| Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity T Anastassiadis, SW Deacon, K Devarajan, H Ma, JR Peterson Nature biotechnology 29 (11), 1039-1045, 2011 | 969 | 2011 |
| An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase SW Deacon, A Beeser, JA Fukui, UEE Rennefahrt, C Myers, J Chernoff, ... Chemistry & biology 15 (4), 322-331, 2008 | 441 | 2008 |
| Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton JR Peterson, TJ Mitchison Chemistry & biology 9 (12), 1275-1285, 2002 | 408 | 2002 |
| Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins. JR Peterson, A Ora, PN Van, A Helenius Molecular biology of the cell 6 (9), 1173-1184, 1995 | 372 | 1995 |
| Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities PL Earl, CC Broder, D Long, SA Lee, J Peterson, S Chakrabarti, ... Journal of virology 68 (5), 3015-3026, 1994 | 297 | 1994 |
| Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation JR Peterson, LC Bickford, D Morgan, AS Kim, O Ouerfelli, MW Kirschner, ... Nature structural & molecular biology 11 (8), 747-755, 2004 | 217 | 2004 |
| Resistance to BET bromodomain inhibitors is mediated by kinome reprogramming in ovarian cancer AM Kurimchak, C Shelton, KE Duncan, KJ Johnson, J Brown, S O’Brien, ... Cell reports 16 (5), 1273-1286, 2016 | 210 | 2016 |
| Conformational analysis of the DFG-out kinase motif and biochemical profiling of structurally validated type II inhibitors RSK Vijayan, P He, V Modi, KC Duong-Ly, H Ma, JR Peterson, ... Journal of medicinal chemistry 58 (1), 466-479, 2015 | 207 | 2015 |
| Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro HE Pelish, JR Peterson, SB Salvarezza, E Rodriguez-Boulan, JL Chen, ... Nature chemical biology 2 (1), 39-46, 2006 | 195 | 2006 |
| Specificity profiling of Pak kinases allows identification of novel phosphorylation sites UEE Rennefahrt, SW Deacon, SA Parker, K Devarajan, A Beeser, ... Journal of Biological Chemistry 282 (21), 15667-15678, 2007 | 154 | 2007 |
| Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs J Eswaran, WH Lee, JÉ Debreczeni, P Filippakopoulos, A Turnbull, ... Structure 15 (2), 201-213, 2007 | 143 | 2007 |
| An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently J Viaud, JR Peterson Molecular cancer therapeutics 8 (9), 2559-2565, 2009 | 142 | 2009 |
| The human kinome and kinase inhibition KC Duong‐Ly, JR Peterson Current protocols in pharmacology 60 (1), 2.9. 1-2.9. 14, 2013 | 128 | 2013 |
| Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1 A Beatty, T Singh, YY Tyurina, VA Tyurin, S Samovich, E Nicolas, ... Nature communications 12 (1), 2244, 2021 | 126 | 2021 |
| Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration VD Delorme-Walker, JR Peterson, J Chernoff, CM Waterman, G Danuser, ... Journal of Cell Biology 193 (7), 1289-1303, 2011 | 112 | 2011 |
| Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis I Malyukova, KF Murray, C Zhu, E Boedeker, A Kane, K Patterson, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 296 (1 …, 2009 | 111 | 2009 |
| A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions JR Peterson, RS Lokey, TJ Mitchison, MW Kirschner Proceedings of the National Academy of Sciences 98 (19), 10624-10629, 2001 | 106 | 2001 |
| Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity C Chen, BH Ha, AF Thévenin, HJ Lou, R Zhang, KY Yip, JR Peterson, ... Molecular cell 53 (1), 140-147, 2014 | 103 | 2014 |
| Calnexin, calreticulin, and Bip/Kar2p in protein folding DN Hebert, JF Simons, JR Peterson, A Helenius Cold Spring Harbor symposia on quantitative biology 60, 405-415, 1995 | 94 | 1995 |
| Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components JR Peterson, AM Lebensohn, HE Pelish, MW Kirschner Chemistry & biology 13 (4), 443-452, 2006 | 82 | 2006 |
