Robust deep learning–based protein sequence design using ProteinMPNN J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ... Science 378 (6615), 49-56, 2022 | 963 | 2022 |
De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 885 | 2023 |
Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 366 | 2022 |
Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 327 | 2022 |
Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... BioRxiv, 2022.12. 09.519842, 2022 | 211 | 2022 |
Improving de novo protein binder design with deep learning NR Bennett, B Coventry, I Goreshnik, B Huang, A Allen, D Vafeados, ... Nature Communications 14 (1), 2625, 2023 | 174 | 2023 |
De novo design of high-affinity binders of bioactive helical peptides S Vázquez Torres, PJY Leung, P Venkatesh, ID Lutz, F Hink, HH Huynh, ... Nature 626 (7998), 435-442, 2024 | 75 | 2024 |
Atomically accurate de novo design of single-domain antibodies NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ... bioRxiv, 2024 | 47 | 2024 |
Geometry and expression enhance enrichment of functional yeast‐displayed ligands via cell panning LA Stern, IA Schrack, SM Johnson, A Deshpande, NR Bennett, ... Biotechnology and bioengineering 113 (11), 2328-2341, 2016 | 46 | 2016 |
High-CO2 Requirement as a Mechanism for the Containment of Genetically Modified Cyanobacteria RL Clark, GC Gordon, NR Bennett, H Lyu, TW Root, BF Pfleger ACS synthetic biology 7 (2), 384-391, 2018 | 38 | 2018 |
De novo design of high-affinity protein binders to bioactive helical peptides SV Torres, PJY Leung, ID Lutz, P Venkatesh, JL Watson, F Hink, ... Biorxiv, 2022.12. 10.519862, 2022 | 20 | 2022 |
Robust de novo design of protein binding proteins from target structural information alone L Cao, B Coventry, I Goreshnik, B Huang, JS Park, KM Jude, I Marković, ... BioRxiv, 2021.09. 04.459002, 2021 | 15 | 2021 |
Designed endocytosis-inducing proteins degrade targets and amplify signals B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, ... Nature, 1-9, 2024 | 6 | 2024 |
Designed endocytosis-triggering proteins mediate targeted degradation B Huang, M Abedi, G Ahn, B Coventry, I Sappington, R Wang, ... BioRxiv, 2023 | 6 | 2023 |
Multiple de novo designed protein binding proteins LJ Stewart, D Baker, CAO Longxing, B Coventry, I Goreshnik, B Huang, ... US Patent App. 18/576,518, 2024 | | 2024 |
Deep Learning Tools for Protein Binder Design NR Bennett University of Washington, 2023 | | 2023 |
De novo design of high-affinity protein binders to bioactive helical peptides PJY Leung, ID Lutz, P Venkatesh, JL Watson, F Hink, H Huynh, AH Yeh, ... | | 2022 |
Robust deep learning based protein sequence design using ProteinMPNN K Bera, NP King, D Baker | | |