Clonal evolution in breast cancer revealed by single nucleus genome sequencing Y Wang, J Waters, ML Leung, A Unruh, W Roh, X Shi, K Chen, P Scheet, ... Nature 512 (7513), 155-160, 2014 | 1142 | 2014 |
Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade PL Chen, W Roh, A Reuben, ZA Cooper, CN Spencer, PA Prieto, JP Miller, ... Cancer discovery 6 (8), 827-837, 2016 | 927 | 2016 |
Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance W Roh, PL Chen, A Reuben, CN Spencer, PA Prieto, JP Miller, ... Science translational medicine 9 (379), eaah3560, 2017 | 760 | 2017 |
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade MC Andrews, CPM Duong, V Gopalakrishnan, V Iebba, WS Chen, ... Nature medicine 27 (8), 1432-1441, 2021 | 254 | 2021 |
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma A Reuben, CN Spencer, PA Prieto, V Gopalakrishnan, SM Reddy, ... NPJ genomic medicine 2 (1), 10, 2017 | 131 | 2017 |
The lipogenic regulator SREBP2 induces transferrin in circulating melanoma cells and suppresses ferroptosis X Hong, W Roh, RJ Sullivan, KHK Wong, BS Wittner, H Guo, TD Dubash, ... Cancer discovery 11 (3), 678-695, 2021 | 129 | 2021 |
The natural anticancer agent plumbagin induces potent cytotoxicity in MCF-7 human breast cancer cells by inhibiting a PI-5 kinase for ROS generation JH Lee, JH Yeon, H Kim, W Roh, J Chae, HO Park, DM Kim Public Library of Science 7 (9), e45023, 2012 | 90 | 2012 |
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers R Bill, P Wirapati, M Messemaker, W Roh, B Zitti, F Duval, M Kiss, JC Park, ... Science 381 (6657), 515-524, 2023 | 68 | 2023 |
A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 … G Romano, PL Chen, P Song, JL McQuade, RJ Liang, M Liu, W Roh, ... Cancer discovery 8 (5), 556-567, 2018 | 59 | 2018 |
Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity WC Lee, A Reuben, X Hu, N McGranahan, R Chen, A Jalali, MV Negrao, ... Genome biology 21, 1-21, 2020 | 41 | 2020 |
Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma A Mitra, MC Andrews, W Roh, MP De Macedo, CW Hudgens, F Carapeto, ... Nature communications 11 (1), 1839, 2020 | 22 | 2020 |
Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer N Vidula, T Dubash, MS Lawrence, A Simoneau, A Niemierko, E Blouch, ... Clinical Cancer Research 26 (18), 4852-4862, 2020 | 14 | 2020 |
High-resolution profiling of lung adenocarcinoma identifies expression subtypes with specific biomarkers and clinically relevant vulnerabilities W Roh, Y Geffen, H Cha, M Miller, S Anand, J Kim, DI Heiman, JF Gainor, ... Cancer research 82 (21), 3917-3931, 2022 | 13 | 2022 |
External compression-induced fracture patterning on the surface of poly (dimethylsiloxane) cubes and microspheres T Uchida, KL Mills, CH Kuo, W Roh, YC Tung, AL Garner, K Koide, ... Langmuir 25 (5), 3102-3107, 2009 | 8 | 2009 |
Clonal evolution of acute myeloid leukemia relapsed after 19 years of remission K Takahashi, W Roh, J Zhang, A Propotopov, K Patel, S Strickland, A Kim, ... American journal of hematology 90 (7), E134, 2015 | 7 | 2015 |
Molecular and immune heterogeneity in synchronous melanoma metastases A Reuben, C Spencer, J Roszik, J Miller, L Kwong, H Jiang, C Haymaker, ... Journal for immunotherapy of cancer 3, 1-1, 2015 | 5 | 2015 |
Glasdegib plus intensive or non-intensive chemotherapy for untreated acute myeloid leukemia: results from the randomized, phase 3 BRIGHT AML 1019 trial MA Sekeres, P Montesinos, J Novak, J Wang, D Jeyakumar, B Tomlinson, ... Leukemia 37 (10), 2017-2026, 2023 | 4 | 2023 |
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade J Wargo, M Andrews, C Duong, V Gopalakrishnan, V Iebba, WS Chen, ... | 2 | 2020 |
Comprehensive molecular profiling of primary tumors and paired distant metastases in non-small cell lung cancer WC Lee, D Gomez, J Zhang, A Reuben, A Jalali, W Roh, CC Wu, W Lu, ... Cancer Research 79 (13_Supplement), 2741-2741, 2019 | 1 | 2019 |
Multi-spatial whole-lesion molecular heterogeneity of an immunotherapy-resistant metastatic melanoma. A Mitra, W Roh, A Reuben, M Macedo, FCL Carapeto, C Gumbs, J Zhang, ... Journal of Clinical Oncology 36 (15_suppl), 9568-9568, 2018 | 1 | 2018 |