Mark A. Lemmon, Ph.D., F.R.S.
Mark A. Lemmon, Ph.D., F.R.S.
David A. Sackler Professor of Pharmacology, Co-Director, Cancer Biology Institute, Yale University
Verified email at yale.edu - Homepage
Title
Cited by
Cited by
Year
Cell signaling by receptor tyrosine kinases
MA Lemmon, J Schlessinger
Cell 141 (7), 1117-1134, 2010
42882010
Membrane recognition by phospholipid-binding domains
MA Lemmon
Nature reviews Molecular cell biology 9 (2), 99-111, 2008
15522008
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
AW Burgess, HS Cho, C Eigenbrot, KM Ferguson, TPJ Garrett, DJ Leahy, ...
Molecular cell 12 (3), 541-552, 2003
11602003
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
MA LEMMON, KM FERGUSON
Biochemical Journal 350 (1), 1-18, 2000
9562000
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
KM Ferguson, MB Berger, JM Mendrola, HS Cho, DJ Leahy, MA Lemmon
Molecular cell 11 (2), 507-517, 2003
8952003
Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation
T Spivak-Kroizman, MA Lemmon, I Dikic, JE Ladbury, D Pinchasi, ...
Cell 79 (6), 1015-1024, 1994
8371994
Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain
KM Ferguson, MA Lemmon, J Schlessinger, PB Sigler
Cell 83 (6), 1037-1046, 1995
7341995
Phosphoinositide recognition domains
MA Lemmon
Traffic 4 (4), 201-213, 2003
7322003
Activation of phospholipase Cγ by PI 3‐kinase‐induced PH domain‐mediated membrane targeting
M Falasca, SK Logan, VP Lehto, G Baccante, MA Lemmon, ...
The EMBO journal 17 (2), 414-422, 1998
7041998
Regulation of signal transduction and signal diversity by receptor oligomerization
MA Lemmon, J Schlessinger
Trends in biochemical sciences 19 (11), 459-463, 1994
6891994
Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain
MA Lemmon, KM Ferguson, R O'Brien, PB Sigler, J Schlessinger
Proceedings of the National Academy of Sciences 92 (23), 10472-10476, 1995
6731995
Sequence specificity in the dimerization of transmembrane. alpha.-helixes
MA Lemmon, JM Flanagan, HR Treutlein, J Zhang, DM Engelman
Biochemistry 31 (51), 12719-12725, 1992
6351992
Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors?
J Schlessinger, I Lax, M Lemmon
Cell 83 (3), 357-360, 1995
6131995
PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface
MA Lemmon, KM Ferguson, J Schlessinger
Cell 85 (5), 621-624, 1996
5951996
Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices.
MA Lemmon, JM Flanagan, JF Hunt, BD Adair, BJ Bormann, CE Dempsey, ...
Journal of Biological Chemistry 267 (11), 7683-7689, 1992
5781992
Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains
JM Kavran, DE Klein, A Lee, M Falasca, SJ Isakoff, EY Skolnik, ...
Journal of Biological Chemistry 273 (46), 30497-30508, 1998
5381998
ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation
F Shi, SE Telesco, Y Liu, R Radhakrishnan, MA Lemmon
Proceedings of the National Academy of Sciences 107 (17), 7692-7697, 2010
4662010
Two EGF molecules contribute additively to stabilization of the EGFR dimer
MA Lemmon, Z Bu, JE Ladbury, M Zhou, D Pinchasi, I Lax, DM Engelman, ...
The EMBO journal 16 (2), 281-294, 1997
4651997
SH2 and PTB domains in tyrosine kinase signaling
J Schlessinger, MA Lemmon
Science's STKE 2003 (191), re12-re12, 2003
4362003
Identification and analysis of PH domain‐containing targets of phosphatidylinositol 3‐kinase using a novel in vivo assay in yeast
SJ Isakoff, T Cardozo, J Andreev, Z Li, KM Ferguson, R Abagyan, ...
The EMBO journal 17 (18), 5374-5387, 1998
4081998
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