| GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a β-arrestin 1-mediated ERK1/2 activation in pancreatic β-cells J Quoyer, C Longuet, C Broca, N Linck, S Costes, E Varin, J Bockaert, ... Journal of Biological Chemistry 285 (3), 1989-2002, 2010 | 203 | 2010 |
| Circulating levels of soluble dipeptidyl peptidase-4 are dissociated from inflammation and induced by enzymatic DPP4 inhibition EM Varin, EE Mulvihill, JL Beaudry, G Pujadas, S Fuchs, JF Tanti, S Fazio, ... Cell metabolism 29 (2), 320-334. e5, 2019 | 114 | 2019 |
| Cellular sites and mechanisms linking reduction of dipeptidyl peptidase-4 activity to control of incretin hormone action and glucose homeostasis EE Mulvihill, EM Varin, B Gladanac, JE Campbell, JR Ussher, LL Baggio, ... Cell metabolism 25 (1), 152-165, 2017 | 100 | 2017 |
| Inhibition of dipeptidyl peptidase-4 impairs ventricular function and promotes cardiac fibrosis in high fat–fed diabetic mice EE Mulvihill, EM Varin, JR Ussher, JE Campbell, KWA Bang, T Abdullah, ... Diabetes 65 (3), 742-754, 2016 | 84 | 2016 |
| Roles and regulation of the transcription factor CREB in pancreatic β-cells S Dalle, J Quoyer, E Varin, S Costes Current molecular pharmacology 4 (3), 187-195, 2011 | 82 | 2011 |
| Distinct neural sites of GLP-1R expression mediate physiological versus pharmacological control of incretin action EM Varin, EE Mulvihill, LL Baggio, JA Koehler, X Cao, RJ Seeley, ... Cell reports 27 (11), 3371-3384. e3, 2019 | 74 | 2019 |
| The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice JL Beaudry, KD Kaur, EM Varin, LL Baggio, X Cao, EE Mulvihill, JH Stern, ... Molecular metabolism 22, 37-48, 2019 | 69 | 2019 |
| Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets C Broca, E Varin, M Armanet, C Tourrel-Cuzin, D Bosco, S Dalle, ... PloS one 9 (3), e92066, 2014 | 56 | 2014 |
| Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans LL Baggio, EM Varin, JA Koehler, X Cao, Y Lokhnygina, SR Stevens, ... Nature communications 11 (1), 3766, 2020 | 51 | 2020 |
| Physiological roles of the GIP receptor in murine brown adipose tissue JL Beaudry, KD Kaur, EM Varin, LL Baggio, X Cao, EE Mulvihill, HE Bates, ... Molecular metabolism 28, 14-25, 2019 | 41 | 2019 |
| Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4 EM Varin, A Wojtusciszyn, C Broca, D Muller, MA Ravier, F Ceppo, ... Cell death & disease 7 (1), e2065-e2065, 2016 | 25 | 2016 |
| Glucagon-like peptide-1 receptor agonists in adult patients with type 2 diabetes: review of cardiovascular outcome trials EM Varin, BA McLean, JA Lovshin Canadian Journal of Diabetes 44 (1), 68-77, 2020 | 18 | 2020 |
| Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice BL Panaro, AL Coppage, JL Beaudry, EM Varin, K Kaur, JH Lai, W Wu, ... Molecular Metabolism 19, 65-74, 2019 | 18 | 2019 |
| Loss of Glp2r signaling activates hepatic stellate cells and exacerbates diet-induced steatohepatitis in mice S Fuchs, B Yusta, LL Baggio, EM Varin, D Matthews, DJ Drucker JCI insight 5 (8), 2020 | 16 | 2020 |
| The gut hormone receptor GIPR links energy availability to the control of hematopoiesis G Pujadas, EM Varin, LL Baggio, EE Mulvihill, KWA Bang, JA Koehler, ... Molecular Metabolism 39, 101008, 2020 | 14 | 2020 |
| TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL S Dalle, JF Tanti, A Wojtusciszyn, E Varin | 12 | 2014 |
| Hematopoietic cell–versus enterocyte-derived dipeptidyl peptidase-4 differentially regulates triglyceride excursion in mice EM Varin, AA Hanson, JL Beaudry, MA Nguyen, X Cao, LL Baggio, ... JCI insight 5 (16), 2020 | 11 | 2020 |
| Correction: proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets C Broca, E Varin, M Armanet, C Tourrel-Cuzin, D Bosco, S Dalle, ... PLoS One 9 (7), e102652, 2014 | 3 | 2014 |
| Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress E Fadzeyeva, CAA Locatelli, NA Trzaskalski, MA Nguyen, ME Capozzi, ... Iscience 26 (5), 106748, 2023 | | 2023 |
| SAT-LB101 Loss of GLP-2R Signaling Activates Hepatic Stellate Cells and Exacerbates Diet-Induced Steatohepatitis in Mice SZ Fuchs, B Yusta, L Baggio, E Varin, D Matthews, DJ Drucker Journal of the Endocrine Society 4 (Supplement_1), SAT-LB101, 2020 | | 2020 |
Daniel J. DruckerLunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of TorontoVerified email at lunenfeld.ca
