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Siddharth Balachandran
Siddharth Balachandran
Fox Chase Cancer Center
Verified email at fccc.edu
Title
Cited by
Cited by
Year
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection
S Balachandran, PC Roberts, LE Brown, H Truong, AK Pattnaik, ...
Immunity 13 (1), 129-141, 2000
6462000
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes
N Grandvaux, MJ Servant, B tenOever, GC Sen, S Balachandran, ...
Journal of virology 76 (11), 5532-5539, 2002
5392002
Activation of the dsRNA‐dependent protein kinase, PKR, induces apoptosis through FADD‐mediated death signaling
S Balachandran, CN Kim, WC Yeh, TW Mak, K Bhalla, GN Barber
The EMBO journal, 1998
4871998
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway
S Balachandran, PC Roberts, T Kipperman, KN Bhalla, RW Compans, ...
Journal of virology 74 (3), 1513-1523, 2000
3992000
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases
RJ Thapa, S Nogusa, P Chen, JL Maki, A Lerro, M Andrake, GF Rall, ...
Proceedings of the National Academy of Sciences 110 (33), E3109-E3118, 2013
3662013
A FADD-dependent innate immune mechanism in mammalian cells
S Balachandran, E Thomas, GN Barber
Nature 432 (7015), 401-405, 2004
3622004
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ...
Nature communications 11 (1), 4938, 2020
3442020
DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death
RJ Thapa, JP Ingram, KB Ragan, S Nogusa, DF Boyd, AA Benitez, ...
Cell host & microbe 20 (5), 674-681, 2016
3432016
RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus
S Nogusa, RJ Thapa, CP Dillon, S Liedmann, TH Oguin, JP Ingram, ...
Cell host & microbe 20 (1), 13-24, 2016
3412016
Influenza virus Z-RNAs induce ZBP1-mediated necroptosis
T Zhang, C Yin, DF Boyd, G Quarato, JP Ingram, M Shubina, KB Ragan, ...
Cell 180 (6), 1115-1129. e13, 2020
3102020
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
WJ Kaiser, LP Daley-Bauer, RJ Thapa, P Mandal, SB Berger, C Huang, ...
Proceedings of the National Academy of Sciences 111 (21), 7753-7758, 2014
3042014
RIPK1 and RIPK3 kinases promote cell-death-independent inflammation by toll-like receptor 4
M Najjar, D Saleh, M Zelic, S Nogusa, S Shah, A Tai, JN Finger, ...
Immunity 45 (1), 46-59, 2016
2762016
Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis
S Balachandran, M Porosnicu, GN Barber
Journal of virology 75 (7), 3474-3479, 2001
2472001
Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells
D Olagnier, S Peri, C Steel, N van Montfoort, C Chiang, V Beljanski, ...
PLoS pathogens 10 (12), e1004566, 2014
2462014
Defective translational control facilitates vesicular stomatitis virus oncolysis
S Balachandran, GN Barber
Cancer cell 5 (1), 51-65, 2004
2292004
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming
D Olagnier, AM Brandtoft, C Gunderstofte, NL Villadsen, C Krapp, ...
Nature communications 9 (1), 3506, 2018
2152018
Vesicular stomatitis virus (VSV) therapy of tumors
S Balachandran, GN Barber
IUBMB life 50 (2), 135-138, 2000
2132000
The IRF-3 transcription factor mediates Sendai virus-induced apoptosis
C Heylbroeck, S Balachandran, MJ Servant, C DeLuca, GN Barber, R Lin, ...
Journal of virology 74 (8), 3781-3792, 2000
1982000
Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent …
A Pataer, SA Vorburger, GN Barber, S Chada, AM Mhashilkar, ...
Cancer research 62 (8), 2239-2243, 2002
1872002
NF-κB RelA subunit is crucial for early IFN-β expression and resistance to RNA virus replication
J Wang, SH Basagoudanavar, X Wang, E Hopewell, R Albrecht, ...
The Journal of Immunology 185 (3), 1720-1729, 2010
1702010
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