| FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity K Gopal, R Al Batran, TR Altamimi, AA Greenwell, CT Saed, SAT Dakhili, ... Cell Reports 35 (1), 2021 | 31 | 2021 |
| Pyruvate dehydrogenase as a therapeutic target for nonalcoholic fatty liver disease CT Saed, SA Tabatabaei Dakhili, JR Ussher ACS Pharmacology & Translational Science 4 (2), 582-588, 2021 | 16 | 2021 |
| Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation AA Greenwell, K Gopal, TR Altamimi, CT Saed, F Wang, ... American Journal of Physiology-Heart and Circulatory Physiology 320 (6 …, 2021 | 12 | 2021 |
| Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation K Gopal, QG Karwi, SA Tabatabaei Dakhili, CS Wagg, L Zhang, Q Sun, ... Cardiovascular Diabetology 22 (1), 73, 2023 | 10 | 2023 |
| Ketone ester administration improves glycemia in obese mice SA Tabatabaei Dakhili, K Yang, CAA Locatelli, CT Saed, AA Greenwell, ... American Journal of Physiology-Cell Physiology 325 (3), C750-C757, 2023 | 5 | 2023 |
| The antipsychotic dopamine 2 receptor antagonist diphenylbutylpiperidines improve glycemia in experimental obesity by inhibiting succinyl-CoA: 3-ketoacid CoA transferase SA Tabatabaei Dakhili, AA Greenwell, K Yang, R Abou Farraj, CT Saed, ... Diabetes 72 (1), 126-134, 2023 | 4 | 2023 |
| An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice AA Greenwell, CT Saed, SAT Dakhili, KL Ho, K Gopal, JSF Chan, ... American Journal of Physiology-Endocrinology and Metabolism, 2022 | 4 | 2022 |
| Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis K Gopal, AM Abdualkader, X Li, AA Greenwell, QG Karwi, TR Altamimi, ... Journal of Biological Chemistry 299 (12), 2023 | 2 | 2023 |
| 207-LB: aldose reductase inhibition by AT-001 limits diastolic dysfunction and adverse remodelling in diabetic cardiomyopathy QG KARWI, K GOPAL, S AMIRHOSSEIN TABATABAEI DAKHILI, ... Diabetes 71 (Supplement_1), 2022 | 1 | 2022 |
| The anti-anginal ranolazine does not confer beneficial actions against hepatic steatosis in male mice subjected to high-fat diet and streptozotocin-induced type 2 diabetes CT Saed, AA Greenwell, SA Tabatabaei Dakhili, K Gopal, F Eaton, ... Canadian Journal of Physiology and Pharmacology 100 (5), 393-401, 2022 | 1 | 2022 |
| Inhibition of pyruvate dehydrogenase kinase does not improve cardiac abnormalities in a mouse model of human Barth syndrome AA Greenwell, CT Saed, K Gopal, SA Tabatabaei Dakhili, J Kruger, ... Circulation 144 (Suppl_1), A11800-A11800, 2021 | 1 | 2021 |
| Pharmacological Inhibition of Succinyl Coenzyme A: 3‐Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy AA Greenwell, SA Tabatabaei Dakhili, CS Wagg, CT Saed, JSF Chan, ... Journal of the American Heart Association, e032697, 2024 | | 2024 |
| SEX-SPECIFIC DIFFERENCES IN CARDIAC ENERGY METABOLISM REGULATIONS IN AN EXPERIMENTAL TYPE 2 DIABETES MOUSE MODEL K Gopal, C Saed, J Chan, R Kirschenman, T Dimaano, F Benyaminov, ... Canadian Journal of Diabetes 47 (7), S4-S5, 2023 | | 2023 |
| The antianginal ranolazine fails to improve glycaemia in obese liver‐specific pyruvate dehydrogenase deficient male mice CT Saed, SA Tabatabaei Dakhili, AA Greenwell, JSF Chan, K Yang, ... Basic & Clinical Pharmacology & Toxicology 133 (2), 194-201, 2023 | | 2023 |
| Loss of Skeletal Muscle Pyruvate Dehydrogenase Induces Lactic Acidosis and Adaptive Anaplerotic Compensation via Pyruvate-Alanine Cycling and Glutaminolysis K Gopal, AM Abdualkader, X Li, AA Greenwell, QG Karwi, C Saed, ... bioRxiv, 2023.05. 10.540277, 2023 | | 2023 |
| Elucidating the sex differences in a translational mouse model of diabetic cardiomyopathy K Gopal, C Saed, J Chan, T Dimaano, F Benyaminov, A Greenwell, ... Journal of Molecular and Cellular Cardiology 173, S119-S120, 2022 | | 2022 |
| Aldose Reductase Inhibition by AT-001 Alleviates Fibrosis and Adverse Remodelling in Diabetic Cardiomyopathy by Reducing Myocardial Fatty Acid Oxidation K Gopal, Q Karwi, SAT Dakhili, CS Wagg, L Zhang, Q Sun, C Saed, ... CIRCULATION RESEARCH 131 (12), E170-E170, 2022 | | 2022 |
| Stimulating myocardial pyruvate dehydrogenase activity fails to alleviate cardiac abnormalities in a mouse model of human Barth syndrome AA Greenwell, SA Tabatabaei Dakhili, K Gopal, CT Saed, JSF Chan, ... Frontiers in Cardiovascular Medicine 9, 997352, 2022 | | 2022 |
| The Antipsychotic D2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA-3-Ketoacid CoA transferase SAT Dakhili, R Abou Farraj, AA Greenwell, CT Saed, K Yang, K Gopal, ... DIABETES 71, 2022 | | 2022 |
| 233-LB: Ranolazine Fails to Improve Glycemia in Obese Liver-Specific Pyruvate Dehydrogenase–Deficient Mice CT Saed, S AMIRHOSSEIN TABATABAEI DAKHILI, AA Greenwell, ... Diabetes 71 (Supplement_1), 2022 | | 2022 |
