Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines SJ Kattman, AD Witty, M Gagliardi, NC Dubois, M Niapour, A Hotta, J Ellis, ... Cell stem cell 8 (2), 228-240, 2011 | 1385 | 2011 |
SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells NC Dubois, AM Craft, P Sharma, DA Elliott, EG Stanley, AG Elefanty, ... Nature biotechnology 29 (11), 1011-1018, 2011 | 629 | 2011 |
Design and formulation of functional pluripotent stem cell-derived cardiac microtissues N Thavandiran, N Dubois, A Mikryukov, S Massé, B Beca, CA Simmons, ... Proceedings of the National Academy of Sciences 110 (49), E4698-E4707, 2013 | 319 | 2013 |
Nestin‐Cre transgenic mouse line Nes‐Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite‐derived tissues NC Dubois, D Hofmann, K Kaloulis, JM Bishop, A Trumpp genesis 44 (8), 355-360, 2006 | 206 | 2006 |
Genome-nuclear lamina interactions regulate cardiac stem cell lineage restriction A Poleshko, PP Shah, M Gupta, A Babu, MP Morley, LJ Manderfield, ... Cell 171 (3), 573-587. e14, 2017 | 197 | 2017 |
c-Myc is required for the formation of intestinal crypts but dispensable for homeostasis of the adult intestinal epithelium MD Bettess, N Dubois, MJ Murphy, C Dubey, C Roger, S Robine, ... Molecular and cellular biology 25 (17), 7868-7878, 2005 | 187 | 2005 |
Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation V Marsh, DJ Winton, GT Williams, N Dubois, A Trumpp, OJ Sansom, ... Nature genetics 40 (12), 1436-1444, 2008 | 127 | 2008 |
Optimizing cardiac delivery of modified mRNA N Sultana, A Magadum, Y Hadas, J Kondrat, N Singh, E Youssef, ... Molecular therapy 25 (6), 1306-1315, 2017 | 122 | 2017 |
Altering sphingolipid metabolism attenuates cell death and inflammatory response after myocardial infarction Y Hadas, AS Vincek, E Youssef, MM Żak, E Chepurko, N Sultana, ... Circulation 141 (11), 916-930, 2020 | 116 | 2020 |
Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function NC Dubois, C Adolphe, A Ehninger, RA Wang, EJ Robertson, A Trumpp Oxford University Press for The Company of Biologists Limited 135 (14), 2455 …, 2008 | 113 | 2008 |
Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene T Oskarsson, MAG Essers, N Dubois, S Offner, C Dubey, C Roger, ... Genes & development 20 (15), 2024-2029, 2006 | 104 | 2006 |
Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential E Bardot, D Calderon, F Santoriello, S Han, K Cheung, B Jadhav, ... Nature communications 8 (1), 14428, 2017 | 100 | 2017 |
Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair A Magadum, Y Ding, L He, T Kim, MD Vasudevarao, Q Long, K Yang, ... Cell research 27 (8), 1002-1019, 2017 | 77 | 2017 |
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, ... Nature medicine 22 (12), 1421-1427, 2016 | 65 | 2016 |
Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression R Josowitz, J Lu, C Falce, SL D’Souza, M Wu, N Cohen, NC Dubois, ... PLoS One 9 (7), e101316, 2014 | 62 | 2014 |
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes NM Wickramasinghe, D Sachs, B Shewale, DM Gonzalez, ... Cell Stem Cell 29 (4), 559-576. e7, 2022 | 55 | 2022 |
The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation HD Beer, C Munding, N Dubois, C Mamie, D Hohl, S Werner Journal of Biological Chemistry 277 (23), 20740-20749, 2002 | 47 | 2002 |
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function P Sharma, C Abbasi, S Lazic, ACT Teng, D Wang, N Dubois, ... Nature Communications 6 (1), 8391, 2015 | 44 | 2015 |
Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells O El-Mounayri, A Mihic, EA Shikatani, M Gagliardi, SK Steinbach, ... Cardiovascular research 98 (1), 125-135, 2013 | 37 | 2013 |
An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype PP Shah, KC Keough, K Gjoni, GT Santini, RJ Abdill, NM Wickramasinghe, ... Genome biology 24 (1), 16, 2023 | 30 | 2023 |