Konstantinos Konstantopoulos
Konstantinos Konstantopoulos
William H. Schwarz Professor of Chemical and Biomolecular Engineering, Johns Hopkins University
Verified email at - Homepage
Cited by
Cited by
The physics of cancer: the role of physical interactions and mechanical forces in metastasis
D Wirtz, K Konstantopoulos, PC Searson
Nature Reviews Cancer 11 (7), 512-522, 2011
Cancer cell motility: lessons from migration in confined spaces
CD Paul, P Mistriotis, K Konstantopoulos
Nature reviews cancer 17 (2), 131-140, 2017
Water permeation drives tumor cell migration in confined microenvironments
KM Stroka, H Jiang, SH Chen, Z Tong, D Wirtz, SX Sun, ...
Cell 157 (3), 611-623, 2014
Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions
OJT McCarty, SA Mousa, PF Bray, K Konstantopoulos
Blood, The Journal of the American Society of Hematology 96 (5), 1789-1797, 2000
Physical confinement alters tumor cell adhesion and migration phenotypes
EM Balzer, Z Tong, CD Paul, WC Hung, KM Stroka, AE Boggs, SS Martin, ...
The FASEB Journal 26 (10), 4045, 2012
A 3-D computational model predicts that cell deformation affects selectin-mediated leukocyte rolling
S Jadhav, CD Eggleton, K Konstantopoulos
Biophysical journal 88 (1), 96-104, 2005
Single-molecule analysis of cadherin-mediated cell-cell adhesion
P Panorchan, MS Thompson, KJ Davis, Y Tseng, K Konstantopoulos, ...
Journal of cell science 119 (1), 66-74, 2006
Cancer cells in transit: the vascular interactions of tumor cells
K Konstantopoulos, SN Thomas
Annual review of biomedical engineering 11, 177-202, 2009
Single molecule characterization of P-selectin/ligand binding
W Hanley, O McCarty, S Jadhav, Y Tseng, D Wirtz, K Konstantopoulos
Journal of biological chemistry 278 (12), 10556-10561, 2003
Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E-and L-selectin in shear flow
SN Thomas, F Zhu, RL Schnaar, CS Alves, K Konstantopoulos
Journal of biological chemistry 283 (23), 15647-15655, 2008
Venous Levels of Shear Support Neutrophil-Platelet Adhesion and Neutrophil Aggregation in Blood via P-Selectin and β2-Integrin
K Konstantopoulos, S Neelamegham, AR Burns, E Hentzen, GS Kansas, ...
Circulation 98 (9), 873-882, 1998
Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation
SH Chen, WC Hung, P Wang, C Paul, K Konstantopoulos
Scientific reports 3 (1), 1-10, 2013
A physical sciences network characterization of non-tumorigenic and metastatic cells
Scientific reports 3 (1), 1449, 2013
Biomechanics of cell interactions in shear fields
K Konstantopoulos, S Kukreti, LV McIntire
Advanced drug delivery reviews 33 (1-2), 141-164, 1998
Shear-induced platelet aggregation in normal subjects and stroke patients
K Konstantopoulos, JC Grotta, C Sills, KK Wu, JD Heliums
Thrombosis and haemostasis 74 (11), 1329-1334, 1995
CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity
WD Hanley, MM Burdick, K Konstantopoulos, R Sackstein
Cancer research 65 (13), 5812-5817, 2005
Chemotaxis of cell populations through confined spaces at single-cell resolution
ZQ Tong, EM Balzer, MR Dallas, WC Hung, KJ Stebe, K Konstantopoulos
PloS one 7 (1), e29211, 2012
Variant isoforms of CD44 are P‐and L‐selectin ligands on colon carcinoma cells
WD Hanley, SL Napier, MM Burdick, RL Schnaar, R Sackstein, ...
The FASEB journal 20 (2), 337-339, 2006
Distinct signaling mechanisms regulate migration in unconfined versus confined spaces
WC Hung, SH Chen, CD Paul, KM Stroka, YC Lo, JT Yang, ...
Journal of cell biology 202 (5), 807-824, 2013
Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis
ZR Healy, NH Lee, X Gao, MB Goldring, P Talalay, TW Kensler, ...
Proceedings of the National Academy of Sciences 102 (39), 14010-14015, 2005
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