De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 964* | 2023 |
Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 353* | 2022 |
Protein sequence design by conformational landscape optimization C Norn, BIM Wicky, D Juergens, S Liu, D Kim, D Tischer, B Koepnick, ... Proceedings of the National Academy of Sciences 118 (11), e2017228118, 2021 | 189* | 2021 |
De novo design of high-affinity binders of bioactive helical peptides S Vázquez Torres, PJY Leung, P Venkatesh, ID Lutz, F Hink, HH Huynh, ... Nature 626 (7998), 435-442, 2024 | 81* | 2024 |
Design of stimulus-responsive two-state hinge proteins F Praetorius, PJY Leung, MH Tessmer, A Broerman, C Demakis, ... Science 381 (6659), 754-760, 2023 | 30 | 2023 |
Zero‐shot mutation effect prediction on protein stability and function using RoseTTAFold S Mansoor, M Baek, D Juergens, JL Watson, D Baker Protein Science 32 (11), e4780, 2023 | 28* | 2023 |
HIV detection from human serum with paper-based isotachophoretic RNA extraction and reverse transcription recombinase polymerase amplification AT Bender, BP Sullivan, JY Zhang, DC Juergens, L Lillis, DS Boyle, ... Analyst 146 (9), 2851-2861, 2021 | 28 | 2021 |
De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles L An, M Said, L Tran, S Majumder, I Goreshnik, GR Lee, D Juergens, ... bioRxiv, 2023 | 9* | 2023 |
Computational design of serine hydrolases A Lauko, SJ Pellock, I Anischanka, KH Sumida, D Juergens, W Ahern, ... bioRxiv, 2024 | 2 | 2024 |
De novo protein design with deep learning D Juergens | | 2024 |
Parametrically guided design of beta barrels and transmembrane nanopores using deep learning DE Kim, JL Watson, D Juergens, S Majumder, SR Gerben, A Kang, ... bioRxiv, 2024 | | 2024 |
Accurate de novo design of high-affinity protein binding macrocycles using deep learning S Rettie, D Juergens, V Adebomi, YF Bueso, Q Zhao, A Leveille, A Liu, ... bioRxiv, 2024.11. 18.622547, 2024 | | 2024 |
Scaffolding protein functional sites using deep learning D Baker, J Wang, R Ragotte, L Milles, JL Watson, D Juergens, S Lisanza, ... US Patent App. 18/339,519, 2023 | | 2023 |
Transformer-based models for protein structure generation A Bhatnagar, D Juergens, P Rangarajan | | |