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Helena Safavi
Helena Safavi
Associate Professor
Verified email at sund.ku.dk - Homepage
Title
Cited by
Cited by
Year
The Opisthorchis viverrini genome provides insights into life in the bile duct
ND Young, N Nagarajan, SJ Lin, PK Korhonen, AR Jex, RS Hall, ...
Nature communications 5 (1), 4378, 2014
1732014
Specialized insulin is used for chemical warfare by fish-hunting cone snails
H Safavi-Hemami, J Gajewiak, S Karanth, SD Robinson, B Ueberheide, ...
Proceedings of the National Academy of Sciences 112 (6), 1743-1748, 2015
1702015
Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae
SD Robinson, H Safavi-Hemami, LD McIntosh, AW Purcell, RS Norton, ...
PloS one 9 (2), e87648, 2014
1372014
Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways
H Safavi-Hemami, SE Brogan, BM Olivera
Journal of proteomics 190, 12-20, 2019
1232019
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin
JG Menting, J Gajewiak, CA MacRaild, DHC Chou, MM Disotuar, ...
Nature structural & molecular biology 23 (10), 916-920, 2016
872016
Hormone-like peptides in the venoms of marine cone snails
SD Robinson, Q Li, PK Bandyopadhyay, J Gajewiak, M Yandell, ...
General and comparative endocrinology 244, 11-18, 2017
712017
Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization
H Safavi-Hemami, H Hu, DG Gorasia, PK Bandyopadhyay, PD Veith, ...
Molecular & cellular proteomics 13 (4), 938-953, 2014
662014
Insights into the origins of fish hunting in venomous cone snails from studies of Conus tessulatus
JW Aman, JS Imperial, B Ueberheide, MM Zhang, M Aguilar, D Taylor, ...
Proceedings of the National Academy of Sciences 112 (16), 5087-5092, 2015
652015
Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor
P Ahorukomeye, MM Disotuar, J Gajewiak, S Karanth, M Watkins, ...
Elife 8, e41574, 2019
572019
Venom insulins of cone snails diversify rapidly and track prey taxa
H Safavi-Hemami, A Lu, Q Li, AE Fedosov, J Biggs, P Showers Corneli, ...
Molecular biology and evolution 33 (11), 2924-2934, 2016
542016
Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway
H Safavi-Hemami, WA Siero, DG Gorasia, ND Young, D MacMillan, ...
Journal of proteome research 10 (9), 3904-3919, 2011
492011
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles
X Xiong, JG Menting, MM Disotuar, NA Smith, CA Delaine, G Ghabash, ...
Nature structural & molecular biology 27 (7), 615-624, 2020
47*2020
Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides
H Safavi-Hemami, Q Li, RL Jackson, AS Song, W Boomsma, ...
Proceedings of the National Academy of Sciences 113 (12), 3227-3232, 2016
462016
Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins
H Safavi-Hemami, G Bulaj, BM Olivera, NA Williamson, AW Purcell
Journal of biological chemistry 285 (17), 12735-12746, 2010
442010
Proteomic interrogation of venom delivery in marine cone snails: novel insights into the role of the venom bulb
H Safavi-Hemami, ND Young, NA Williamson, AW Purcell
Journal of proteome research 9 (11), 5610-5619, 2010
432010
Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails
H Safavi-Hemami, DG Gorasia, AM Steiner, NA Williamson, JA Karas, ...
Journal of Biological Chemistry 287 (41), 34288-34303, 2012
422012
A prominent role of PDIA6 in processing of misfolded proinsulin
DG Gorasia, NL Dudek, H Safavi-Hemami, RA Perez, RB Schittenhelm, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864 (6), 715-723, 2016
392016
Pancreatic beta cells are highly susceptible to oxidative and ER stresses during the development of diabetes
DG Gorasia, NL Dudek, PD Veith, R Shankar, H Safavi-Hemami, ...
Journal of Proteome Research 14 (2), 688-699, 2015
382015
Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom
SD Robinson, H Safavi-Hemami, S Raghuraman, JS Imperial, ...
Journal of proteomics 114, 38-47, 2015
382015
Divergence of the Venom Exogene Repertoire in Two Sister Species of Turriconus
Q Li, N Barghi, A Lu, AE Fedosov, PK Bandyopadhyay, AO Lluisma, ...
Genome biology and evolution 9 (9), 2211-2225, 2017
372017
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