Jörg Menche

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Albert-László BarabásiNortheastern University, Harvard Medical SchoolVerified email at neu.edu
Amitabh SharmaAssistant Professor of Medicine, Harvard Medical SchoolVerified email at channing.harvard.edu
Susan Dina GhiassianScipher MedicineVerified email at sciphermedicine.com
Marc VidalProfessor of Genetics, Harvard Medical SchoolVerified email at dfci.harvard.edu
Maksim KitsakSenior Assistant Professor, Faculty of Electrical Engineering, Mathematics and Computer Science, TUVerified email at tudelft.nl
Joseph LoscalzoProfessor of Medicine, Harvard Medical SchoolVerified email at partners.org
Emre GuneyCTO, Head of Discovery and Data Science at STALICLAVerified email at stalicla.com
Michael CalderaProxygenVerified email at proxygen.com
Loan VulliardMax Perutz LabsVerified email at cemm.oeaw.ac.at
Stefan KubicekCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesVerified email at cemm.oeaw.ac.at
Ed SilvermanVerified email at channing.harvard.edu
Xuezhong ZhouBeijing Jiaotong UniversityVerified email at bjtu.edu.cn
Christoph BockCeMM Research Center for Molecular Medicine & Medical University of Vienna, AustriaVerified email at bock.name
Joanna LoizouDirector of Translational Medicine, Early Oncology, AstraZenecaVerified email at astrazeneca.com
Kaan BoztugCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesVerified email at cemm.oeaw.ac.at
Harald H.H.W. SchmidtProfessor & Chair of Pharmacology and Personalised Medicine, University of MaastrichtVerified email at maastrichtuniversity.nl
Radu DobrinBristol-Myers Squibb CoVerified email at mssm.edu
Frederic BaribaudJanssen R&DVerified email at its.jnj.com
Michel OwusuPhD student, CeMMVerified email at cemm.oeaw.ac.at
Marc WiednerCeMMVerified email at cemm.oeaw.ac.at

Jörg Menche

University of Vienna, Max Perutz Labs

Verified email at univie.ac.at - Homepage

Network Medicine Systems Biology Computational Biology Network Science Virtual Reality


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A proteome-scale map of the human interactome network T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ... Cell 159 (5), 1212-1226, 2014	1326	2014
Uncovering disease-disease relationships through the incomplete interactome J Menche, A Sharma, M Kitsak, SD Ghiassian, M Vidal, J Loscalzo, ... Science 347 (6224), 1257601, 2015	1254	2015
Human symptoms–disease network XZ Zhou, J Menche, AL Barabási, A Sharma Nature communications 5 (1), 4212, 2014	603	2014
Canonical Genetic Signatures of the Adult Human Brain M Hawrylycz, JA Miller, V Menon, D Feng, T Dolbeare, ... Nature Neuroscience, 2015	472	2015
Network-based in silico drug efficacy screening E Guney, J Menche, M Vidal, AL Barábasi Nature communications 7 (1), 10331, 2016	417	2016
A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome SD Ghiassian, J Menche, AL Barabási PLoS computational biology 11 (4), e1004120, 2015	337	2015
Assessment of network module identification across complex diseases S Choobdar, ME Ahsen, J Crawford, M Tomasoni, T Fang, D Lamparter, ... Nature methods 16 (9), 843-852, 2019	213*	2019
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma A Sharma, J Menche, CC Huang, T Ort, X Zhou, M Kitsak, N Sahni, ... Human molecular genetics 24 (11), 3005-3020, 2015	181	2015
Tissue specificity of human disease module M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, ... Scientific reports 6 (1), 35241, 2016	99	2016
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers S Schick, AF Rendeiro, K Runggatscher, A Ringler, B Boidol, M Hinkel, ... Nature genetics 51 (9), 1399-1410, 2019	90	2019
Interactome-based approaches to human disease M Caldera, P Buphamalai, F Müller, J Menche Current Opinion in Systems Biology 3, 88-94, 2017	90	2017
Endophenotype network models: common core of complex diseases SD Ghiassian, J Menche, DI Chasman, F Giulianini, R Wang, P Ricchiuto, ... Scientific reports 6 (1), 1-13, 2016	76	2016
Plasticity of the Cullin-RING ligase repertoire shapes sensitivity to ligand-induced protein degradation C Mayor-Ruiz, MG Jaeger, S Bauer, M Brand, C Sin, A Hanzl, AC Mueller, ... Molecular cell 75 (4), 849-858. e8, 2019	68	2019
Type I interferon signaling disrupts the hepatic urea cycle and alters systemic metabolism to suppress T cell function A Lercher, A Bhattacharya, AM Popa, M Caldera, MF Schlapansky, ... Immunity 51 (6), 1074-1087. e9, 2019	62	2019
Asymptotic properties of degree-correlated scale-free networks J Menche, A Valleriani, R Lipowsky Physical Review E 81 (4), 046103, 2010	58	2010
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation S Sdelci, AF Rendeiro, P Rathert, W You, JMG Lin, A Ringler, G Hofstätter, ... Nature genetics 51 (6), 990-998, 2019	56	2019
Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms F Schischlik, R Jäger, F Rosebrock, E Hug, M Schuster, R Holly, E Fuchs, ... Blood, The Journal of the American Society of Hematology 134 (2), 199-210, 2019	55	2019
Integrating personalized gene expression profiles into predictive disease-associated gene pools J Menche, E Guney, A Sharma, PJ Branigan, MJ Loza, F Baribaud, ... NPJ systems biology and applications 3 (1), 10, 2017	55	2017
Non-classical monocytes as mediators of tissue destruction in arthritis A Puchner, V Saferding, M Bonelli, Y Mikami, M Hofmann, JS Brunner, ... Annals of the rheumatic diseases 77 (10), 1490-1497, 2018	54	2018
B cell–activating factor neutralization aggravates atherosclerosis D Tsiantoulas, AP Sage, L Göderle, M Ozsvar-Kozma, D Murphy, ... Circulation 138 (20), 2263-2273, 2018	50	2018

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