|Isoform-selective inhibition of phosphoinositide 3-kinase: identification of a new region of nonconserved amino acids critical for p110α inhibition|
Z Zheng, SI Amran, PE Thompson, IG Jennings
Molecular pharmacology 80 (4), 657-664, 2011
|Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis|
Z Zheng, SI Amran, J Zhu, O Schmidt-Kittler, KW Kinzler, B Vogelstein, ...
Biochemical Journal 444 (3), 529-535, 2012
|Potent Inhibitors of Phosphatidylinositol 3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms|
NJ O'Brien, S Amran, J Medan, B Cleary, LW Deady, IG Jennings, ...
ChemMedChem 8 (6), 914-918, 2013
|Biochemical and cellular studies of PI3 kinase inhibition|
Monash University. Faculty of Pharmacy and Pharmaceutical Sciences …, 2015
|Mutagenesis of Specific Non-conserved Residues on PI3K for the Discovery of Isoform-selective PI3K Inhibitors|
Monash University, 2008