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Ruben Bartholomäus
Ruben Bartholomäus
Verified email at pharma.ethz.ch
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Cited by
Year
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2
SM Jackson, I Manolaridis, J Kowal, M Zechner, NMI Taylor, M Bause, ...
Nature structural & molecular biology 25 (4), 333-340, 2018
3012018
Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake
A Chicca, S Nicolussi, R Bartholomäus, M Blunder, A Aparisi Rey, ...
Proceedings of the National Academy of Sciences 114 (25), E5006-E5015, 2017
972017
Complex surface chemistry of an otherwise inert solvent molecule: Tetrahydrofuran on Si (001)
G Mette, M Reutzel, R Bartholomäus, S Laref, R Tonner, M Dürr, U Koert, ...
ChemPhysChem 15 (17), 3725-3728, 2014
422014
Real-space adsorption studies of cyclooctyne on Si (0 0 1)
G Mette, M Dürr, R Bartholomäus, U Koert, U Höfer
Chemical Physics Letters 556, 70-76, 2013
352013
Tracing binding modes in hit‐to‐lead optimization: chameleon‐like poses of aspartic protease inhibitors
M Kuhnert, H Köster, R Bartholomäus, AY Park, A Shahim, A Heine, ...
Angewandte Chemie International Edition 54 (9), 2849-2853, 2015
332015
Total synthesis of the postulated structure of fulicineroside
R Bartholomäus, F Dommershausen, M Thiele, NS Karanjule, K Harms, ...
Chemistry–A European Journal 19 (23), 7423-7436, 2013
282013
Isolation, characterization, and nuclease activity of biologically relevant chromium (V) complexes with monosaccharides and model diols. Likely intermediates in chromium …
R Bartholomäus, JA Irwin, L Shi, SM Smith, A Levina, PA Lay
Inorganic Chemistry 52 (8), 4282-4292, 2013
252013
Synthesis and Characterization of a Chromium(V) cis-1,2-Cyclohexanediolato Complex: A Model of Reactive Intermediates in Chromium-Induced Cancers
R Bartholomäus, K Harms, A Levina, PA Lay
Inorganic Chemistry 51 (21), 11238-11240, 2012
182012
Synthesis of the AB‐Ring Pyranolactone Substructure of Granaticin A
R Bartholomäus, J Bachmann, C Mang, LO Haustedt, K Harms, U Koert
European Journal of Organic Chemistry 2013 (1), 180-190, 2013
122013
Total synthesis of the endocannabinoid uptake inhibitor guineensine and SAR studies
R Bartholomäus, S Nicolussi, A Baumann, M Rau, AC Simão, J Gertsch, ...
ChemMedChem 14 (17), 1590-1596, 2019
72019
Synthesis and biological evaluation of endocannabinoid uptake inhibitors derived from WOBE437
P Mäder, R Bartholomäus, S Nicolussi, A Baumann, M Weis, A Chicca, ...
ChemMedChem 16 (1), 145-154, 2021
62021
Chamäleon‐artige Bindungsmodi in der Leitstrukturoptimierung: wechselnde Bindungsgeometrien bei Aspartylprotease‐Inhibitoren
M Kuhnert, H Köster, R Bartholomäus, AY Park, A Shahim, A Heine, ...
Angewandte Chemie 127 (9), 2891-2896, 2015
22015
Front Cover: Total Synthesis of the Endocannabinoid Uptake Inhibitor Guineensine and SAR Studies (ChemMedChem 17/2019)
R Bartholomäus, S Nicolussi, A Baumann, M Rau, AC Simão, J Gertsch, ...
ChemMedChem 14 (17), 1573-1573, 2019
2019
Structural basis of inhibition of ABCG2 by small molecules
SM Jackson, I Manolaridis, J Kowal, M Zechner, M Bause, S Bauer, ...
NCCR Transcure 7th Site Visit, 2017
2017
Synthese der AB-Ring-Substruktur von Granaticin A und Totalsynthese von Fulicinerosid
R Bartholomäus
Philipps-Universität Marburg, 2013
2013
Synthese und Struktur-Wirkungsbeziehungen substituierter Thiophene als neuartige Leitstrukturen zur Inhibition von Plasmepsin II und IV
R Bartholomäus
2007
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