| Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation R Amato, L D’Antona, G Porciatti, V Agosti, M Menniti, C Rinaldo, N Costa, ... Journal of molecular medicine 87, 1221-1239, 2009 | 115 | 2009 |
| Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas C Abbruzzese, S Mattarocci, L Pizzuti, AM Mileo, P Visca, B Antoniani, ... Journal of experimental & clinical cancer research 31, 1-7, 2012 | 104 | 2012 |
| Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy C Talarico, L D'Antona, D Scumaci, A Barone, F Gigliotti, CV Fiumara, ... Oncotarget 6 (35), 37511, 2015 | 86 | 2015 |
| SGK1, the new player in the game of resistance: chemo-radio molecular target and strategy for inhibition C Talarico, V Dattilo, L D'antona, M Menniti, C Bianco, F Ortuso, S Alcaro, ... Cellular physiology and biochemistry 39 (5), 1863-1876, 2016 | 76 | 2016 |
| SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells C Talarico, V Dattilo, L D'Antona, A Barone, N Amodio, S Belviso, ... Oncotarget 7 (13), 15868, 2016 | 69 | 2016 |
| Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells R Amato, D Scumaci, L D'antona, R Iuliano, M Menniti, M Di Sanzo, ... Oncogene 32 (38), 4572-4578, 2013 | 63 | 2013 |
| IL-2 signals through Sgk1 and inhibits proliferation and apoptosis in kidney cancer cells R Amato, M Menniti, V Agosti, R Boito, N Costa, HM Bond, V Barbieri, ... Journal of molecular medicine 85, 707-721, 2007 | 62 | 2007 |
| SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation L D''antona, R Amato, C Talarico, F Ortuso, M Menniti, V Dattilo, R Iuliano, ... Cellular physiology and biochemistry 35 (5), 2006-2018, 2015 | 61 | 2015 |
| The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells D Conza, P Mirra, G Cali, T Tortora, L Insabato, F Fiory, S Schenone, ... Journal of cellular physiology 232 (12), 3735-3743, 2017 | 59 | 2017 |
| Relative resistance of SGK1 knockout mice against chemical carcinogenesis O Nasir, K Wang, M Föller, S Gu, M Bhandaru, TF Ackermann, KM Boini, ... IUBMB life 61 (7), 768-776, 2009 | 57 | 2009 |
| Safety and efficacy of non‐steroidal anti‐inflammatory drugs to reduce ileus after colorectal surgery EuroSurg Collaborative, SJ Chapman, D Clerc, R Blanco‐Colino, A Otto, ... British Journal of Surgery 107 (2), e161-e169, 2020 | 55 | 2020 |
| In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold F Ortuso, R Amato, A Artese, L D’antona, G Costa, C Talarico, F Gigliotti, ... Journal of chemical information and modeling 54 (7), 1828-1832, 2014 | 44 | 2014 |
| Indole and 2, 4-Thiazolidinedione conjugates as potential anticancer modulators DM Corigliano, R Syed, S Messineo, A Lupia, R Patel, CVR Reddy, ... PeerJ 6, e5386, 2018 | 43 | 2018 |
| The emerging role of SGK1 (serum-and glucocorticoid-regulated kinase 1) in major depressive disorder: hypothesis and mechanisms V Dattilo, R Amato, N Perrotti, M Gennarelli Frontiers in Genetics 11, 826, 2020 | 39 | 2020 |
| The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the 64CuCl2 in Human Glioblastoma Multiforme Cells G Catalogna, C Talarico, V Dattilo, V Gangemi, F Calabria, L D’Antona, ... Cellular Physiology and Biochemistry 43 (1), 108-119, 2017 | 39 | 2017 |
| 60kDa lysophospholipase, a new Sgk1 molecular partner involved in the regulation of ENaC M Menniti, R Iuliano, M Föller, M Sopjani, I Alesutan, S Mariggiò, ... Cellular physiology and biochemistry 26 (4-5), 587-596, 2010 | 39 | 2010 |
| SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation V Dattilo, L D’Antona, C Talarico, M Capula, G Catalogna, R Iuliano, ... Scientific reports 7 (1), 45361, 2017 | 32 | 2017 |
| The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells S Matteoni, C Abbruzzese, P Matarrese, G De Luca, AM Mileo, S Miccadei, ... Journal of Experimental & Clinical Cancer Research 38, 1-13, 2019 | 30 | 2019 |
| Deregulation of SGK1 in ulcerative colitis: a paradoxical relationship between immune cells and colonic epithelial cells R Spagnuolo, V Dattilo, L D’Antona, C Cosco, R Tallerico, V Ventura, ... Inflammatory bowel diseases 24 (9), 1967-1977, 2018 | 30 | 2018 |
| Serum and glucocorticoid-regulated kinase Sgk1 inhibits insulin-dependent activation of phosphomannomutase 2 in transfected COS-7 cells M Menniti, R Iuliano, R Amato, R Boito, M Corea, I Le Pera, E Gulletta, ... American Journal of Physiology-Cell Physiology 288 (1), C148-C155, 2005 | 30 | 2005 |
