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Alexander Robert Melrose
Alexander Robert Melrose
Senior Research Assistant, Oregon Health & Science University
Verified email at ohsu.edu
Title
Cited by
Cited by
Year
Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs
Ö Babur, AR Melrose, JM Cunliffe, J Klimek, J Pang, ALI Sepp, ...
Blood, The Journal of the American Society of Hematology 136 (20), 2346-2358, 2020
672020
Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function
TJ Zheng, ER Lofurno, AR Melrose, HHS Lakshmanan, J Pang, ...
American Journal of Physiology-Cell Physiology 320 (5), C902-C915, 2021
302021
Revised model of the tissue factor pathway of thrombin generation: role of the feedback activation of FXI
HHS Lakshmanan, A Estonilo, SE Reitsma, AR Melrose, J Subramanian, ...
Journal of Thrombosis and Haemostasis 20 (6), 1350-1363, 2022
162022
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function
I Parra-Izquierdo, AR Melrose, J Pang, HHS Lakshmanan, SE Reitsma, ...
Platelets 33 (3), 404-415, 2022
162022
Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets
ST Yunga, AJ Gower, AR Melrose, MK Fitzgerald, A Rajendran, ...
Journal of Thrombosis and Haemostasis 20 (6), 1437-1450, 2022
142022
The toll-like receptor 2 ligand Pam2CSK4 activates platelet nuclear factor-κB and Bruton’s tyrosine kinase signaling to promote platelet-endothelial cell interactions
I Parra-Izquierdo, HHS Lakshmanan, AR Melrose, J Pang, TJ Zheng, ...
Frontiers in immunology 12, 729951, 2021
132021
The basement membrane protein nidogen-1 supports platelet adhesion and activation
HHS Lakshmanan, AR Melrose, ALI Sepp, A Mitrugno, ATP Ngo, ...
Platelets 32 (3), 424-428, 2021
102021
Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity
TJ Zheng, TCL Kohs, PA Mueller, J Pang, SE Reitsma, I Parra-Izquierdo, ...
Blood Advances 7 (8), 1366-1378, 2023
72023
Platelet reactivity and platelet count in women with iron deficiency treated with intravenous iron
BK Elstrott, HHS Lakshmanan, AR Melrose, KR Jordan, KL Martens, ...
Research and Practice in Thrombosis and Haemostasis 6 (2), e12692, 2022
72022
Identification, Quantification, and System Analysis of Protein N‐ε Lysine Methylation in Anucleate Blood Platelets
AD Rocheleau, AR Melrose, JM Cunliffe, J Klimek, Ö Babur, ...
Proteomics 19 (11), 1900001, 2019
72019
Tyrosine Kinase Inhibitors (TKIs) Targeting Syk and BTK Signaling Differentially Affect PI3K Signalosome Organization and Platelet Function
T Zheng, ER Lofurno, S Elgamal, AR Melrose, J Pang, JJ Shatzel, ...
Blood 134, 2074, 2019
12019
PB0885 β-amyloid Peptide Aβ40 Stimulates Glycoprotein Receptor GPVI Signaling to Generate Procoagulant Platelets
Y Zhang, A Melrose, J Pang, O McCarty, J Aslan
Research and Practice in Thrombosis and Haemostasis 7, 101622, 2023
2023
PB0883 Defining the Role of Hepcidin and Ferroportin Interactions in Regulating Platelet Function
K Martens, A Melrose, C Yang, M Geffert, J Lo, J Shatzel, J Aslan
Research and Practice in Thrombosis and Haemostasis 7, 101620, 2023
2023
PB0421 Phosphoproteomics and Systems Analysis Reveal Protein Kinase C Theta (PKCfɵ) Signaling Events Associated with the Generation of Procoagulant Platelets
Y Zhang, S Reitsma, O Babur, A Melrose, J Pang, S Hodapp, A Newton, ...
Research and Practice in Thrombosis and Haemostasis 7, 101670, 2023
2023
Protein Kinase C Theta (PKCθ) Signaling Associated With The Generation Of Procoagulant Platelets Revealed By Phosphoproteomics And Systems Analysis
Y Zheng, S Reitsma, O Babur, A Melrose, J Pang, S Hodapp, A Newton, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 43 (Suppl_1), A123-A123, 2023
2023
Effect Of Antiplatelet Agents And Tyrosine Kinase Inhibitors On OxLDL-mediated Platelet Procoagulant Activity
TJ Zheng, J Pang, T Kohs, S Reitsma, I Parra-Izquierdo, A Melrose, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 42 (Suppl_1), A159-A159, 2022
2022
Quantitative Phosphoproteomics And Causal Analysis Reveal Distinct And Combinatorial Signaling Mechanisms In Protease-Activated Receptor PAR1 And PAR4 Platelet Activation Programs
S Reitsma, J Klimek, I Parra-Izquierdo, O Babur, A Melrose, T Zheng, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 41 (Suppl_1), A108-A108, 2021
2021
Phosphoproteomic Profiling and Causal Pathway Mapping Reveal Signaling Relations in GPVI/ITAM-mediated Platelet Activation Programs
O Babur, A Melrose, OJ McCarty, P Wilmarth, J Aslan
Arteriosclerosis, Thrombosis, and Vascular Biology 40 (Suppl_1), A137-A137, 2020
2020
Quantitative Phosphoproteomic Profiling and Causality Pathway Mapping the Platelet Response to Vascular Injury
Ö Babur, A Melrose, J Cunliffe, AL Sepp, AT Ngo, O McCarty, J Klimek, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 39 (Suppl_1), A156-A156, 2019
2019
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