| A comparison of methods to assess cell mechanical properties PH Wu, DRB Aroush, A Asnacios, WC Chen, ME Dokukin, BL Doss, ... Nature methods 15, 491-498, 2018 | 401 | 2018 |
| Transient opening of the mitochondrial permeability transition pore induces microdomain calcium transients in astrocyte processes A Agarwal, PH Wu, EG Hughes, M Fukaya, MA Tischfield, AJ Langseth, ... Neuron 93 (3), 587-605. e7, 2017 | 345 | 2017 |
| Three-dimensional cell migration does not follow a random walk PH Wu, A Giri, SX Sun, D Wirtz Proceedings of the National Academy of Sciences 111 (11), 3949-3954, 2014 | 319 | 2014 |
| Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions SI Fraley, P Wu, L He, Y Feng, R Krisnamurthy, GD Longmore, D Wirtz Scientific reports 5 (1), 1-13, 2015 | 219 | 2015 |
| The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration SB Khatau, RJ Bloom, S Bajpai, D Razafsky, S Zang, A Giri, PH Wu, ... Scientific reports 2 (1), 1-11, 2012 | 179 | 2012 |
| A physical sciences network characterization of non-tumorigenic and metastatic cells Scientific reports 3 (1), 1449, 2013 | 169 | 2013 |
| High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity Y Lu, JJ Chen, L Mu, Q Xue, Y Wu, PH Wu, J Li, AO Vortmeyer, ... Analytical chemistry 85 (4), 2548-2556, 2013 | 158 | 2013 |
| Confinement sensing and signal optimization via Piezo1/PKA and myosin II pathways WC Hung, JR Yang, CL Yankaskas, BS Wong, PH Wu, C Pardo-Pastor, ... Cell reports 15 (7), 1430-1441, 2016 | 142 | 2016 |
| Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration H Jayatilaka, P Tyle, JJ Chen, M Kwak, J Ju, HJ Kim, JSH Lee, PH Wu, ... Nature communications 8 (1), 15584, 2017 | 133 | 2017 |
| Evolution of cellular morpho-phenotypes in cancer metastasis PH Wu, JM Phillip, SB Khatau, WC Chen, J Stirman, S Rosseel, K Tschudi, ... Scientific reports 5 (1), 18437, 2015 | 124 | 2015 |
| Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model PH Wu, A Giri, D Wirtz Nature protocols 10 (3), 517-527, 2015 | 105 | 2015 |
| Hypoxia Selectively Enhances Integrin α5β1 Receptor Expression in Breast Cancer to Promote MetastasisHypoxia Enhances Integrin α5β1 to Promote Metastasis JA Ju, I Godet, IC Ye, J Byun, H Jayatilaka, SJ Lee, L Xiang, D Samanta, ... Molecular Cancer Research 15 (6), 723-734, 2017 | 102 | 2017 |
| Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer MH Lee, PH Wu, JR Staunton, R Ros, GD Longmore, D Wirtz Biophysical journal 102 (12), 2731-2741, 2012 | 99 | 2012 |
| Single-cell morphology encodes metastatic potential PH Wu, DM Gilkes, JM Phillip, A Narkar, TWT Cheng, J Marchand, ... Science advances 6 (4), eaaw6938, 2020 | 91 | 2020 |
| High-throughput ballistic injection nanorheology to measure cell mechanics PH Wu, CM Hale, WC Chen, JSH Lee, Y Tseng, D Wirtz Nature Protocols 7 (1), 155-170, 2012 | 72 | 2012 |
| Collective cancer cell invasion induced by coordinated contractile stresses AMJ Valencia, PH Wu, ON Yogurtcu, P Rao, J DiGiacomo, I Godet, L He, ... Oncotarget 6 (41), 43438, 2015 | 70 | 2015 |
| Biophysical and biomolecular determination of cellular age in humans JM Phillip, PH Wu, DM Gilkes, W Williams, S McGovern, J Daya, J Chen, ... Nature biomedical engineering 1 (7), 0093, 2017 | 68 | 2017 |
| Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication D Ardeljan, JP Steranka, C Liu, Z Li, MS Taylor, LM Payer, M Gorbounov, ... Nature structural & molecular biology 27 (2), 168-178, 2020 | 64 | 2020 |
| Differential vesicular sorting of AMPA and GABAA receptors Y Gu, SL Chiu, B Liu, PH Wu, M Delannoy, DT Lin, D Wirtz, RL Huganir Proceedings of the National Academy of Sciences 113 (7), E922-E931, 2016 | 62 | 2016 |
| Multi-nucleated cells use ROS to induce breast cancer chemo-resistance in vitro and in vivo A Parekh, S Das, S Parida, CK Das, D Dutta, SK Mallick, PH Wu, ... Oncogene 37 (33), 4546-4561, 2018 | 55 | 2018 |
Denis WirtzT.H. Smoot Professor of Engineering Science, Pathology, and Oncology; VP Research, Johns HopkinsVerified email at jhu.edu
