Christopher Hale
Christopher Hale
Amgen Research
Verified email at
Cited by
Cited by
A perinuclear actin cap regulates nuclear shape
SB Khatau, CM Hale, PJ Stewart-Hutchinson, MS Patel, CL Stewart, ...
Proceedings of the National Academy of Sciences 106 (45), 19017-19022, 2009
Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration
JSH Lee, CM Hale, P Panorchan, SB Khatau, JP George, Y Tseng, ...
Biophysical journal 93 (7), 2542-2552, 2007
Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness
PJ Stewart-Hutchinson, CM Hale, D Wirtz, D Hodzic
Experimental cell research 314 (8), 1892-1905, 2008
Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models
CM Hale, AL Shrestha, SB Khatau, PJ Stewart-Hutchinson, L Hernandez, ...
Biophysical journal 95 (11), 5462-5475, 2008
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration
SB Khatau, RJ Bloom, S Bajpai, D Razafsky, S Zang, A Giri, PH Wu, ...
Scientific reports 2 (1), 488, 2012
Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow
JSH Lee, P Panorchan, CM Hale, SB Khatau, TP Kole, Y Tseng, D Wirtz
Journal of cell science 119 (9), 1760-1768, 2006
The perinuclear actin cap in health and disease
SB Khatau, DH Kim, CM Hale, RJ Bloom, D Wirtz
Nucleus 1 (4), 337-342, 2010
Resolving the role of actoymyosin contractility in cell microrheology
CM Hale, SX Sun, D Wirtz
PloS one 4 (9), e7054, 2009
High-throughput ballistic injection nanorheology to measure cell mechanics
PH Wu, CM Hale, WC Chen, JSH Lee, Y Tseng, D Wirtz
Nature protocols 7 (1), 155-170, 2012
Magnetic manipulation of nanorods in the nucleus of living cells
A Celedon, CM Hale, D Wirtz
Biophysical journal 101 (8), 1880-1886, 2011
Identification of modulators of autophagic flux in an image-based high content siRNA screen
CM Hale, Q Cheng, D Ortuno, M Huang, D Nojima, PD Kassner, S Wang, ...
Autophagy 12 (4), 713-726, 2016
SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization
CM Hale, WC Chen, SB Khatau, BR Daniels, JSH Lee, D Wirtz
Journal of cell science 124 (24), 4267-4285, 2011
Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells
BR Daniels, CM Hale, SB Khatau, S Kusuma, TM Dobrowsky, S Gerecht, ...
Biophysical journal 99 (11), 3563-3570, 2010
Parallel Fourier ptychographic microscopy for high-throughput screening with 96 cameras (96 Eyes)
ACS Chan, J Kim, A Pan, H Xu, D Nojima, C Hale, S Wang, C Yang
Scientific reports 9 (1), 11114, 2019
Functional arrays of human pluripotent stem cell-derived cardiac microtissues
N Thavandiran, C Hale, P Blit, ML Sandberg, ME McElvain, M Gagliardi, ...
Scientific reports 10 (1), 6919, 2020
Pooled screens identify GPR108 and TM9SF2 as host cell factors critical for AAV transduction
WH Meisen, ZB Nejad, M Hardy, H Zhao, O Oliverio, S Wang, C Hale, ...
Molecular Therapy-Methods & Clinical Development 17, 601-611, 2020
Particle tracking microrheology of cancer cells in living subjects
PH Wu, SS Gambhir, CM Hale, WC Chen, D Wirtz, BR Smith
Materials Today 39, 98-109, 2020
Novel small-molecule troponin activator increases cardiac contractile function without negative impact on energetics
H He, T Baka, J Balschi, AS Motani, KK Nguyen, Q Liu, R Slater, B Rock, ...
Circulation: Heart Failure 15 (3), e009195, 2022
Edited course of biomedical research: leaping forward with CRISPR
PJ Collins, CM Hale, H Xu
Pharmacological research 125, 258-265, 2017
Cellular analysis using label-free parallel array microscopy with Fourier ptychography
DL Wakefield, R Graham, K Wong, S Wang, C Hale, CC Yu
Biomedical Optics Express 13 (3), 1312-1327, 2022
The system can't perform the operation now. Try again later.
Articles 1–20