| Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity S Boudina, S Sena, BT O’Neill, P Tathireddy, ME Young, ED Abel Circulation 112 (17), 2686-2695, 2005 | 609 | 2005 |
| Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts PK Mazumder, BT O’Neill, MW Roberts, J Buchanan, UJ Yun, ... Diabetes 53 (9), 2366-2374, 2004 | 544 | 2004 |
| Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart S Boudina, H Bugger, S Sena, BT O'Neill, VG Zaha, O Ilkun, JJ Wright, ... Circulation 119 (9), 1272-1283, 2009 | 329 | 2009 |
| Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling S Softic, MK Gupta, GX Wang, S Fujisaka, BT O’Neill, TN Rao, ... The Journal of clinical investigation 127 (11), 4059-4074, 2017 | 303 | 2017 |
| Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation E Jing, BT O’Neill, MJ Rardin, A Kleinridders, OR Ilkeyeva, S Ussar, ... Diabetes 62 (10), 3404-3417, 2013 | 270 | 2013 |
| Akt1 in the cardiovascular system: friend or foe? BT O Neill, ED Abel Journal of Clinical Investigation 115 (8), 2059, 2005 | 171 | 2005 |
| A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy BT O'Neill, J Kim, AR Wende, HA Theobald, J Tuinei, J Buchanan, A Guo, ... Cell metabolism 6 (4), 294-306, 2007 | 162 | 2007 |
| Differential role of insulin/IGF-1 receptor signaling in muscle growth and glucose homeostasis BT O’Neill, HPMM Lauritzen, MF Hirshman, G Smyth, LJ Goodyear, ... Cell reports 11 (8), 1220-1235, 2015 | 153 | 2015 |
| FoxO transcription factors are critical regulators of diabetes-related muscle atrophy BT O’Neill, G Bhardwaj, CM Penniman, MT Krumpoch, PA Suarez Beltran, ... Diabetes 68 (3), 556-570, 2019 | 151 | 2019 |
| Diet‐induced obesity causes insulin resistance in mouse brown adipose tissue C Roberts‐Toler, BT O'Neill, AM Cypess Obesity 23 (9), 1765-1770, 2015 | 150 | 2015 |
| Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis BT O’Neill, KY Lee, K Klaus, S Softic, MT Krumpoch, J Fentz, KI Stanford, ... The Journal of clinical investigation 126 (9), 3433-3446, 2016 | 146 | 2016 |
| Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression W Cai, M Sakaguchi, A Kleinridders, G Gonzalez-Del Pino, JM Dreyfuss, ... Nature communications 8 (1), 14892, 2017 | 145 | 2017 |
| Differential roles of insulin and IGF-1 receptors in adipose tissue development and function J Boucher, S Softic, A El Ouaamari, MT Krumpoch, A Kleinridders, ... Diabetes 65 (8), 2201-2213, 2016 | 136 | 2016 |
| Adipocyte dynamics and reversible metabolic syndrome in mice with an inducible adipocyte-specific deletion of the insulin receptor M Sakaguchi, S Fujisaka, W Cai, JN Winnay, M Konishi, BT O'Neill, M Li, ... Cell metabolism 25 (2), 448-462, 2017 | 124 | 2017 |
| Insulin regulation of proteostasis and clinical implications HA James, BT O'Neill, KS Nair Cell metabolism 26 (2), 310-323, 2017 | 112 | 2017 |
| Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of … AR Wende, BT O'Neill, H Bugger, C Riehle, J Tuinei, J Buchanan, ... Molecular and cellular biology 35 (5), 831-846, 2015 | 100 | 2015 |
| Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation Y Zhu, RO Pereira, BT O'Neill, C Riehle, O Ilkun, AR Wende, TA Rawlings, ... Molecular endocrinology 27 (1), 172-184, 2013 | 87 | 2013 |
| Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity S Boudina, S Sena, C Sloan, A Tebbi, YH Han, BT O'Neill, RC Cooksey, ... Endocrinology 153 (6), 2677-2688, 2012 | 71 | 2012 |
| Multi-dimensional transcriptional remodeling by physiological insulin in vivo TM Batista, R Garcia-Martin, W Cai, M Konishi, BT O’Neill, M Sakaguchi, ... Cell reports 26 (12), 3429-3443. e3, 2019 | 67 | 2019 |
| Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses AR Wende, J Kim, WL Holland, BE Wayment, BT O’Neill, J Tuinei, ... American Journal of Physiology-Heart and Circulatory Physiology 313 (6 …, 2017 | 51 | 2017 |
Adam R. Wende, PhD, FAHAAssociate Professor of Pathology, University of Alabama at BirminghamVerified email at uab.edu
