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Joseph Grudzinski
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Beyond the margins: real-time detection of cancer using targeted fluorophores
RR Zhang, AB Schroeder, JJ Grudzinski, EL Rosenthal, JM Warram, ...
Nature reviews Clinical oncology 14 (6), 347-364, 2017
4132017
Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy
JP Weichert, PA Clark, IK Kandela, AM Vaccaro, W Clarke, MA Longino, ...
Science translational medicine 6 (240), 240ra75-240ra75, 2014
1312014
Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade
RB Patel, R Hernandez, P Carlson, J Grudzinski, AM Bates, ...
Science translational medicine 13 (602), eabb3631, 2021
1092021
Synthesis and structure− activity relationship effects on the tumor avidity of radioiodinated phospholipid ether analogues
AN Pinchuk, MA Rampy, MA Longino, RWS Skinner, MD Gross, ...
Journal of medicinal chemistry 49 (7), 2155-2165, 2006
832006
Current status of radiopharmaceutical therapy
SS James, B Bednarz, S Benedict, JC Buchsbaum, Y Dewaraja, E Frey, ...
International Journal of Radiation Oncology* Biology* Physics 109 (4), 891-901, 2021
652021
Development and validation of RAPID: a patient-specific Monte Carlo three-dimensional internal dosimetry platform
AE Besemer, YM Yang, JJ Grudzinski, LT Hall, BP Bednarz
Cancer biotherapy & radiopharmaceuticals 33 (4), 155-165, 2018
602018
90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin’s Lymphoma
R Hernandez, KL Walker, JJ Grudzinski, E Aluicio-Sarduy, R Patel, ...
Communications biology 2 (1), 79, 2019
522019
Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy
JC Jagodinsky, WJ Jin, AM Bates, R Hernandez, JJ Grudzinski, IR Marsh, ...
Theranostics 11 (13), 6120, 2021
422021
Treatment planning system for radiopharmaceuticals
JJ Grudzinski, R Jeraj, WA Tome, JP Weichert
US Patent 10,007,961, 2018
312018
177Lu-NM600 targeted radionuclide therapy extends survival in syngeneic murine models of triple-negative breast cancer
R Hernandez, JJ Grudzinski, E Aluicio-Sarduy, CF Massey, AN Pinchuk, ...
Journal of Nuclear Medicine 61 (8), 1187-1194, 2020
302020
A Phase 1 Study of 131I-CLR1404 in Patients with Relapsed or Refractory Advanced Solid Tumors: Dosimetry, Biodistribution, Pharmacokinetics, and Safety
JJ Grudzinski, B Titz, K Kozak, W Clarke, E Allen, LA Trembath, M Stabin, ...
PloS one 9 (11), e111652, 2014
302014
Preclinical characterization of 86/90Y-NM600 in a variety of murine and human cancer tumor models
JJ Grudzinski, R Hernandez, I Marsh, RB Patel, E Aluicio-Sarduy, J Engle, ...
Journal of Nuclear Medicine 60 (11), 1622-1628, 2019
252019
Preclinical pharmacokinetics and dosimetry studies of 124I/131I-CLR1404 for treatment of pediatric solid tumors in murine xenograft models
IR Marsh, J Grudzinski, DC Baiu, A Besemer, R Hernandez, JJ Jeffery, ...
Journal of Nuclear Medicine 60 (10), 1414-1420, 2019
252019
Phospholipid ether analogs for the detection of colorectal tumors
DA Deming, ME Maher, AA Leystra, JP Grudzinski, L Clipson, ...
PloS one 9 (10), e109668, 2014
242014
CLR 125 Auger electrons for the targeted radiotherapy of triple-negative breast cancer
J Grudzinski, I Marsh, B Titz, J Jeffery, M Longino, K Kozak, K Lange, ...
Cancer Biotherapy & Radiopharmaceuticals 33 (3), 87-95, 2018
182018
Murine-specific internal dosimetry for preclinical investigations of imaging and therapeutic agents
B Bednarz, J Grudzinski, I Marsh, A Besemer, D Baiu, J Weichert, M Otto
Health physics 114 (4), 450-459, 2018
182018
Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative …
K Magee, IR Marsh, MM Turek, J Grudzinski, E Aluicio-Sarduy, JW Engle, ...
PLoS One 16 (8), e0255798, 2021
172021
Phospholipid ether analogs as cancer-targeting drug vehicles
JP Weichert, A Pinchuk, K Kozak, M Longino, J Grudzinski, B Titz, C Pak, ...
US Patent 9,345,718, 2016
172016
Impact of PET and MRI threshold-based tumor volume segmentation on patient-specific targeted radionuclide therapy dosimetry using CLR1404
AE Besemer, B Titz, JJ Grudzinski, JP Weichert, JS Kuo, HI Robins, ...
Physics in Medicine & Biology 62 (15), 6008, 2017
162017
The biological effectiveness of targeted radionuclide therapy based on a whole-body pharmacokinetic model
JJ Grudzinski, W Tomé, JP Weichert, R Jeraj
Physics in Medicine & Biology 55 (19), 5723, 2010
152010
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Articles 1–20