 25 | 2012 |
Resveratrol and resveratrol-aspirin hybrid compounds as potent intestinal anti-inflammatory and anti-tumor drugs M Salla, V Pandya, KS Bhullar, E Kerek, YF Wong, R Losch, J Ou, ... Molecules 25 (17), 3849, 2020 | 22 | 2020 |
A structure-activity relationship study of Forkhead Domain Inhibitors (FDI): The importance of halogen binding interactions SAT Dakhili, DJ Perez, K Gopal, SYT Dakhili, JR Ussher, ... Bioorganic Chemistry 93, 103269, 2019 | 20 | 2019 |
SP1-independent inhibition of FOXM1 by modified thiazolidinediones SAT Dakhili, DJ Pérez, K Gopal, M Haque, JR Ussher, K Kashfi, ... European Journal of Medicinal Chemistry 209, 112902, 2021 | 19 | 2021 |