Ted M. Lakowski
Ted M. Lakowski
Associate Professor and Director of the Pharmaceutical Analysis Laboratory, University of Manitoba
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Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl-and asymmetric dimethyl-arginine residues on histone H4
TM Lakowski, A Frankel
Biochemical Journal 421 (2), 253-261, 2009
A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism
TM Lakowski, A Frankel
Journal of biological chemistry 283 (15), 10015-10025, 2008
Deep graph embedding for prioritizing synergistic anticancer drug combinations
P Jiang, S Huang, Z Fu, Z Sun, TM Lakowski, P Hu
Computational and structural biotechnology journal 18, 427-438, 2020
Transcriptional regulation of brain-derived neurotrophic factor (BDNF) by methyl CpG binding protein 2 (MeCP2): a novel mechanism for re-myelination and/or myelin repair …
T KhorshidAhmad, C Acosta, C Cortes, TM Lakowski, S Gangadaran, ...
Molecular neurobiology 53, 1092-1107, 2016
Physiologic changes in the heart following cessation of mechanical ventilation in a porcine model of donation after circulatory death: implications for cardiac transplantation
CW White, R Lillico, J Sandha, D Hasanally, F Wang, E Ambrose, A Müller, ...
American Journal of Transplantation 16 (3), 783-793, 2016
A Protein Arginine N-Methyltransferase 1 (PRMT1) and 2 Heteromeric Interaction Increases PRMT1 Enzymatic Activity
ML Pak, TM Lakowski, D Thomas, MI Vhuiyan, K Hüsecken, A Frankel
Biochemistry 50 (38), 8226-8240, 2011
Calcium‐induced folding of a fragment of calmodulin composed of EF‐hands 2 and 3
TM Lakowski, GM Lee, M Okon, RE Reid, LP McIntosh
Protein science 16 (6), 1119-1132, 2007
Nη-Substituted Arginyl Peptide Inhibitors of Protein Arginine N-Methyltransferases
TM Lakowski, P ’t Hart, CA Ahern, NI Martin, A Frankel
ACS chemical biology 5 (11), 1053-1063, 2010
SARS‐CoV‐2 multifaceted interaction with the human host. Part II: Innate immunity response, immunopathology, and epigenetics
TH Beacon, RC Su, TM Lakowski, GP Delcuve, JR Davie
IUBMB life 72 (11), 2331-2354, 2020
PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X
MI Vhuiyan, ML Pak, MA Park, D Thomas, TM Lakowski, CE Chalfant, ...
The journal of biochemistry 162 (1), 17-25, 2017
Förster resonance energy transfer measurements of cofactor‐dependent effects on protein arginine N‐methyltransferase homodimerization
D Thomas, TM Lakowski, ML Pak, JJ Kim, A Frankel
Protein Science 19 (11), 2141-2151, 2010
Approaches to measuring the activities of protein arginine N-methyltransferases
TM Lakowski, C Zurita-Lopez, SG Clarke, A Frankel
Analytical biochemistry 397 (1), 1, 2010
HDAC inhibitors induce global changes in histone lysine and arginine methylation and alter expression of lysine demethylases
R Lillico, MG Sobral, N Stesco, TM Lakowski
Journal of proteomics 133, 125-133, 2016
Selective DOT1L, LSD1, and HDAC class I inhibitors reduce HOXA9 expression in MLL-AF9 rearranged leukemia cells, but dysregulate the expression of many histone-modifying enzymes
R Lillico, CK Lawrence, TM Lakowski
Journal of proteome research 17 (8), 2657-2667, 2018
Peptidic Partial Bisubstrates as Inhibitors of the Protein Arginine N‐Methyltransferases
P 't Hart, TM Lakowski, D Thomas, A Frankel, NI Martin
ChemBioChem 12 (9), 1427-1432, 2011
Disposition, metabolism and histone deacetylase and acetyltransferase inhibition activity of tetrahydrocurcumin and other curcuminoids
JT Novaes, R Lillico, CL Sayre, K Nagabhushanam, M Majeed, Y Chen, ...
Pharmaceutics 9 (4), 45, 2017
MS3 fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM3
TM Lakowski, A Szeitz, ML Pak, D Thomas, MI Vhuiyan, J Kotthaus, ...
Journal of proteomics 80, 43-54, 2013
Antimicrobial prophylaxis for patients undergoing cardiac surgery: intraoperative cefazolin concentrations and sternal wound infections
SA Zelenitsky, D Calic, RC Arora, HP Grocott, TM Lakowski, R Lillico, ...
Antimicrobial Agents and Chemotherapy 62 (11), 10.1128/aac. 01360-18, 2018
Absolute oral bioavailability of creatine monohydrate in rats: debunking a myth
EA Alraddadi, R Lillico, JL Vennerstrom, TM Lakowski, DW Miller
Pharmaceutics 10 (1), 31, 2018
Quantification of cefazolin in serum and adipose tissue by ultra high performance liquid chromatography-Tandem mass spectrometry (UHPLC–MS/MS): Application to a pilot study of …
R Lillico, CL Sayre, DS Sitar, NM Davies, CM Baron, TM Lakowski
Journal of Chromatography B 1031, 94-98, 2016
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