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Leah Siskind
Leah Siskind
Verified email at louisville.edu - Homepage
Title
Cited by
Cited by
Year
Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis
JE Chipuk, GP McStay, A Bharti, T Kuwana, CJ Clarke, LJ Siskind, ...
Cell 148 (5), 988-1000, 2012
4882012
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins
LJ Siskind, RN Kolesnick, M Colombini
Journal of Biological Chemistry 277 (30), 26796-26803, 2002
4712002
The lipids C2-and C16-ceramide form large stable channels: implications for apoptosis
LJ Siskind, M Colombini
Journal of Biological Chemistry 275 (49), 38640-38644, 2000
3782000
Mitochondrial ceramide and the induction of apoptosis
LJ Siskind
Journal of bioenergetics and biomembranes 37, 143-153, 2005
3212005
Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations
LJ Siskind, RN Kolesnick, M Colombini
Mitochondrion 6 (3), 118-125, 2006
2842006
Ceramide starves cells to death by downregulating nutrient transporter proteins
GG Guenther, ER Peralta, KR Rosales, SY Wong, LJ Siskind, AL Edinger
Proceedings of the National Academy of Sciences 105 (45), 17402-17407, 2008
2332008
The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis
LJ Siskind, TD Mullen, KR Rosales, CJ Clarke, MJ Hernandez-Corbacho, ...
Journal of Biological Chemistry 285 (16), 11818-11826, 2010
1592010
Anti-apoptotic Bcl-2 family proteins disassemble ceramide channels
LJ Siskind, L Feinstein, T Yu, JS Davis, D Jones, J Choi, JE Zuckerman, ...
Journal of Biological Chemistry 283 (11), 6622-6630, 2008
1522008
Sphingolipids and mitochondrial apoptosis
GA Patwardhan, LJ Beverly, LJ Siskind
Journal of bioenergetics and biomembranes 48, 153-168, 2016
1462016
Repeated administration of low-dose cisplatin in mice induces fibrosis
CN Sharp, MA Doll, TV Dupre, PP Shah, M Subathra, D Siow, GE Arteel, ...
American Journal of Physiology-Renal Physiology 310 (6), F560-F568, 2016
1292016
Developing better mouse models to study cisplatin-induced kidney injury
CN Sharp, LJ Siskind
American Journal of Physiology-Renal Physiology 313 (4), F835-F841, 2017
1182017
Enlargement and contracture of C2-ceramide channels
LJ Siskind, A Davoody, N Lewin, S Marshall, M Colombini
Biophysical journal 85 (3), 1560-1575, 2003
1132003
Sphingosine forms channels in membranes that differ greatly from those formed by ceramide
LJ Siskind, S Fluss, M Bui, M Colombini
Journal of bioenergetics and biomembranes 37, 227-236, 2005
922005
Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis
C Ding, R Shrestha, X Zhu, AE Geller, S Wu, MR Woeste, W Li, H Wang, ...
Nature immunology 24 (2), 239-254, 2023
902023
Subclinical kidney injury induced by repeated cisplatin administration results in progressive chronic kidney disease
CN Sharp, MA Doll, J Megyesi, GB Oropilla, LJ Beverly, LJ Siskind
American Journal of Physiology-Renal Physiology 315 (1), F161-F172, 2018
832018
Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis
TK Nowling, AR Mather, T Thiyagarajan, MJ Hernández-Corbacho, ...
Journal of the American Society of Nephrology 26 (6), 1402-1413, 2015
802015
Experimental models of acute kidney injury for translational research
NA Hukriede, DE Soranno, V Sander, T Perreau, MC Starr, PST Yuen, ...
Nature Reviews Nephrology 18 (5), 277-293, 2022
762022
Potential therapeutic targets for cisplatin-induced kidney injury: lessons from other models of AKI and fibrosis
SM Sears, LJ Siskind
Journal of the American Society of Nephrology 32 (7), 1559-1567, 2021
752021
Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells
M Subathra, M Korrapati, LA Howell, JM Arthur, JA Shayman, ...
American Journal of Physiology-Renal Physiology 309 (3), F204-F215, 2015
722015
Common cytotoxic chemotherapeutics induce epithelial-mesenchymal transition (EMT) downstream of ER stress
PP Shah, TV Dupre, LJ Siskind, LJ Beverly
Oncotarget 8 (14), 22625, 2017
682017
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