Aberrant methylation of the negative regulators RASSFIA, SHP‐1 and SOCS‐1 in myelodysplastic syndromes and acute myeloid leukaemia MF Johan, DT Bowen, ME Frew, AC Goodeve, JT Reilly British journal of haematology 129 (1), 60-65, 2005 | 111 | 2005 |
Thymoquinone, as a novel therapeutic candidate of cancers B Almajali, HAN Al-Jamal, WRW Taib, I Ismail, MF Johan, AA Doolaanea, ... Pharmaceuticals 14 (4), 369, 2021 | 73 | 2021 |
Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute … HAN Al-Jamal, SA Mat Jusoh, R Hassan, MF Johan BMC cancer 15, 1-11, 2015 | 62 | 2015 |
Enhanced induction of cell cycle arrest and apoptosis via the mitochondrial membrane potential disruption in human U87 malignant glioma cells by aloe emodin S Ismail, K Haris, ARI Abdul Ghani, JM Abdullah, MF Johan, ... Journal of Asian natural products research 15 (9), 1003-1012, 2013 | 45 | 2013 |
Growth inhibitory effects of crude pomegranate peel extract on chronic myeloid leukemia, K562 cells MJS Asmaa, AJH Ali, JM Farid, S Azman International Journal of Applied and Basic Medical Research 5 (2), 100-105, 2015 | 44 | 2015 |
JAK2 V617F Mutation is uncommon in chronic myelomonocytic leukaemia MF Johan, AC Goodeve, DT Bowen, ME Frew, JT Reilly British journal of haematology 130 (6), 968-968, 2005 | 42 | 2005 |
Silencing of suppressor of cytokine signaling-3 due to methylation results in phosphorylation of STAT3 in imatinib resistant BCR-ABL positive chronic myeloid leukemia cells HAN Al-Jamal, SAM Jusoh, AC Yong, JM Asan, R Hassan, MF Johan Asian Pacific Journal of Cancer Prevention 15 (11), 4555-4561, 2014 | 40 | 2014 |
Mutations in PTPN11 are uncommon in adult myelodysplastic syndromes and acute myeloid leukaemia MF Johan, DT Bowen, ME Frew, AC Goodeve, GA Wilson, IR Peake, ... British journal of haematology 124 (6), 843-844, 2004 | 37 | 2004 |
Guidelines for nucleic acid detection and analysis in hematological disorders F Rosline Hassan MMED, SG Dip, SK Cheong The Malaysian journal of pathology 37 (2), 165, 2015 | 31 | 2015 |
The first Malay database toward the ethnic-specific target molecular variation H Halim-Fikri, A Etemad, AZA Latif, AF Merican, AA Baig, AA Annuar, ... BMC research notes 8, 1-6, 2015 | 29 | 2015 |
Next-generation sequencing (NGS) and third-generation sequencing (TGS) for the diagnosis of thalassemia S Hassan, R Bahar, MF Johan, EK Mohamed Hashim, WZ Abdullah, ... Diagnostics 13 (3), 373, 2023 | 27 | 2023 |
Apoptosis induction in MV4-11 and K562 human leukemic cells by Pereskia sacharosa (Cactaceae) leaf crude extract MJS Asmaa, HAN Al-Jamal, CY Ang, JM Asan, A Seeni, MF Johan Asian Pacific Journal of Cancer Prevention 15 (1), 475-481, 2014 | 25 | 2014 |
Gene expression profiling and protein analysis reveal suppression of the C-Myc oncogene and inhibition JAK/STAT and PI3K/AKT/mTOR signaling by thymoquinone in acute myeloid … B Almajali, MF Johan, AS Al-Wajeeh, WR Wan Taib, I Ismail, ... Pharmaceuticals 15 (3), 307, 2022 | 24 | 2022 |
Epigenetic Insights and Potential Modifiers as Therapeutic Targets in β–Thalassemia NA Zakaria, MA Islam, WZ Abdullah, R Bahar, AA Mohamed Yusoff, ... Biomolecules 11 (5), 755, 2021 | 23 | 2021 |
Multiplex amplification refractory mutation system (MARMS) for the detection of β-globin gene mutations among the transfusion-dependent β-thalassemia Malay patients in Kelantan … S Hanafi, R Hassan, R Bahar, WZ Abdullah, MF Johan, ND Rashid, ... American journal of blood research 4 (1), 33, 2014 | 23 | 2014 |
Evaluation of serological transfusion-transmitted viral diseases and mutliplex nucleic acid testing in malaysian blood donors SG Yaseen, SA Ahmed, MF Johan, R Kiron, AM Daher Transfusion and Apheresis Science 49 (3), 647-651, 2013 | 22 | 2013 |
Horizontal well optimization with inflow control devices (ICDs) application in heterogeneous and dipping gas-capped oil reservoirs AK Rahimah, NM Azrul, KF GordonGoh, AN Asyikin, E Leung, M Johan SPE Annual Technical Conference and Exhibition?, SPE-133336-MS, 2010 | 21 | 2010 |
Thymoquinone suppresses cell proliferation and enhances apoptosis of HL60 leukemia cells through re-expression of JAK/STAT negative regulators B Almajali, HAN Al-Jamal, WRW Taib, I Ismail, MF Johan, WN Ibrahim, ... Asian Pacific Journal of Cancer Prevention: APJCP 22 (3), 879, 2021 | 20 | 2021 |
Thymoquinone Inhibits Growth of Acute Myeloid Leukemia Cells through Reversal SHP-1 and SOCS-3 Hypermethylation: In Vitro and In Silico Evaluation FA Al-Rawashde, MF Johan, WRW Taib, I Ismail, SATT Johari, B Almajali, ... Pharmaceuticals 14 (12), 1287, 2021 | 18 | 2021 |
Thymoquinone induces downregulation of BCR-ABL/JAK/STAT pathway and apoptosis in K562 leukemia cells FA Al-Rawashde, WRW Taib, I Ismail, MF Johan, AS Al-Wajeeh, ... Asian Pacific Journal of Cancer Prevention: APJCP 22 (12), 3959, 2021 | 18 | 2021 |