| Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion N Ishiyama, SH Lee, S Liu, GY Li, MJ Smith, LF Reichardt, M Ikura Cell 141 (1), 117-128, 2010 | 413 | 2010 |
| Inhibition of RAS function through targeting an allosteric regulatory site R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ... Nature chemical biology 13 (1), 62-68, 2017 | 289 | 2017 |
| NMR-based functional profiling of RASopathies and oncogenic RAS mutations MJ Smith, BG Neel, M Ikura Proceedings of the National Academy of Sciences 110 (12), 4574-4579, 2013 | 281 | 2013 |
| Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site MT Mazhab-Jafari, CB Marshall, MJ Smith, GMC Gasmi-Seabrook, ... Proceedings of the National Academy of Sciences 112 (21), 6625-6630, 2015 | 213 | 2015 |
| Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays MJ Smith, WR Hardy, JM Murphy, N Jones, T Pawson Molecular and cellular biology 26 (22), 8461-8474, 2006 | 139 | 2006 |
| Integrated RAS signaling defined by parallel NMR detection of effectors and regulators MJ Smith, M Ikura Nature chemical biology 10 (3), 223-230, 2014 | 96 | 2014 |
| FF domains of CA150 bind transcription and splicing factors through multiple weak interactions MJ Smith, S Kulkarni, T Pawson Molecular and cellular biology, 2004 | 83 | 2004 |
| Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase N Jones, WR Hardy, MB Friese, C Jorgensen, MJ Smith, NM Woody, ... Molecular and cellular biology, 2007 | 82 | 2007 |
| Real-time NMR monitoring of biological activities in complex physiological environments MJ Smith, CB Marshall, FX Theillet, A Binolfi, P Selenko, M Ikura Current opinion in structural biology 32, 39-47, 2015 | 72 | 2015 |
| Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate GM Findlay, MJ Smith, F Lanner, MS Hsiung, GD Gish, E Petsalaki, ... Cell 152 (5), 1008-1020, 2013 | 71 | 2013 |
| Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts CB Marshall, D Meiri, MJ Smith, MT Mazhab-Jafari, ... Methods 57 (4), 473-485, 2012 | 54 | 2012 |
| Real-time NMR study of three small GTPases reveals that fluorescent 2′(3′)-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics MT Mazhab-Jafari, CB Marshall, M Smith, GMC Gasmi-Seabrook, ... Journal of Biological Chemistry 285 (8), 5132-5136, 2010 | 54 | 2010 |
| A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues D Long, CB Marshall, G Bouvignies, MT Mazhab‐Jafari, MJ Smith, M Ikura, ... Angewandte Chemie 125 (41), 10971-10974, 2013 | 50 | 2013 |
| Structure of the DOCK2− ELMO1 complex provides insights into regulation of the auto-inhibited state L Chang, J Yang, CH Jo, A Boland, Z Zhang, SH McLaughlin, ... Nature communications 11 (1), 3464, 2020 | 48 | 2020 |
| Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel RC Killoran, MJ Smith Journal of Biological Chemistry 294 (25), 9937-9948, 2019 | 45 | 2019 |
| The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1 MJ Smith, WR Hardy, GY Li, M Goudreault, S Hersch, P Metalnikov, ... The EMBO Journal 29 (5), 884-896, 2010 | 33 | 2010 |
| Evolution of AF6-RAS association and its implications in mixed-lineage leukemia MJ Smith, E Ottoni, N Ishiyama, M Goudreault, A Haman, C Meyer, ... Nature Communications 8 (1), 1099, 2017 | 31 | 2017 |
| RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway T Dhanaraman, S Singh, RC Killoran, A Singh, X Xu, JM Shifman, ... Science Signaling 13 (653), eabb4778, 2020 | 28 | 2020 |
| Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival TK Lundgren, RP Scott, M Smith, T Pawson, P Ernfors Journal of Biological Chemistry 281 (40), 29886-29896, 2006 | 23 | 2006 |
| Biochemical classification of disease-associated mutants of RAS-like protein expressed in many tissues (RIT1) Z Fang, CB Marshall, JC Yin, MT Mazhab-Jafari, GMC Gasmi-Seabrook, ... Journal of Biological Chemistry 291 (30), 15641-15652, 2016 | 22 | 2016 |
