Secreted factors from brain endothelial cells maintain glioblastoma stem‐like cell expansion through the mTOR pathway EM Galan‐Moya, A Le Guelte, E Lima‐Fernandes, C Thirant, J Dwyer, ... EMBO reports 12 (5), 470-476, 2011 | 150 | 2011 |
P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance MA De la Cruz-Morcillo, MLL Valero, JL Callejas-Valera, ... Oncogene 31 (9), 1073-1085, 2012 | 135 | 2012 |
Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma L Treps, S Edmond, E Harford-Wright, EM Galan-Moya, A Schmitt, S Azzi, ... Oncogene 35 (20), 2615-2623, 2016 | 123 | 2016 |
Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2 J Dwyer, JK Hebda, A Le Guelte, EM Galan-Moya, SS Smith, S Azzi, ... Public Library of Science 7 (9), e45562, 2012 | 115 | 2012 |
Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor C Thirant, EM Galan‐Moya, LG Dubois, S Pinte, P Chafey, C Broussard, ... Stem cells 30 (5), 845-853, 2012 | 106 | 2012 |
Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer MM Noblejas-López, C Nieto-Jimenez, M Burgos, M Gómez-Juárez, ... Journal of Experimental & Clinical Cancer Research 38, 1-9, 2019 | 83 | 2019 |
Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation A Le Guelte, EM Galan-Moya, J Dwyer, L Treps, G Kettler, JK Hebda, ... Journal of cell Science 125 (17), 4137-4146, 2012 | 82 | 2012 |
ERK2, but Not ERK1, Mediates Acquired and “De novo” Resistance to Imatinib Mesylate: Implication for CML Therapy CI Aceves-Luquero, A Agarwal, JL Callejas-Valera, L Arias-González, ... PloS one 4 (7), e6124, 2009 | 54 | 2009 |
Balance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLC EM Galan-Moya, MA de la Cruz-Morcillo, ML Valero, JL Callejas-Valera, ... PloS one 6 (12), e28406, 2011 | 52 | 2011 |
Use of compounds inhibiting apelin / apj / gp130 signaling for treating cancer J Gavard, EM Galan-Moya WO Patent WO/2015/140,296, 2015 | 48* | 2015 |
Synthetic lethality interaction between aurora kinases and CHEK1 inhibitors in ovarian cancer A Alcaraz-Sanabria, C Nieto-Jimenez, V Corrales-Sanchez, ... Molecular cancer therapeutics 16 (11), 2552-2562, 2017 | 47 | 2017 |
PAKing up to the endothelium EMG Moya, A Le Guelte, J Gavard Cellular signalling 21 (12), 1727-1737, 2009 | 46 | 2009 |
Functional transcriptomic annotation and protein–protein interaction network analysis identify NEK2, BIRC5, and TOP2A as potential targets in obese patients with luminal A … M Nuncia-Cantarero, S Martinez-Canales, F Andrés-Pretel, G Santpere, ... Breast cancer research and treatment 168, 613-623, 2018 | 42 | 2018 |
Expression of MHC class I, HLA-A and HLA-B identifies immune-activated breast tumors with favorable outcome MDM Noblejas-López, C Nieto-Jiménez, S Morcillo Garcia, J Pérez-Peña, ... Oncoimmunology 8 (10), e1629780, 2019 | 41 | 2019 |
c‐Abl activates p38 MAPK independently of its tyrosine kinase activity: Implications in cisplatin‐based therapy EM Galan‐Moya, J Hernandez‐Losa, CI Aceves Luquero, ... International journal of cancer 122 (2), 289-297, 2008 | 40 | 2008 |
Trastuzumab-targeted biodegradable nanoparticles for enhanced delivery of dasatinib in HER2+ metastasic breast cancer E Niza, MM Noblejas-López, I Bravo, C Nieto-Jiménez, JA Castro-Osma, ... Nanomaterials 9 (12), 1793, 2019 | 39 | 2019 |
Remodeling of VE-cadherin junctions by the human herpes virus 8 G-protein coupled receptor J Dwyer, A Le Guelte, EM Galan Moya, M Sumbal, A Carlotti, L Douguet, ... Oncogene 30 (2), 190-200, 2011 | 37 | 2011 |
Transcriptomic immunologic signature associated with favorable clinical outcome in basal-like breast tumors S Martinez-Canales, F Cifuentes, M López De Rodas Gregorio, ... PloS one 12 (5), e0175128, 2017 | 31 | 2017 |
Modulation of the p38 MAPK (mitogen-activated protein kinase) pathway through Bcr/Abl: implications in the cellular response to Ara-C VJ Sanchez-arevalo lobo, CI Aceves luquero, L Alvarez-Vallina, ... Biochemical Journal 387 (1), 231-238, 2005 | 27 | 2005 |
E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in vH-Ras-induced senescence JL Callejas-Valera, J Guinea-Viniegra, C Ramírez-Castillejo, JA Recio, ... Journal of biological chemistry 283 (19), 13450-13458, 2008 | 25 | 2008 |