Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-κB P Suboj, S Babykutty, DRV Gopi, RS Nair, P Srinivas, S Gopala European journal of pharmaceutical sciences 45 (5), 581-591, 2012 | 160 | 2012 |
The molecular response of vanadium complexes of nicotinoyl hydrazone in cervical cancers—a possible interference with HPV oncogenic markers RS Nair, M Kuriakose, V Somasundaram, V Shenoi, MRP Kurup, ... Life sciences 116 (2), 90-97, 2014 | 51 | 2014 |
Plumbagin, a naphthaquinone derivative induces apoptosis in BRCA 1/2 defective castrate resistant prostate cancer cells as well as prostate cancer stem-like cells RS Reshma, KH Sreelatha, V Somasundaram, R Nadhan, RS Nair, ... Pharmacological research 105, 134-145, 2016 | 30 | 2016 |
BRCA1 regulation on β-hCG: a mechanism for tumorigenicity in BRCA1 defective breast cancer SK Sengodan, R Nadhan, RS Nair, SK Hemalatha, V Somasundaram, ... Oncogenesis 6 (9), e376-e376, 2017 | 28 | 2017 |
Structure activity relationship of plumbagin in BRCA1 related cancer cells T KA, S KC, RS Nair, A Banerji, V Somasundaram, P Srinivas Molecular carcinogenesis 52 (5), 392-403, 2013 | 27 | 2013 |
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3 SK Singh, S Kumar, N Viswakarma, DR Principe, S Das, G Sondarva, ... Oncogene 40 (43), 6153-6165, 2021 | 22 | 2021 |
Human epidermal growth factor receptor 2 (HER2) impedes MLK3 kinase activity to support breast cancer cell survival S Das, G Sondarva, N Viswakarma, RS Nair, C Osipo, G Tzivion, B Rana, ... Journal of Biological Chemistry 290 (35), 21705-21712, 2015 | 20 | 2015 |
Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer DR Principe, AF Aissa, S Kumar, TND Pham, PW Underwood, R Nair, ... Proceedings of the National Academy of Sciences 119 (18), e2200143119, 2022 | 18 | 2022 |
Molecular trail for the anticancer behavior of a novel copper carbohydrazone complex in BRCA1 mutated breast cancer RS Nair, ME Potti, R Thankappan, SK Chandrika, MRP Kurup, P Srinivas Molecular carcinogenesis 56 (5), 1501-1514, 2017 | 18 | 2017 |
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity S Kumar, SK Singh, N Viswakarma, G Sondarva, RS Nair, P Sethupathi, ... Proceedings of the National Academy of Sciences 117 (14), 7961-7970, 2020 | 17 | 2020 |
Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1 S Das, RS Nair, R Mishra, G Sondarva, N Viswakarma, H Abdelkarim, ... Oncogene 38 (19), 3569-3584, 2019 | 17* | 2019 |
Berberine represses β-catenin translation involving 4E-BPs in hepatocellular carcinoma cells K Vishnoi, R Ke, KS Saini, N Viswakarma, RS Nair, S Das, Z Chen, ... Molecular Pharmacology 99 (1), 1-16, 2021 | 16 | 2021 |
Increased sensitivity of BRCA defective triple negative breast tumors to plumbagin through induction of DNA Double Strand Breaks (DSB) RS Nair, JM Kumar, J Jose, V Somasundaram, SK Hemalatha, ... Scientific Reports 6 (1), 26631, 2016 | 15 | 2016 |
Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development N Viswakarma, G Sondarva, DR Principe, RS Nair, S Kumar, SK Singh, ... Cancer letters 515, 1-13, 2021 | 13 | 2021 |
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8+ T cells S Kumar, SK Singh, N Viswakarma, G Sondarva, RS Nair, P Sethupathi, ... Journal for Immunotherapy of Cancer 8 (2), 2020 | 11 | 2020 |
β-hCG-induced mutant BRCA1 ignites drug resistance in susceptible breast tissue SK Sengodan, SK Hemalatha, R Nadhan, T Somanathan, AP Mathew, ... Carcinogenesis 40 (11), 1415-1426, 2019 | 6 | 2019 |
Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ER-positive breast cancer pathogenesis N Viswakarma, RS Nair, G Sondarva, S Das, L Ibrahimi, Z Chen, S Sinha, ... Oncotarget 8 (20), 33172, 2017 | 4 | 2017 |
Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles S Kumar, S Das, J Sun, Y Huang, SK Singh, P Srivastava, G Sondarva, ... Proceedings of the National Academy of Sciences 119 (38), e2205454119, 2022 | 3 | 2022 |
TrkA expression directs the anti-neoplastic activity of MLK3 inhibitors in triple-negative breast cancer RS Nair, S Kumar, S Das, SK Singh, P Srivastava, G Sondarva, A Rao, ... Oncogene 42 (14), 1132-1143, 2023 | 2 | 2023 |
Paradoxical Role of MLK3-CTLA-4 axis in Triple-negative Breast Cancer and CD8+ T cells S Kumar, SK Singh, N Viswakarma, G Sondarva, RS Nair, G Thatcher, ... The Journal of Immunology 204 (1_Supplement), 241.7-241.7, 2020 | 1 | 2020 |