Sourav Das, PhD
Sourav Das, PhD
Senior Scientist, Cheminformatics, St. Jude Children's Research Hospital
Verified email at
Cited by
Cited by
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux
RE Lee, JG Hurdle, J Liu, DF Bruhn, T Matt, MS Scherman, PK Vaddady, ...
Nature medicine 20 (2), 152-158, 2014
Binding affinity prediction with property-encoded shape distribution signatures
S Das, MP Krein, CM Breneman
Journal of chemical information and modeling 50 (2), 298-308, 2010
Rapid comparison of protein binding site surfaces with property encoded shape distributions
S Das, A Kokardekar, CM Breneman
Journal of chemical information and modeling 49 (12), 2863-2872, 2009
Identification of potent, selective, and orally bioavailable small-molecule GSPT1/2 degraders from a focused library of cereblon modulators
G Nishiguchi, F Keramatnia, J Min, Y Chang, B Jonchere, S Das, M Actis, ...
Journal of Medicinal Chemistry 64 (11), 7296-7311, 2021
Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs
J Min, A Mayasundari, F Keramatnia, B Jonchere, SW Yang, J Jarusiewicz, ...
Angewandte Chemie International Edition 60 (51), 26663-26670, 2021
Current trends in virtual high throughput screening using ligand-based and structure-based methods
N Sukumar, S Das
Combinatorial chemistry & high throughput screening 14 (10), 872-888, 2011
Targeting histone demethylases in MYC-driven neuroblastomas with ciclopirox
J Yang, S Milasta, D Hu, AM AlTahan, RB Interiano, J Zhou, J Davidson, ...
Cancer research 77 (17), 4626-4638, 2017
Structure–activity relationships of spectinamide antituberculosis agents: a dissection of ribosomal inhibition and native efflux avoidance contributions
J Liu, DF Bruhn, RB Lee, Z Zheng, T Janusic, D Scherbakov, ...
ACS infectious diseases 3 (1), 72-88, 2017
Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer
PJ Slavish, L Chi, MK Yun, L Tsurkan, NE Martinez, B Jonchere, SC Chai, ...
Cancer research 80 (17), 3507-3518, 2020
ABCG2 requires a single aromatic amino acid to “clamp” substrates and inhibitors into the binding pocket
T Gose, T Shafi, Y Fukuda, S Das, Y Wang, A Allcock, AG McHarg, ...
FASEB journal: official publication of the Federation of American Societies …, 2020
Novel vitexin-inspired scaffold against leukemia
T Ling, W Lang, X Feng, S Das, J Maier, C Jeffries, A Shelat, F Rivas
European Journal of Medicinal Chemistry 146, 501-510, 2018
PESDserv: a server for high-throughput comparison of protein binding site surfaces
S Das, MP Krein, CM Breneman
Bioinformatics 26 (15), 1913-1914, 2010
Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes
J Qi, KG Virga, S Das, Y Zhao, MK Yun, SW White, RE Lee
Bioorganic & medicinal chemistry 19 (3), 1298-1305, 2011
Small molecule sequestration of the intrinsically disordered protein, p27Kip1, within soluble oligomers
LI Iconaru, S Das, A Nourse, AA Shelat, J Zuo, RW Kriwacki
Journal of molecular biology 433 (18), 167120, 2021
Development of a pterin-based fluorescent probe for screening dihydropteroate synthase
Y Zhao, D Hammoudeh, W Lin, S Das, MK Yun, Z Li, E Griffith, T Chen, ...
Bioconjugate Chemistry 22 (10), 2110-2117, 2011
Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in Mycobacterium tuberculosis
AE Grzegorzewicz, C Gee, S Das, J Liu, JM Belardinelli, V Jones, ...
ACS infectious diseases 6 (2), 195-204, 2019
Composition for reduction of trpa1 and trpv1 sensations
JC Haught, K Sreekrishna, S Das, IISH HOKE, TW Coffindaffer, KA Bakes, ...
US Patent App. 13/873,749, 2013
Synthesis and evaluation of colletoic acid core derivatives
T Ling, LN Gautam, E Griffith, S Das, W Lang, WR Shadrick, A Shelat, ...
European Journal of Medicinal Chemistry 110, 126-132, 2016
17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma
S Singh, A Abu-Zaid, W Lin, J Low, A Abdolvahabi, H Jin, Q Wu, B Cooke, ...
Iscience 24 (1), 2021
Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents
T Ling, J Maier, S Das, A Budhraja, R Bassett, MB Potts, A Shelat, ...
European Journal of Medicinal Chemistry 164, 391-398, 2019
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