Phenotypic, functional, and plasticity features of classical and alternatively activated human macrophages AA Tarique, J Logan, E Thomas, PG Holt, PD Sly, E Fantino American journal of respiratory cell and molecular biology 53 (5), 676-688, 2015 | 579 | 2015 |
The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor IS Lucet, E Fantino, M Styles, R Bamert, O Patel, SE Broughton, M Walter, ... Blood 107 (1), 176-183, 2006 | 320 | 2006 |
CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms JW Tyner, TG Bumm, J Deininger, L Wood, KJ Aichberger, MM Loriaux, ... Blood, The Journal of the American Society of Hematology 115 (25), 5232-5240, 2010 | 270 | 2010 |
Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains NK Williams, RS Bamert, O Patel, C Wang, PM Walden, AF Wilks, ... Journal of molecular biology 387 (1), 219-232, 2009 | 257 | 2009 |
Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder? KG Chandy, E Fantino, O Wittekindt, K Kalman, LL Tong, TH Ho, ... Molecular psychiatry 3 (1), 32-37, 1998 | 254 | 1998 |
CYT387, a selective JAK1/JAK2 inhibitor: in vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients A Pardanani, T Lasho, G Smith, CJ Burns, E Fantino, A Tefferi Leukemia 23 (8), 1441-1445, 2009 | 237 | 2009 |
Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. DA Keys, BS Lee, JA Dodd, TT Nguyen, L Vu, E Fantino, LM Burson, ... Genes & development 10 (7), 887-903, 1996 | 196 | 1996 |
Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy KM Spann, E Baturcam, J Schagen, C Jones, CP Straub, FM Preston, ... Thorax 69 (10), 918-925, 2014 | 101 | 2014 |
hKCa3/KCNN3 potassium channel gene: association of longer CAG repeats with schizophrenia in Israeli Ashkenazi Jews, expression in human tissues and localization to chromosome 1q21 V Dror, E Shamir, S Ghanshani, R Kimhi, M Swartz, Y Barak, R Weizman, ... Molecular psychiatry 4 (3), 254-260, 1999 | 97 | 1999 |
The 2.7 Å crystal structure of the autoinhibited human c-Fms kinase domain M Walter, IS Lucet, O Patel, SE Broughton, R Bamert, NK Williams, ... Journal of molecular biology 367 (3), 839-847, 2007 | 81 | 2007 |
Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs) CJ Burns, DG Bourke, L Andrau, X Bu, SA Charman, AC Donohue, ... Bioorganic & medicinal chemistry letters 19 (20), 5887-5892, 2009 | 80 | 2009 |
CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis AA Tarique, PD Sly, PG Holt, A Bosco, RS Ware, J Logan, SC Bell, ... Journal of Cystic Fibrosis 16 (4), 475-482, 2017 | 73 | 2017 |
Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia T Bowen, CA Guy, N Craddock, AG Cardno, NM Williams, G Spurlock, ... Molecular psychiatry 3 (3), 266-269, 1998 | 73 | 1998 |
TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kγ for suppression of inflammatory responses L Luo, AA Wall, SJ Tong, Y Hung, Z Xiao, AA Tarique, PD Sly, E Fantino, ... Cell reports 24 (11), 3033-3044, 2018 | 71 | 2018 |
Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children JC Brealey, KJ Chappell, S Galbraith, E Fantino, J Gaydon, S Tozer, ... Respirology 23 (2), 220-227, 2018 | 64 | 2018 |
Reduced epidermal growth factor receptor expression in hypohidrotic ectodermal dysplasia and Tabby mice. GA Vargas, E Fantino, C George-Nascimento, JJ Gargus, HT Haigler The Journal of clinical investigation 97 (11), 2426-2432, 1996 | 53 | 1996 |
Crystal structure of human Janus Kinase 2 (JAK2) and uses thereof AF Wilks, CJ Burns, E Fantino, I Lucet, J Rossjohn, ML Styles US Patent 7,593,820, 2009 | 52 | 2009 |
Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex MJ Smith, RA Sharples, G Evin, CA McLean, B Dean, G Pavey, E Fantino, ... Molecular brain research 127 (1-2), 128-135, 2004 | 45 | 2004 |
Lack of linkage or association between schizophrenia and the polymorphic trinucleotide repeat within the KCNN3 gene on chromosome 1q21 SE Antonarakis, JL Blouin, VK Lasseter, C Gehrig, U Radhakrishna, ... American journal of medical genetics 88 (4), 348-351, 1999 | 44 | 1999 |
Protein kinase signalling A Wilks, J Atkin, E Fantino US Patent App. 10/470,957, 2004 | 43 | 2004 |