Synthesis, anticancer activity and molecular modeling studies of 1, 2, 4-triazole derivatives as EGFR inhibitors HAM El-Sherief, BGM Youssif, SNA Bukhari, AH Abdelazeem, ... European journal of medicinal chemistry 156, 774-789, 2018 | 160 | 2018 |
A comprehensive overview of globally approved JAK inhibitors AM Shawky, FA Almalki, AN Abdalla, AH Abdelazeem, AM Gouda Pharmaceutics 14 (5), 1001, 2022 | 94 | 2022 |
Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents AH Abdelazeem, SA Abdelatef, MT El-Saadi, HA Omar, SI Khan, ... European Journal of Pharmaceutical Sciences 62, 197-211, 2014 | 80 | 2014 |
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino [1, 2-a] indol-1 (2H)-ones as potential anticancer … BGM Youssif, MH Abdelrahman, AH Abdelazeem, HM Ibrahim, OIA Salem, ... European Journal of Medicinal Chemistry 146, 260-273, 2018 | 66 | 2018 |
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance GF Zha, HL Qin, BGM Youssif, MW Amjad, MAG Raja, AH Abdelazeem, ... European Journal of Medicinal Chemistry 135, 34-48, 2017 | 64 | 2017 |
Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity FAM Mohamed, HAM Gomaa, OM Hendawy, AT Ali, HS Farghaly, ... Bioorganic Chemistry 112, 104960, 2021 | 50 | 2021 |
Wasp venom biochemical components and their potential in biological applications and nanotechnological interventions A Abd El-Wahed, N Yosri, HH Sakr, M Du, AFM Algethami, C Zhao, ... Toxins 13 (3), 206, 2021 | 50 | 2021 |
Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory … MH Abdelrahman, BGM Youssif, AH Abdelazeem, HM Ibrahim, ... European Journal of Medicinal Chemistry 127, 972-985, 2017 | 49 | 2017 |
Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents AH Abdelazeem, AM Gouda, HA Omar, MF Tolba Bioorganic Chemistry 57, 132-141, 2014 | 49 | 2014 |
Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile AH Abdelazeem, MT El-Saadi, AGS El-Din, HA Omar, SM El-Moghazy Bioorganic & medicinal chemistry 25 (2), 665-676, 2017 | 45 | 2017 |
Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities AH Abdelazeem, MT El-Saadi, EG Said, BGM Youssif, HA Omar, ... Bioorganic Chemistry 75, 127-138, 2017 | 44 | 2017 |
Design, synthesis and pharmacological evaluation of novel pyrrolizine derivatives as potential anticancer agents AM Gouda, AH Abdelazeem, ESA Arafa, KRA Abdellatif Bioorganic chemistry 53, 1-7, 2014 | 44 | 2014 |
Design, synthesis and anticancer evaluation of novel spirobenzo [h] chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities SA Abdelatef, MT El-Saadi, NH Amin, AH Abdelazeem, HA Omar, ... European journal of medicinal chemistry 150, 567-578, 2018 | 42 | 2018 |
OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro EA Arafa, AH Abdelazeem, HH Arab, HA Omar Acta Pharmacologica Sinica 35 (3), 394-400, 2014 | 36 | 2014 |
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents AH Abdelazeem, SI Khan, SW White, KJ Sufka, CR McCurdy Bioorganic & medicinal chemistry 23 (13), 3248-3259, 2015 | 35 | 2015 |
Synthesis and pharmacological characterization of a novel sigma receptor ligand with improved metabolic stability and antagonistic effects against methamphetamine MJ Seminerio, MJ Robson, AH Abdelazeem, C Mesangeau, ... The AAPS journal 14, 43-51, 2012 | 35 | 2012 |
An integrated overview on pyrrolizines as potential anti-inflammatory, analgesic and antipyretic agents AM Gouda, AH Abdelazeem European Journal of Medicinal Chemistry 114, 257-292, 2016 | 33 | 2016 |
Design, synthesis, and biological evaluation of some novel pyrrolizine derivatives as COX inhibitors with anti-inflammatory/analgesic activities and low ulcerogenic liability AM Gouda, HI Ali, WH Almalki, MA Azim, MAS Abourehab, ... Molecules 21 (2), 201, 2016 | 31 | 2016 |
Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists CRMC Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice ... Journal of Pharmacology and Experimental Therapeutics, 2016 | 30 | 2016 |
Synthesis, biological evaluation and kinase profiling of novel S-benzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazole derivatives as cytotoxic agents with apoptosis-inducing activity AH Abdelazeem, AM Alqahtani, HA Omar, SNA Bukhari, AM Gouda Journal of Molecular Structure 1219, 128567, 2020 | 29 | 2020 |