Mikael H Elias
Mikael H Elias
Other namesMikael Elias
Associate Professor of Biochemistry, University of Minnesota
Verified email at - Homepage
Cited by
Cited by
Interference in bacterial quorum sensing: a biopharmaceutical perspective
B Rémy, S Mion, L Plener, M Elias, E Chabrière, D Daudé
Frontiers in pharmacology 9, 203, 2018
The molecular basis of phosphate discrimination in arsenate-rich environments
M Elias, A Wellner, K Goldin-Azulay, E Chabriere, JA Vorholt, TJ Erb, ...
Nature 491 (7422), 134-137, 2012
The universality of enzymatic rate–temperature dependency
M Elias, G Wieczorek, S Rosenne, DS Tawfik
Trends in Biochemical Sciences 39 (1), 1-7, 2014
Structural basis for natural lactonase and promiscuous phosphotriesterase activities
M Elias, J Dupuy, L Merone, L Mandrich, E Porzio, S Moniot, D Rochu, ...
Journal of molecular biology 379 (5), 1017-1028, 2008
What makes a protein fold amenable to functional innovation? Fold polarity and stability trade-offs
E Dellus-Gur, A Toth-Petroczy, M Elias, DS Tawfik
Journal of molecular biology 425 (14), 2609-2621, 2013
Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1
M Ben-David, M Elias, JJ Filippi, E Duñach, I Silman, JL Sussman, ...
Journal of molecular biology 418 (3-4), 181-196, 2012
Biotechnological applications of quorum quenching enzymes
J Bzdrenga, D Daude, B Remy, P Jacquet, L Plener, M Elias, E Chabriere
Chemico-biological interactions 267, 104-115, 2017
Divergence and convergence in enzyme evolution: parallel evolution of paraoxonases from quorum-quenching lactonases
M Elias, DS Tawfik
Journal of Biological Chemistry 287 (1), 11-20, 2012
Effect of Quorum Quenching Lactonase in Clinical Isolates of Pseudomonas aeruginosa and Comparison with Quorum Sensing Inhibitors
A Guendouze, L Plener, J Bzdrenga, P Jacquet, B Rémy, M Elias, ...
Frontiers in Microbiology 8, 227, 2017
Negative epistasis and evolvability in TEM-1 β-lactamase—the thin line between an enzyme's conformational freedom and disorder
E Dellus-Gur, M Elias, E Caselli, F Prati, MLM Salverda, JAGM De Visser, ...
Journal of molecular biology 427 (14), 2396-2409, 2015
Characterisation of the organophosphate hydrolase catalytic activity of SsoPox
J Hiblot, G Gotthard, E Chabriere, M Elias
Scientific reports 2 (1), 779, 2012
Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumonia
S Hraiech, J Hiblot, J Lafleur, H Lepidi, L Papazian, JM Rolain, D Raoult, ...
PLoS One 9 (10), e107125, 2014
Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes
P Jacquet, D Daudé, J Bzdrenga, P Masson, M Elias, E Chabrière
Environmental Science and Pollution Research 23, 8200-8218, 2016
Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox
J Hiblot, G Gotthard, M Elias, E Chabriere
PLoS One 8 (9), e75272, 2013
Structural and Enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus
J Hiblot, G Gotthard, E Chabriere, M Elias
Public Library of Science 7 (10), e47028, 2012
Directed evolution of sulfotransferases and paraoxonases by ancestral libraries
U Alcolombri, M Elias, DS Tawfik
Journal of molecular biology 411 (4), 837-853, 2011
Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme
M Ben-David, G Wieczorek, M Elias, I Silman, JL Sussman, DS Tawfik
Journal of molecular biology 425 (6), 1028-1038, 2013
Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus
P Del Vecchio, M Elias, L Merone, G Graziano, J Dupuy, L Mandrich, ...
Extremophiles 13, 461-470, 2009
Elucidation of the phosphate binding mode of DING proteins revealed by subangstrom X-ray crystallography
D Liebschner, M Elias, S Moniot, B Fournier, K Scott, C Jelsch, B Guillot, ...
Journal of the American Chemical Society 131 (22), 7879-7886, 2009
Structural and Enzymatic Characterization of the Phosphotriesterase OPHC2 from Pseudomonas pseudoalcaligenes
G Gotthard, J Hiblot, D Gonzalez, M Elias, E Chabriere
PLoS One 8 (11), e77995, 2013
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