| A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress P Pino, R Caldelari, B Mukherjee, J Vahokoski, N Klages, B Maco, ... Science 358 (6362), 522-528, 2017 | 136 | 2017 |
| An apicomplexan actin-binding protein serves as a connector and lipid sensor to coordinate motility and invasion D Jacot, N Tosetti, I Pires, J Stock, A Graindorge, YF Hung, H Han, ... Cell host & microbe 20 (6), 731-743, 2016 | 129 | 2016 |
| Crystal structure of triosephosphate isomerase complexed with 2-phosphoglycolate at 0.83-Å resolution I Kursula, RK Wierenga Journal of Biological Chemistry 278 (11), 9544-9551, 2003 | 121 | 2003 |
| Structural Differences Explain Diverse Functions of Plasmodium Actins J Vahokoski, SP Bhargav, A Desfosses, M Andreadaki, EP Kumpula, ... PLoS pathogens 10 (4), e1004091, 2014 | 85 | 2014 |
| High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain … P Kursula, I Kursula, M Massimi, YH Song, J Downer, WA Stanley, ... Journal of molecular biology 375 (1), 270-290, 2008 | 85 | 2008 |
| Structural and functional characterization of human peripheral nervous system myelin protein P2 V Majava, E Polverini, A Mazzini, R Nanekar, W Knoll, J Peters, F Natali, ... PLoS One 5 (4), e10300, 2010 | 76 | 2010 |
| Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum I Kursula, P Kursula, M Ganter, S Panjikar, K Matuschewski, H Schüler Structure 16 (11), 1638-1648, 2008 | 75 | 2008 |
| Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability S Pospich, EP Kumpula, J von der Ecken, J Vahokoski, I Kursula, ... Proceedings of the National Academy of Sciences 114 (40), 10636-10641, 2017 | 72 | 2017 |
| The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase AM Lambeir, J Backmann, J Ruiz‐Sanz, V Filimonov, JE Nielsen, ... European Journal of Biochemistry 267 (9), 2516-2524, 2000 | 71 | 2000 |
| Structure of Toxoplasma gondii coronin, an actin‐binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress J Salamun, JP Kallio, W Daher, D Soldati‐Favre, I Kursula The FASEB Journal 28 (11), 4729-4747, 2014 | 62 | 2014 |
| Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase I Kursula, M Salin, J Sun, BV Norledge, AM Haapalainen, NS Sampson, ... Protein Engineering Design and Selection 17 (4), 375, 2004 | 57 | 2004 |
| Structural determinants for ligand binding and catalysis of triosephosphate isomerase I Kursula, S Partanen, AM Lambeir, DM Antonov, K Augustyns, ... European Journal of Biochemistry 268 (19), 5189-5196, 2001 | 55 | 2001 |
| A neutralizing antibody against human DNA polymerase ε inhibits cellular but not SV40 DNA replication H Pospiech, I Kursula, W Abdel-Aziz, L Malkas, L Uitto, M Kastelli, ... Nucleic acids research 27 (19), 3799-3804, 1999 | 54 | 1999 |
| A unique profilin-actin interface is important for malaria parasite motility CA Moreau, SP Bhargav, H Kumar, KA Quadt, H Piirainen, L Strauss, ... PLoS pathogens 13 (5), e1006412, 2017 | 50 | 2017 |
| Atomic resolution view into the structure–function relationships of the human myelin peripheral membrane protein P2 S Ruskamo, RP Yadav, S Sharma, M Lehtimäki, S Laulumaa, S Aggarwal, ... Acta Crystallographica Section D: Biological Crystallography 70 (1), 165-176, 2014 | 50 | 2014 |
| The importance of the conserved Arg191-Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis I Kursula, S Partanen, AM Lambeir, RK Wierenga FEBS letters 518 (1-3), 39-42, 2002 | 46 | 2002 |
| Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility JL Green, RJ Wall, J Vahokoski, NA Yusuf, MAM Ridzuan, RR Stanway, ... Journal of Biological Chemistry 292 (43), 17857-17875, 2017 | 41 | 2017 |
| Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite BK Singh, JM Sattler, M Chatterjee, J Huttu, H Schüler, I Kursula Journal of Biological Chemistry 286 (32), 28256-28264, 2011 | 41 | 2011 |
| Structural and functional dissection of Toxoplasma gondii armadillo repeats only protein C Mueller, A Samoo, PM Hammoudi, N Klages, JP Kallio, I Kursula, ... Journal of cell science 129 (5), 1031-1045, 2016 | 36 | 2016 |
| Structure of the dimeric autoinhibited conformation of DAPK2, a pro-apoptotic protein kinase AK Patel, RP Yadav, V Majava, I Kursula, P Kursula Journal of Molecular Biology, 2011 | 34 | 2011 |
Petri KursulaUniversity of BergenVerified email at uib.no
