| A pancreatic islet-specific microRNA regulates insulin secretion MN Poy, L Eliasson, J Krutzfeldt, S Kuwajima, X Ma, PE Macdonald, ... Nature 432 (7014), 226-230, 2004 | 2702 | 2004 |
| The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion PE MacDonald, W El-Kholy, MJ Riedel, AMF Salapatek, PE Light, ... Diabetes 51 (suppl_3), S434-S442, 2002 | 703 | 2002 |
| The cell biology of systemic insulin function VL Tokarz, PE MacDonald, A Klip Journal of Cell Biology 217 (7), 2273-2289, 2018 | 506 | 2018 |
| SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas JA Müller, R Groß, C Conzelmann, J Krüger, U Merle, J Steinhart, T Weil, ... Nature metabolism 3 (2), 149-165, 2021 | 474 | 2021 |
| Glucose-sensing mechanisms in pancreatic β-cells PE MacDonald, JW Joseph, P Rorsman Philosophical Transactions of the Royal Society B: Biological Sciences 360 …, 2005 | 463 | 2005 |
| Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets. CB Chan, PE MacDonald, MC Saleh, DC Johns, E Marbàn, MB Wheeler Diabetes 48 (7), 1482-1486, 1999 | 340 | 1999 |
| A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans PE MacDonald, YZD Marinis, R Ramracheya, A Salehi, X Ma, ... PLoS biology 5 (6), e143, 2007 | 312 | 2007 |
| Voltage-dependent K+ channels in pancreatic beta cells: Role, regulation and potential as therapeutic targets PE MacDonald, MB Wheeler Diabetologia 46, 1046-1062, 2003 | 307 | 2003 |
| Members of the Kv1 and Kv2 Voltage-Dependent K+ Channel Families Regulate Insulin Secretion PE MacDonald, XF Ha, J Wang, SR Smukler, AM Sun, HY Gaisano, ... Molecular endocrinology 15 (8), 1423-1435, 2001 | 241 | 2001 |
| Inhibition of Kv2. 1 voltage-dependent K+ channels in pancreatic β-cells enhances glucose-dependent insulin secretion PE MacDonald, S Sewing, J Wang, JW Joseph, SR Smukler, ... Journal of Biological Chemistry 277 (47), 44938-44945, 2002 | 212 | 2002 |
| Patch-seq links single-cell transcriptomes to human islet dysfunction in diabetes J Camunas-Soler, XQ Dai, Y Hang, A Bautista, J Lyon, K Suzuki, SK Kim, ... Cell metabolism 31 (5), 1017-1031. e4, 2020 | 209 | 2020 |
| β Cell tone is defined by proglucagon peptides through cAMP signaling ME Capozzi, B Svendsen, SE Encisco, SL Lewandowski, MD Martin, ... JCI insight 4 (5), 2019 | 203 | 2019 |
| Converting adult pancreatic islet α cells into β cells by targeting both Dnmt1 and Arx H Chakravarthy, X Gu, M Enge, X Dai, Y Wang, N Damond, C Downie, ... Cell metabolism 25 (3), 622-634, 2017 | 196 | 2017 |
| Transcript expression data from human islets links regulatory signals from genome-wide association studies for type 2 diabetes and glycemic traits to their downstream effectors M van de Bunt, JE Manning Fox, X Dai, A Barrett, C Grey, L Li, AJ Bennett, ... PLoS genetics 11 (12), e1005694, 2015 | 185 | 2015 |
| Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells M Ferdaoussi, X Dai, MV Jensen, R Wang, BS Peterson, C Huang, ... The Journal of clinical investigation 125 (10), 3847-3860, 2015 | 181 | 2015 |
| G protein-coupled receptor (GPR) 40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1 M Ferdaoussi, V Bergeron, B Zarrouki, J Kolic, J Cantley, J Fielitz, ... Diabetologia 55, 2682-2692, 2012 | 177 | 2012 |
| SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β-and α-cells B Kailey, M van de Bunt, S Cheley, PR Johnson, PE MacDonald, ... American journal of physiology-endocrinology and metabolism 303 (9), E1107-E1116, 2012 | 171 | 2012 |
| Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells PE MacDonald, M Braun, J Galvanovskis, P Rorsman Cell metabolism 4 (4), 283-290, 2006 | 167 | 2006 |
| Cystic fibrosis–related diabetes is caused by islet loss and inflammation NJ Hart, R Aramandla, G Poffenberger, C Fayolle, AH Thames, A Bautista, ... JCI insight 3 (8), 2018 | 165 | 2018 |
| Glucagon-Like Peptide-1 Receptor Activation Antagonizes Voltage-Dependent Repolarizing K+ Currents in β-Cells: A Possible Glucose-Dependent Insulinotropic … PE MacDonald, AMF Salapatek, MB Wheeler Diabetes 51 (suppl_3), S443-S447, 2002 | 149 | 2002 |
Herbert Gaisanouniversity of torontoVerified email at utoronto.ca
