Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia JA Powell, AC Lewis, W Zhu, J Toubia, MR Pitman, ... Blood 129 (6), 771-782, 2017 | 80 | 2017 |
Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases KT Lawlor, LV O'Keefe, SE Samaraweera, CL van Eyk, CJ McLeod, ... Human Molecular Genetics 20 (19), 3757-3768, 2011 | 58 | 2011 |
Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs CL Van Eyk, LV O'Keefe, KT Lawlor, SE Samaraweera, CJ McLeod, ... Human molecular genetics 20 (14), 2783-2794, 2011 | 35 | 2011 |
Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases SE Samaraweera, LV O'Keefe, GR Price, DJ Venter, RI Richards Human Molecular Genetics 22 (14), 2811-2819, 2013 | 24 | 2013 |
Efficacy of combined CDK9/BET inhibition in preclinical models of MLL-rearranged acute leukemia H McCalmont, KL Li, L Jones, J Toubia, SC Bray, DA Casolari, C Mayoh, ... Blood Advances 4 (2), 296-300, 2020 | 23 | 2020 |
The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation AL Brown, DG Salerno, T Sadras, GA Engler, CH Kok, CR Wilkinson, ... Differentiation 83 (1), 47-59, 2012 | 23 | 2012 |
Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia VM Conn, M Gabryelska, J Toubia, K Kirk, L Gantley, JA Powell, G Cildir, ... Cancer cell 41 (7), 1309-1326. e10, 2023 | 22 | 2023 |
Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia KZY Maung, PJ Leo, M Bassal, DA Casolari, JX Gray, SC Bray, ... Blood Cancer Journal 8 (6), 50, 2018 | 20 | 2018 |
RNA pathogenesis via Toll-like receptor-activated inflammation in expanded repeat neurodegenerative diseases RI Richards, SE Samaraweera, CL Eyk, LV O’Keefe, CM Suter Frontiers in molecular neuroscience 6, 25, 2013 | 14 | 2013 |
Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology KT Lawlor, LV O’Keefe, SE Samaraweera, CL Van Eyk, RI Richards PLoS One 7 (6), e38516, 2012 | 12 | 2012 |
Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia MA Bassal, SE Samaraweera, K Lim, BA Benard, S Bailey, S Kaur, P Leo, ... Nature Communications 13 (1), 2614, 2022 | 11 | 2022 |
Childhood acute myeloid leukemia shows a high level of germline predisposition SE Samaraweera, PPS Wang, KL Li, DA Casolari, J Feng, M Pinese, ... Blood, The Journal of the American Society of Hematology 138 (22), 2293-2298, 2021 | 6 | 2021 |
Non-self mutation: double-stranded RNA elicits antiviral pathogenic response in a Drosophila model of expanded CAG repeat neurodegenerative diseases CL Eyk, SE Samaraweera, A Scott, DL Webber, DP Harvey, O Mecinger, ... Human molecular genetics 28 (18), 3000-3012, 2019 | 6 | 2019 |
Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia WL Kan, U Dhagat, KB Kaufmann, TR Hercus, TL Nero, AGX Zeng, ... Cancer Discovery 13 (8), 1922-1947, 2023 | 3 | 2023 |
Modeling and Analysis of Repeat RNA Toxicity in Drosophila SE Samaraweera, LV O’Keefe, CL Van Eyk, KT Lawlor, DT Humphreys, ... Tandem Repeats in Genes, Proteins, and Disease: Methods and Protocols, 173-192, 2013 | 3 | 2013 |
Metabolic Profiling of Adult Acute Myeloid Leukemia (AML) MA Bassal, P Leo, SE Samaraweera, KZY Maung, M Babic, P Venugopal, ... Blood 128 (22), 1684, 2016 | 2 | 2016 |
Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia MA Bassal, SE Samaraweera, K Lim, BA Benard, S Bailey, S Kaur, P Leo, ... Nature Communications 13, 2022 | 1 | 2022 |
Patterned behaviour and response to current treatments among children with Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum: a prospective study H Sudusinghe, S Pirabakaran, K Nanayakkara, J Seneviratne, ... AUSTRALASIAN JOURNAL OF DERMATOLOGY 59, 16-17, 2018 | 1 | 2018 |
Loss of stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML N Hassan, H Yi, B Malik, LC Gaspard-Boulinc, SEE Samaraweera, ... Blood Journal, blood. 2024024072, 2024 | | 2024 |
IDH Mutant Myeloid Neoplasms are Associated with Seronegative Rheumatoid Arthritis and Innate Immune Activation LE Hong, MD Wechalekar, M Kutyna, A Small, K Lim, C Thompson-Peach, ... Blood, 2024 | | 2024 |