| Genome-scale CRISPR-Cas9 knockout screening in human cells O Shalem, NE Sanjana, E Hartenian, X Shi, DA Scott, TS Mikkelsen, ... Science 343 (6166), 84-87, 2014 | 5833 | 2014 |
| DNA targeting specificity of RNA-guided Cas9 nucleases PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, ... Nature biotechnology 31 (9), 827-832, 2013 | 5637 | 2013 |
| Improved vectors and genome-wide libraries for CRISPR screening NE Sanjana, O Shalem, F Zhang Nature methods 11 (8), 783-784, 2014 | 5237 | 2014 |
| In vivo genome editing using Staphylococcus aureus Cas9 FA Ran, L Cong, WX Yan, DA Scott, JS Gootenberg, AJ Kriz, B Zetsche, ... Nature 520 (7546), 186-191, 2015 | 3150 | 2015 |
| High-throughput functional genomics using CRISPR–Cas9 O Shalem, NE Sanjana, F Zhang Nature Reviews Genetics 16 (5), 299-311, 2015 | 1400 | 2015 |
| Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis S Chen, NE Sanjana, K Zheng, O Shalem, K Lee, X Shi, DA Scott, J Song, ... Cell 160 (6), 1246-1260, 2015 | 1105 | 2015 |
| BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015 | 966 | 2015 |
| A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks O Parnas, M Jovanovic, TM Eisenhaure, RH Herbst, A Dixit, CJ Ye, ... Cell 162 (3), 675-686, 2015 | 537 | 2015 |
| Hypoxia as a therapy for mitochondrial disease IH Jain, L Zazzeron, R Goli, K Alexa, S Schatzman-Bone, H Dhillon, ... Science 352 (6281), 54-61, 2016 | 444 | 2016 |
| Axonal transcription factors signal retrogradely in lesioned peripheral nerve K Ben‐Yaakov, SY Dagan, Y Segal‐Ruder, O Shalem, D Vuppalanchi, ... The EMBO journal 31 (6), 1350-1363, 2012 | 332 | 2012 |
| High-resolution interrogation of functional elements in the noncoding genome ZF Sanjana NE, Wright J, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng C ... Science 353 (6307), 1545-1549, 2016 | 328 | 2016 |
| Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation O Shalem, O Dahan, M Levo, MR Martinez, I Furman, E Segal, Y Pilpel Molecular systems biology 4 (1), 4, 2008 | 232 | 2008 |
| Signaling to transcription networks in the neuronal retrograde injury response I Michaelevski, Y Segal-Ruder, M Rozenbaum, KF Medzihradszky, ... Science signaling 3 (130), ra53-ra53, 2010 | 202 | 2010 |
| Transcriptome kinetics is governed by a genome-wide coupling of mRNA production and degradation: a role for RNA Pol II O Shalem, B Groisman, M Choder, O Dahan, Y Pilpel PLoS genetics 7 (9), e1002273, 2011 | 112 | 2011 |
| Systematic dissection of the sequence determinants of gene 3’end mediated expression control O Shalem, E Sharon, S Lubliner, I Regev, M Lotan-Pompan, Z Yakhini, ... PLoS genetics 11 (4), e1005147, 2015 | 74 | 2015 |
| Widespread promoter-mediated coordination of transcription and mRNA degradation M Dori-Bachash, O Shalem, YS Manor, Y Pilpel, I Tirosh Genome biology 13, 1-14, 2012 | 53 | 2012 |
| Measurements of the impact of 3′ end sequences on gene expression reveal wide range and sequence dependent effects O Shalem, L Carey, D Zeevi, E Sharon, L Keren, A Weinberger, O Dahan, ... PLoS computational biology 9 (3), e1002934, 2013 | 31 | 2013 |
