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dorothy colagiovanni
dorothy colagiovanni
Senior Director of Toxicology, N30 Pharma
Verified email at n30pharma.com
Title
Cited by
Cited by
Year
Disparate roles for TNF-α and Fas ligand in concanavalin A-induced hepatitis
R Ksontini, DB Colagiovanni, MD Josephs, CK Edwards, CL Tannahill, ...
The Journal of Immunology 160 (8), 4082-4089, 1998
2091998
Synergistic action of the benzene metabolite hydroquinone on myelopoietic stimulating activity of granulocyte/macrophage colony-stimulating factor in vitro.
RD Irons, WS Stillman, DB Colagiovanni, VA Henry
Proceedings of the National Academy of Sciences 89 (9), 3691-3695, 1992
841992
Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson’s disease
BR De Miranda, JA Miller, RJ Hansen, PJ Lunghofer, S Safe, ...
Journal of Pharmacology and Experimental Therapeutics 345 (1), 125-138, 2013
692013
S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury
AG Cox, DC Saunders, PB Kelsey, AA Conway, Y Tesmenitsky, ...
Cell reports 6 (1), 56-69, 2014
592014
Discovery of S-Nitrosoglutathione Reductase Inhibitors: Potential Agents for the Treatment of Asthma and Other Inflammatory Diseases
X Sun, JWF Wasley, J Qiu, JP Blonder, AM Stout, LS Green, SA Strong, ...
ACS medicinal chemistry letters 2 (5), 402-406, 2011
572011
Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities
X Sun, J Qiu, SA Strong, LS Green, JWF Wasley, JP Blonder, ...
Bioorganic & medicinal chemistry letters 21 (19), 5849-5853, 2011
392011
A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma
DB Colagiovanni, DW Drolet, E Langlois-Forget, MP Piché, D Looker, ...
Regulatory Toxicology and Pharmacology 62 (1), 115-124, 2012
362012
Pharmacokinetics, safety, and efficacy of a liposome encapsulated thymidylate synthase inhibitor, OSI-7904L [(S)-2-[5-[(1, 2-dihydro-3-methyl-1-oxobenzo [f] quinazolin-9-yl …
J Desjardins, DL Emerson, DB Colagiovanni, E Abbott, EN Brown, ...
Journal of Pharmacology and Experimental Therapeutics 309 (3), 894-902, 2004
252004
Structure–activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: pyrrole regioisomers and propionic acid replacement
X Sun, J Qiu, SA Strong, LS Green, JWF Wasley, DB Colagiovanni, ...
Bioorganic & medicinal chemistry letters 21 (12), 3671-3675, 2011
242011
Structure–activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: Carboxamide modification
X Sun, J Qiu, SA Strong, LS Green, JWF Wasley, JP Blonder, ...
Bioorganic & medicinal chemistry letters 22 (6), 2338-2342, 2012
192012
Chemical suppression of a subpopulation of primitive hematopoietic progenitor cells: 1, 3-butadiene produces a hematopoietic defect similar to steel or white spotted mutations …
DB Colagiovanni, WS Stillman, RD Irons
Proceedings of the National Academy of Sciences 90 (7), 2803-2806, 1993
141993
Preclinical 28-Day Inhalation Toxicity Assessment of S-Nitrosoglutathione in Beagle Dogs and Wistar Rats
DB Colagiovanni, D Borkhataria, D Looker, D Schuler, C Bachmann, ...
International Journal of Toxicology 30 (5), 466-477, 2011
132011
Murine thymic lymphoma is associated with a species-specific hematopoietic progenitor cell subpopulation
RD Irons, DB Colagiovanni, WS Stillman
Toxicology 113 (1-3), 59-67, 1996
131996
Effect of MPC-11 myeloma and MPC-11+ IL-1 receptor antagonist treatment on mouse bone properties
VL Ferguson, SJ Simske, RA Ayers, TA Bateman, HT Wang, A Bendele, ...
Bone 30 (1), 109-116, 2002
122002
SAR studies on dihydropyrimidinone antibiotics
L Xu, L Zhang, R Jones, C Bryant, N Boddeker, E Mabery, G Bahador, ...
Bioorganic & medicinal chemistry letters 21 (6), 1670-1674, 2011
92011
Juvenile toxicity study of faropenem medoxomil in beagle puppies
AS Faqi, C Lanphear, S Gill, DB Colagiovanni
Reproductive Toxicology 30 (4), 619-624, 2010
82010
Safety Assessment of 4′-Thio-β-d-Arabinofuranosylcytosine in the Beagle Dog Suggests a Drug-Induced Centrally Mediated Effect on the Hypothalamic-Pituitary …
DB Colagiovanni, DW Drolet, L Dihel, DJ Meyer, K Hart, J Wolf
International journal of toxicology 25 (2), 119-126, 2006
82006
Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents for Liver Toxicity
GJ Rosenthal, CH Scoggin, D Colagiovanni
US Patent App. 14/126,468, 2014
72014
High γ-glutamyltransferase (GGT) activity in human breast milk confounds interpretation of high serum GGT activity in a nursing infant with liver disease
DB Colagiovanni, DJ Meyer, JM Wolf, K Hart, E Abbott, C Santos
Clinical chemistry 51 (9), 1750-1751, 2005
72005
Comparative efficacy of sTNFR-I, a novel monomeric recombinant soluble TNF type I receptor to dimeric sTNFR-I and sTNFR-II IgG Fc fusion proteins in animal models of rheumatoid …
AM Bendele, J McComb, T Gould, L Chilipala, J Frazier, D Colagiovanni, ...
J Interferon Cytokine Res 18, 89A, 1998
71998
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