SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling L Miorin, T Kehrer, MT Sanchez-Aparicio, K Zhang, P Cohen, RS Patel, ... Proceedings of the National Academy of Sciences 117 (45), 28344-28354, 2020 | 475 | 2020 |
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection S Aguirre, P Luthra, MT Sanchez-Aparicio, AM Maestre, J Patel, ... Nature microbiology 2 (5), 1-11, 2017 | 363 | 2017 |
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors GA Versteeg, R Rajsbaum, MT Sánchez-Aparicio, AM Maestre, ... Immunity 38 (2), 384-398, 2013 | 332 | 2013 |
MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection J Canton, AR Fehr, R Fernandez-Delgado, FJ Gutierrez-Alvarez, ... PLoS pathogens 14 (1), e1006838, 2018 | 135 | 2018 |
Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses FW Santiago, LM Covaleda, MT Sanchez-Aparicio, JA Silvas, ... Journal of virology 88 (8), 4572-4585, 2014 | 127 | 2014 |
Subcellular localizations of RIG-I, TRIM25, and MAVS complexes MT Sanchez-Aparicio, J Ayllon, A Leo-Macias, T Wolff, A Garcia-Sastre Journal of virology 91 (2), 2017 | 97 | 2017 |
HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells D Oudshoorn, S van Boheemen, MT Sanchez-Aparicio, R Rajsbaum, ... PloS one 7 (1), e29870, 2012 | 95 | 2012 |
Paramyxovirus V proteins interact with the RIG-I/TRIM25 regulatory complex and inhibit RIG-I signaling MT Sánchez-Aparicio, LJ Feinman, A García-Sastre, ML Shaw Journal of Virology 92 (6), 2018 | 82 | 2018 |
Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing Ebola virus immune evasion P Luthra, S Aguirre, BC Yen, CA Pietzsch, MT Sanchez-Aparicio, ... MBio 8 (2), 2017 | 72 | 2017 |
The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA D Riegger, R Hai, D Dornfeld, B Mänz, V Leyva-Grado, ... Journal of virology 89 (4), 2241-2252, 2015 | 70 | 2015 |
RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection M Schmolke, JR Patel, E de Castro, MT Sánchez-Aparicio, MB Uccellini, ... MBio 5 (2), 2014 | 65 | 2014 |
The therapeutic effect of death: Newcastle disease virus and its antitumor potential S Cuadrado-Castano, MT Sanchez-Aparicio, A García-Sastre, E Villar Virus research 209, 56-66, 2015 | 59 | 2015 |
Structural basis for STAT2 suppression by flavivirus NS5 B Wang, S Thurmond, K Zhou, MT Sánchez-Aparicio, J Fang, J Lu, L Gao, ... Nature Structural & Molecular Biology 27 (10), 875-885, 2020 | 52 | 2020 |
Structure and dynamics of the second CARD of human RIG-I provide mechanistic insights into regulation of RIG-I activation F Ferrage, K Dutta, E Nistal-Villán, JR Patel, MT Sánchez-Aparicio, ... Structure 20 (12), 2048-2061, 2012 | 49 | 2012 |
Influenza virus infection causes global RNAPII termination defects N Zhao, V Sebastiano, N Moshkina, N Mena, J Hultquist, ... Nature Structural & Molecular Biology 25 (9), 885-893, 2018 | 48 | 2018 |
Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus MR Pulido, MT Sánchez-Aparicio, E Martínez-Salas, A García-Sastre, ... PLoS pathogens 14 (6), e1007135, 2018 | 42 | 2018 |
Passenger mutations confound phenotypes of SARM1-deficient mice MB Uccellini, SV Bardina, MT Sánchez-Aparicio, KM White, YJ Hou, ... Cell reports 31 (1), 107498, 2020 | 37 | 2020 |
Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation S Soonthornvacharin, A Rodriguez-Frandsen, Y Zhou, F Galvez, ... Nature microbiology 2 (5), 1-13, 2017 | 32 | 2017 |
Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition C Ferrer-Orta, I de la Higuera, F Caridi, MT Sánchez-Aparicio, E Moreno, ... Journal of virology 89 (13), 6848-6859, 2015 | 32 | 2015 |
Loss of Sendai virus C protein leads to accumulation of RIG-I immunostimulatory defective interfering RNA MT Sánchez-Aparicio, D Garcin, CM Rice, D Kolakofsky, A García-Sastre, ... The Journal of general virology 98 (6), 1282, 2017 | 27 | 2017 |