Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma RE Davis, VN Ngo, G Lenz, P Tolar, RM Young, PB Romesser, ... Nature 463 (7277), 88-92, 2010 | 1911 | 2010 |
Genetics and pathogenesis of diffuse large B-cell lymphoma R Schmitz, GW Wright, DW Huang, CA Johnson, JD Phelan, JQ Wang, ... New England journal of medicine 378 (15), 1396-1407, 2018 | 1866 | 2018 |
Oncogenically active MYD88 mutations in human lymphoma VN Ngo, RM Young, R Schmitz, S Jhavar, W Xiao, KH Lim, ... Nature 470 (7332), 115-119, 2011 | 1757 | 2011 |
Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma WH Wilson, RM Young, R Schmitz, Y Yang, S Pittaluga, G Wright, CJ Lih, ... Nature medicine 21 (8), 922-926, 2015 | 1205 | 2015 |
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics R Schmitz, RM Young, M Ceribelli, S Jhavar, W Xiao, M Zhang, G Wright, ... Nature 490 (7418), 116-120, 2012 | 984 | 2012 |
A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications GW Wright, JD Phelan, ZA Coulibaly, S Roulland, RM Young, JQ Wang, ... Cancer cell 37 (4), 551-568. e14, 2020 | 814 | 2020 |
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma Y Yang, AL Shaffer, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ... Cancer cell 21 (6), 723-737, 2012 | 602 | 2012 |
Pathogenesis of human B cell lymphomas AL Shaffer III, RM Young, LM Staudt Annual review of immunology 30 (1), 565-610, 2012 | 540 | 2012 |
Targeting pathological B cell receptor signalling in lymphoid malignancies RM Young, LM Staudt Nature reviews Drug discovery 12 (3), 229-243, 2013 | 486 | 2013 |
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells LA Mathews Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, ... Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014 | 414 | 2014 |
A multiprotein supercomplex controlling oncogenic signalling in lymphoma JD Phelan, RM Young, DE Webster, S Roulland, GW Wright, M Kasbekar, ... Nature 560 (7718), 387-391, 2018 | 360 | 2018 |
B-cell receptor signaling in diffuse large B-cell lymphoma RM Young, AL Shaffer III, JD Phelan, LM Staudt Seminars in hematology 52 (2), 77-85, 2015 | 240 | 2015 |
A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylation RM Young, D Holowka, B Baird Journal of Biological Chemistry 278 (23), 20746-20752, 2003 | 205 | 2003 |
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens RM Young, T Wu, R Schmitz, M Dawood, W Xiao, JD Phelan, W Xu, ... Proceedings of the National Academy of Sciences 112 (44), 13447-13454, 2015 | 190 | 2015 |
Lipid segregation and IgE receptor signaling: a decade of progress D Holowka, JA Gosse, AT Hammond, X Han, P Sengupta, NL Smith, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1746 (3), 252-259, 2005 | 175 | 2005 |
Function and regulation of SPLUNC1 protein in Mycoplasma infection and allergic inflammation HW Chu, J Thaikoottathil, JG Rino, G Zhang, Q Wu, T Moss, Y Refaeli, ... The Journal of Immunology 179 (6), 3995-4002, 2007 | 169 | 2007 |
Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target RM Young, IR Hardy, RL Clarke, N Lundy, P Pine, BC Turner, TA Potter, ... Blood, The Journal of the American Society of Hematology 113 (11), 2508-2516, 2009 | 143 | 2009 |
The B Cell Antigen Receptor and Overexpression of MYC Can Cooperate in the Genesis of B Cell Lymphomas Y Refaeli, RM Young, BC Turner, J Duda, KA Field, JM Bishop PLoS biology 6 (6), e152, 2008 | 130 | 2008 |
Pathogenic B‐cell receptor signaling in lymphoid malignancies: new insights to improve treatment RM Young, JD Phelan, WH Wilson, LM Staudt Immunological reviews 291 (1), 190-213, 2019 | 123 | 2019 |
Targeting non-proteolytic protein ubiquitination for the treatment of diffuse large B cell lymphoma Y Yang, P Kelly, AL Shaffer, R Schmitz, HM Yoo, X Liu, D Webster, ... Cancer cell 29 (4), 494-507, 2016 | 101 | 2016 |