Lai Yue Angeline Chan
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Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds
LY Chan, S Gunasekera, ST Henriques, NF Worth, SJ Le, RJ Clark, ...
Blood, The Journal of the American Society of Hematology 118 (25), 6709-6717, 2011
High-affinity cyclic peptide matriptase inhibitors
P Quimbar, U Malik, CP Sommerhoff, Q Kaas, LY Chan, YH Huang, ...
Journal of Biological Chemistry 288 (19), 13885-13896, 2013
Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis
JS Mylne, LY Chan, AH Chanson, NL Daly, H Schaefer, TL Bailey, ...
The Plant Cell 24 (7), 2765-2778, 2012
Cyclotides as grafting frameworks for protein engineering and drug design applications
AG Poth, LY Chan, DJ Craik
Peptide Science 100 (5), 480-491, 2013
Semienzymatic cyclization of disulfide-rich peptides using Sortase A
X Jia, S Kwon, CIA Wang, YH Huang, LY Chan, CC Tan, KJ Rosengren, ...
Journal of Biological Chemistry 289 (10), 6627-6638, 2014
Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases
MA Jackson, EK Gilding, T Shafee, KS Harris, Q Kaas, S Poon, K Yap, ...
Nature communications 9 (1), 1-12, 2018
Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia
MJ Smout, J Sotillo, T Laha, A Papatpremsiri, G Rinaldi, RN Pimenta, ...
PLoS Pathog 11 (10), e1005209, 2015
Isolation and characterization of cytotoxic cyclotides from Viola philippica
W He, LY Chan, G Zeng, NL Daly, DJ Craik, N Tan
Peptides 32 (8), 1719-1723, 2011
Cyclization of the Antimicrobial Peptide Gomesin with Native Chemical Ligation: Influences on Stability and Bioactivity
LY Chan, VM Zhang, Y Huang, NC Waters, PS Bansal, DJ Craik, NL Daly
ChemBioChem 14 (5), 617-624, 2013
Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy
LY Chan, DJ Craik, NL Daly
Scientific reports 6 (1), 1-13, 2016
Isolation and characterization of peptides from Momordica cochinchinensis seeds
LY Chan, CKL Wang, JM Major, KP Greenwood, RJ Lewis, DJ Craik, ...
Journal of natural products 72 (8), 1453-1458, 2009
Using the MCoTI-II cyclotide scaffold to design a stable cyclic peptide antagonist of SET, a protein overexpressed in human cancer
C D’Souza, ST Henriques, CK Wang, O Cheneval, LY Chan, NJ Bokil, ...
Biochemistry 55 (2), 396-405, 2016
Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium
K Himeno, KJ Rosengren, T Inoue, RH Perez, ML Colgrave, HS Lee, ...
Biochemistry 54 (31), 4863-4876, 2015
Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration
LY Chan, DJ Craik, NL Daly
Bioscience reports 35 (6), e00270, 2015
A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies
MH Cardoso, ES Cândido, LY Chan, M Der Torossian Torres, ...
ACS infectious diseases 4 (12), 1727-1736, 2018
Redesigned spider peptide with improved antimicrobial and anticancer properties
S Troeira Henriques, N Lawrence, S Chaousis, AS Ravipati, O Cheneval, ...
ACS Chemical Biology 12 (9), 2324-2334, 2017
A new family of cystine knot peptides from the seeds of Momordica cochinchinensis
LY Chan, W He, N Tan, G Zeng, DJ Craik, NL Daly
Peptides 39, 29-35, 2013
A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors
J Du, K Yap, LY Chan, FBH Rehm, FY Looi, AG Poth, EK Gilding, Q Kaas, ...
Nature communications 11 (1), 1-11, 2020
Short cationic peptide derived from Archaea with dual antibacterial properties and anti-infective potential
ES Cândido, MH Cardoso, LY Chan, MDT Torres, KGN Oshiro, ...
ACS infectious diseases 5 (7), 1081-1086, 2019
The role of disulfide bonds in structure and activity of chlorotoxin
PG Ojeda, LY Chan, AG Poth, CK Wang, DJ Craik
Future Medicinal Chemistry 6 (15), 1617-1628, 2014
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