Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression D Gardner-Stephen, JM Heydel, A Goyal, Y Lu, W Xie, T Lindblom, ... Drug Metabolism and Disposition 32 (3), 340-347, 2004 | 205 | 2004 |
A self-inducible heterologous protein expression system in Escherichia coli L Briand, G Marcion, A Kriznik, JM Heydel, Y Artur, C Garrido, ... Scientific reports 6 (1), 33037, 2016 | 157 | 2016 |
Odorant‐binding proteins and xenobiotic metabolizing enzymes: implications in olfactory perireceptor events JM Heydel, A Coelho, N Thiebaud, A Legendre, AML Bon, P Faure, ... The Anatomical Record 296 (9), 1333-1345, 2013 | 155 | 2013 |
Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier A Minn, S Leclerc, JM Heydel, AL Minn, C Denizot, M Cattarelli, P Netter, ... Journal of drug targeting 10 (4), 285-296, 2002 | 153 | 2002 |
Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns P Debersac, JM Heydel, MJ Amiot, H Goudonnet, Y Artur, M Suschetet, ... Food and Chemical Toxicology 39 (9), 907-918, 2001 | 138 | 2001 |
Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes A Lançon, N Hanet, B Jannin, D Delmas, JM Heydel, G Lizard, ... Drug metabolism and disposition 35 (5), 699-703, 2007 | 135 | 2007 |
Odorant metabolism catalyzed by olfactory mucosal enzymes influences peripheral olfactory responses in rats N Thiebaud, S Veloso Da Silva, I Jakob, G Sicard, J Chevalier, ... PloS one 8 (3), e59547, 2013 | 86 | 2013 |
Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element Y Lu, JM Heydel, X Li, S Bratton, T Lindblom, A Radominska-Pandya Drug metabolism and disposition 33 (7), 937-946, 2005 | 71 | 2005 |
Glucuronidation of odorant molecules in the rat olfactory system. Activity, expression and age-linked modifications of UDP-glucuronosyltransferase isoforms, UGT1A6 and UGT2A1 … S Leclerc, JM Heydel, V Amossé, D Gradinaru, M Cattarelli, Y Artur, ... Molecular brain research 107 (2), 201-213, 2002 | 63 | 2002 |
UDP-glucuronosyltransferases (UGTs) in neuro-olfactory tissues: expression, regulation, and function JM Heydel, EJ Holsztynska, A Legendre, N Thiebaud, Y Artur, AML Bon Drug metabolism reviews 42 (1), 74-97, 2010 | 61 | 2010 |
Cytochrome P450-dependent metabolism of caffeine in Drosophila melanogaster A Coelho, S Fraichard, G Le Goff, P Faure, Y Artur, JF Ferveur, JM Heydel PLoS One 10 (2), e0117328, 2015 | 55 | 2015 |
Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis JM Heydel, S Leclerc, P Bernard, H Pelczar, D Gradinaru, J Magdalou, ... Molecular brain research 90 (1), 83-92, 2001 | 55 | 2001 |
Characterization of a Drosophila glutathione transferase involved in isothiocyanate detoxification D Gonzalez, S Fraichard, P Grassein, P Delarue, P Senet, A Nicolaï, ... Insect biochemistry and molecular biology 95, 33-43, 2018 | 52 | 2018 |
Effects of endocrine disruptors on genes associated with 17β-estradiol metabolism and excretion N Hanet, A Lancon, D Delmas, B Jannin, MC Chagnon, ... Steroids 73 (12), 1242-1251, 2008 | 46 | 2008 |
Validation of a set of reference genes to study response to herbicide stress in grasses C Petit, F Pernin, JM Heydel, C Délye BMC research notes 5, 1-10, 2012 | 44 | 2012 |
Expression and differential localization of xenobiotic transporters in the rat olfactory neuro-epithelium N Thiebaud, F Menetrier, C Belloir, AL Minn, F Neiers, Y Artur, AM Le Bon, ... Neuroscience letters 505 (2), 180-185, 2011 | 40 | 2011 |
Effect of oxidative stress on UDP-glucuronosyltransferases in rat astrocytes D Gradinaru, AL Minn, Y Artur, A Minn, JM Heydel Toxicology letters 213 (3), 316-324, 2012 | 38 | 2012 |
Nasal odorant metabolism: enzymes, activity and function in olfaction JM Heydel, P Faure, F Neiers Drug Metabolism Reviews 51 (2), 224-245, 2019 | 35 | 2019 |
Characterization of microsomal cytochrome P450-dependent monooxygenases in the rat olfactory mucosa AL Minn, H Pelczar, C Denizot, M Martinet, JM Heydel, B Walther, A Minn, ... Drug metabolism and disposition 33 (8), 1229-1237, 2005 | 34 | 2005 |
Ex vivo real-time monitoring of volatile metabolites resulting from nasal odorant metabolism A Robert-Hazotte, R Schoumacker, E Semon, L Briand, E Guichard, ... Scientific reports 9 (1), 2492, 2019 | 33 | 2019 |