Beyond the margins: real-time detection of cancer using targeted fluorophores RR Zhang, AB Schroeder, JJ Grudzinski, EL Rosenthal, JM Warram, ... Nature reviews Clinical oncology 14 (6), 347-364, 2017 | 413 | 2017 |
Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy JP Weichert, PA Clark, IK Kandela, AM Vaccaro, W Clarke, MA Longino, ... Science translational medicine 6 (240), 240ra75-240ra75, 2014 | 131 | 2014 |
Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade RB Patel, R Hernandez, P Carlson, J Grudzinski, AM Bates, ... Science translational medicine 13 (602), eabb3631, 2021 | 109 | 2021 |
Synthesis and structure− activity relationship effects on the tumor avidity of radioiodinated phospholipid ether analogues AN Pinchuk, MA Rampy, MA Longino, RWS Skinner, MD Gross, ... Journal of medicinal chemistry 49 (7), 2155-2165, 2006 | 83 | 2006 |
Current status of radiopharmaceutical therapy SS James, B Bednarz, S Benedict, JC Buchsbaum, Y Dewaraja, E Frey, ... International Journal of Radiation Oncology* Biology* Physics 109 (4), 891-901, 2021 | 65 | 2021 |
Development and validation of RAPID: a patient-specific Monte Carlo three-dimensional internal dosimetry platform AE Besemer, YM Yang, JJ Grudzinski, LT Hall, BP Bednarz Cancer biotherapy & radiopharmaceuticals 33 (4), 155-165, 2018 | 60 | 2018 |
90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin’s Lymphoma R Hernandez, KL Walker, JJ Grudzinski, E Aluicio-Sarduy, R Patel, ... Communications biology 2 (1), 79, 2019 | 52 | 2019 |
Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy JC Jagodinsky, WJ Jin, AM Bates, R Hernandez, JJ Grudzinski, IR Marsh, ... Theranostics 11 (13), 6120, 2021 | 42 | 2021 |
Treatment planning system for radiopharmaceuticals JJ Grudzinski, R Jeraj, WA Tome, JP Weichert US Patent 10,007,961, 2018 | 31 | 2018 |
177Lu-NM600 targeted radionuclide therapy extends survival in syngeneic murine models of triple-negative breast cancer R Hernandez, JJ Grudzinski, E Aluicio-Sarduy, CF Massey, AN Pinchuk, ... Journal of Nuclear Medicine 61 (8), 1187-1194, 2020 | 30 | 2020 |
A Phase 1 Study of 131I-CLR1404 in Patients with Relapsed or Refractory Advanced Solid Tumors: Dosimetry, Biodistribution, Pharmacokinetics, and Safety JJ Grudzinski, B Titz, K Kozak, W Clarke, E Allen, LA Trembath, M Stabin, ... PloS one 9 (11), e111652, 2014 | 30 | 2014 |
Preclinical characterization of 86/90Y-NM600 in a variety of murine and human cancer tumor models JJ Grudzinski, R Hernandez, I Marsh, RB Patel, E Aluicio-Sarduy, J Engle, ... Journal of Nuclear Medicine 60 (11), 1622-1628, 2019 | 25 | 2019 |
Preclinical pharmacokinetics and dosimetry studies of 124I/131I-CLR1404 for treatment of pediatric solid tumors in murine xenograft models IR Marsh, J Grudzinski, DC Baiu, A Besemer, R Hernandez, JJ Jeffery, ... Journal of Nuclear Medicine 60 (10), 1414-1420, 2019 | 25 | 2019 |
Phospholipid ether analogs for the detection of colorectal tumors DA Deming, ME Maher, AA Leystra, JP Grudzinski, L Clipson, ... PloS one 9 (10), e109668, 2014 | 24 | 2014 |
CLR 125 Auger electrons for the targeted radiotherapy of triple-negative breast cancer J Grudzinski, I Marsh, B Titz, J Jeffery, M Longino, K Kozak, K Lange, ... Cancer Biotherapy & Radiopharmaceuticals 33 (3), 87-95, 2018 | 18 | 2018 |
Murine-specific internal dosimetry for preclinical investigations of imaging and therapeutic agents B Bednarz, J Grudzinski, I Marsh, A Besemer, D Baiu, J Weichert, M Otto Health physics 114 (4), 450-459, 2018 | 18 | 2018 |
Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative … K Magee, IR Marsh, MM Turek, J Grudzinski, E Aluicio-Sarduy, JW Engle, ... PLoS One 16 (8), e0255798, 2021 | 17 | 2021 |
Phospholipid ether analogs as cancer-targeting drug vehicles JP Weichert, A Pinchuk, K Kozak, M Longino, J Grudzinski, B Titz, C Pak, ... US Patent 9,345,718, 2016 | 17 | 2016 |
Impact of PET and MRI threshold-based tumor volume segmentation on patient-specific targeted radionuclide therapy dosimetry using CLR1404 AE Besemer, B Titz, JJ Grudzinski, JP Weichert, JS Kuo, HI Robins, ... Physics in Medicine & Biology 62 (15), 6008, 2017 | 16 | 2017 |
The biological effectiveness of targeted radionuclide therapy based on a whole-body pharmacokinetic model JJ Grudzinski, W Tomé, JP Weichert, R Jeraj Physics in Medicine & Biology 55 (19), 5723, 2010 | 15 | 2010 |