PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing Q Zhao, G Rank, YT Tan, H Li, RL Moritz, RJ Simpson, L Cerruti, DJ Curtis, ... Nature structural & molecular biology 16 (3), 304-311, 2009 | 653 | 2009 |
The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal MP McCormack, LF Young, S Vasudevan, CA de Graaf, R Codrington, ... Science 327 (5967), 879-883, 2010 | 279 | 2010 |
The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12 MA Hall, DJ Curtis, D Metcalf, AG Elefanty, K Sourris, L Robb, JR Göthert, ... Proceedings of the National Academy of Sciences 100 (3), 992-997, 2003 | 277 | 2003 |
Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival GP Souroullas, JM Salmon, F Sablitzky, DJ Curtis, MA Goodell Cell stem cell 4 (2), 180-186, 2009 | 158 | 2009 |
LIM-domain-only proteins in cancer JM Matthews, K Lester, S Joseph, DJ Curtis Nature Reviews Cancer 13 (2), 111-122, 2013 | 149 | 2013 |
Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation MJ Nemeth, DJ Curtis, MR Kirby, LJ Garrett-Beal, NE Seidel, AP Cline, ... Blood 102 (4), 1298-1306, 2003 | 122 | 2003 |
SCL is required for normal function of short-term repopulating hematopoietic stem cells DJ Curtis, MA Hall, LJ Van Stekelenburg, L Robb, SM Jane, CG Begley Blood 103 (9), 3342-3348, 2004 | 109 | 2004 |
Granulocyte colony-stimulating factor and stem cell factor improve endogenous repair after myocardial infarction P Kanellakis, NJ Slater, XJ Du, A Bobik, DJ Curtis Cardiovascular research 70 (1), 117-125, 2006 | 101 | 2006 |
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling S Goossens, E Radaelli, O Blanchet, K Durinck, J Van der Meulen, ... Nature communications 6 (1), 5794, 2015 | 97 | 2015 |
Chronic airflow obstruction in long-term survivors of allogeneic bone marrow transplantation. DJ Curtis, A Smale, F Thien, AP Schwarer, J Szer Bone marrow transplantation 16 (1), 169-173, 1995 | 90 | 1995 |
Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL MP McCormack, BJ Shields, JT Jackson, C Nasa, W Shi, NJ Slater, ... Blood, The Journal of the American Society of Hematology 122 (12), 2093-2103, 2013 | 79 | 2013 |
Underestimation of myelodysplastic syndrome incidence by cancer registries: results from a population‐based data linkage study ZK McQuilten, EM Wood, MN Polizzotto, LJ Campbell, M Wall, DJ Curtis, ... Cancer 120 (11), 1686-1694, 2014 | 70 | 2014 |
Recombinant soluble interleukin-11 (IL-11) receptor α-chain can act as an IL-11 antagonist DJ Curtis, DJ Hilton, B Roberts, L Murray, N Nicola, CG Begley Blood, The Journal of the American Society of Hematology 90 (11), 4403-4412, 1997 | 68 | 1997 |
Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant G Rank, R Sutton, V Marshall, RJ Lundie, J Caddy, T Romeo, ... Blood, The Journal of the American Society of Hematology 113 (14), 3352-3362, 2009 | 64 | 2009 |
The generation and properties of human macrophage populations from hemopoietic stem cells KJ Way, H Dinh, MR Keene, KE White, FIL Clanchy, P Lusby, J Roiniotis, ... Journal of Leucocyte Biology 85 (5), 766-778, 2009 | 61 | 2009 |
Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene MA Hall, NJ Slater, CG Begley, JM Salmon, LJ Van Stekelenburg, ... Molecular and cellular biology, 2005 | 61 | 2005 |
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis MP McCormack, MA Hall, SM Schoenwaelder, Q Zhao, S Ellis, ... Blood 108 (7), 2248-2256, 2006 | 59 | 2006 |
The molecular basis of Lmo2-induced T-cell acute lymphoblastic leukemia DJ Curtis, MP McCormack Clinical Cancer Research 16 (23), 5618-5623, 2010 | 54 | 2010 |
Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome CI Slape, J Saw, JBM Jowett, PD Aplan, A Strasser, SM Jane, DJ Curtis Blood, The Journal of the American Society of Hematology 120 (12), 2475-2483, 2012 | 50 | 2012 |
The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms SL Siggins, NYN Nguyen, MP McCormack, S Vasudevan, R Villani, ... Blood, The Journal of the American Society of Hematology 114 (5), 995-1004, 2009 | 49 | 2009 |