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Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas-and TNFR1-induced apoptosis
J Bertin, RC Armstrong, S Ottilie, DA Martin, Y Wang, S Banks, GH Wang, ...
Proceedings of the National Academy of Sciences 94 (4), 1172-1176, 1997
FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis
SM Srinivasula, M Ahmad, F Bullrich, T Fernandes-Alnemri, CM Croce, ...
Journal of Biological Chemistry 272 (30), 18542-18545, 1997
Bax-and Bak-induced cell death in the fission yeast Schizosaccharomyces pombe.
JM Jürgensmeier, S Krajewski, RC Armstrong, GM Wilson, T Oltersdorf, ...
Molecular Biology of the Cell 8 (2), 325-339, 1997
Dimerization properties of human Bad: Identification of a BH-3 domain and analysis of its binding to mutant Bcl-2 and Bcl-Xl proteins
S Ottilie, JL Diaz, W Horne, J Chang, Y Wang, G Wilson, S Chang, ...
Journal of Biological Chemistry 272 (49), 30866-30872, 1997
Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.
S Ottilie, PJ Miller, DI Johnson, CL Creasy, MA Sells, S Bagrodia, ...
The EMBO Journal 14 (23), 5908-5919, 1995
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ...
Science 359 (6372), 191-199, 2018
Characterization of Pak2p, a pleckstrin homology domain-containing, p21-activated protein kinase from fission yeast
MA Sells, JT Barratt, J Caviston, S Ottilie, E Leberer, J Chernoff
Journal of Biological Chemistry 273 (29), 18490-18498, 1998
The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis
S Ottilie, J Chernoff, G Hannig, CS Hoffman, RL Erikson
Molecular and Cellular Biology 12 (12), 5571-5580, 1992
Multiple src-related kinase genes, srk1-4, in the fresh water sponge Spongilla lacustris
S Ottilie, F Raulf, A Barnekow, G Hannig, M Schartl
A fission-yeast gene encoding a protein with features of protein-tyrosine-phosphatases.
S Ottilie, J Chernoff, G Hannig, CS Hoffman, RL Erikson
Proceedings of the National Academy of Sciences 88 (8), 3455-3459, 1991
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials
Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ...
Science 362 (6419), 2018
Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein
SL Forsburg, DA Sherman, S Ottilie, JR Yasuda, JA Hodson
Genetics 147 (3), 1025-1041, 1997
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity
GM LaMonte, J Almaliti, B Bibo-Verdugo, L Keller, BY Zou, J Yang, ...
Journal of medicinal chemistry 60 (15), 6721-6732, 2017
Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome
SC Xie, DL Gillett, NJ Spillman, C Tsu, MR Luth, S Ottilie, S Duffy, ...
Journal of medicinal chemistry 61 (22), 10053-10066, 2018
Structural and functional complementation of an inactive Bcl-2 mutant by Bax truncation
S Ottilie, JL Diaz, J Chang, G Wilson, KM Tuffo, S Weeks, M McConnell, ...
Journal of Biological Chemistry 272 (27), 16955-16961, 1997
Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
MR Luth, P Gupta, S Ottilie, EA Winzeler
ACS infectious diseases 4 (3), 301-314, 2018
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor
GM Goldgof, JD Durrant, S Ottilie, E Vigil, KE Allen, F Gunawan, ...
Scientific reports 6 (1), 1-13, 2016
Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A
AC Jones, S Ottilie, AS Eustáquio, DJ Edwards, L Gerwick, BS Moore, ...
The FEBS journal 279 (7), 1243-1251, 2012
Mutational analysis of the interacting cell death regulators CED-9 and CED-4
S Ottilie, Y Wang, S Banks, J Chang, NJ Vigna, S Weeks, RC Armstrong, ...
Cell Death & Differentiation 4 (7), 526-533, 1997
Conservation of structure and expression of the c-yes andfyn genes in lower vertebrates
G Hannig, S Ottilie, M Schartl
Oncogene 6, 361-369, 1991
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