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Janendra Batra
Janendra Batra
ICMR-National Institute of Pathology, New Delhi
Verified email at nii.ac.in
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A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunotoxins.
VK Chaudhary, JK Batra, MG Gallo, MC Willingham, DJ FitzGerald, ...
Proceedings of the National Academy of Sciences 87 (3), 1066-1070, 1990
3621990
Direct correlation between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and-resistant P388 leukemia cell lines
AM Deffie, JK Batra, GJ Goldenberg
Cancer research 49 (1), 58-62, 1989
3441989
Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin …
AM Deffie, T Alam, C Seneviratne, SW Beenken, JK Batra, TC Shea, ...
Cancer Research 48 (13), 3595-3602, 1988
2561988
Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin.
JK Batra, PG Kasprzyk, RE Bird, I Pastan, CR King
Proceedings of the National Academy of Sciences 89 (13), 5867-5871, 1992
2111992
Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium
K Chang, LH Pai, JK Batra, I Pastan, MC Willingham
Cancer research 52 (1), 181-186, 1992
1921992
Anti-Tac (Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells.
JK Batra, D FitzGerald, M Gately, VK Chaudhary, I Pastan
Journal of Biological Chemistry 265 (25), 15198-15202, 1990
1541990
Single-Chain Immunotoxins Directed at the Human Transferrin Receptor Containing Pseudomonas Exotoxin A or Diphtheria Toxin: Anti-TFR(Fv)-PE40 and DT388 …
JK Batra, DJ Fitzgerald, VK Chaudhary, I Pastan
Molecular and cellular biology 11 (4), 2200-2205, 1991
1441991
Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.
JK Batra, Y Jinno, VK Chaudhary, T Kondo, MC Willingham, DJ FitzGerald, ...
Proceedings of the National Academy of Sciences 86 (21), 8545-8549, 1989
1081989
The cytotoxic activity of ribosome-inactivating protein saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities
S Bagga, D Seth, JK Batra
Journal of Biological Chemistry 278 (7), 4813-4820, 2003
1072003
Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin.
LH Pai, JK Batra, DJ FitzGerald, MC Willingham, I Pastan
Proceedings of the National Academy of Sciences 88 (8), 3358-3362, 1991
1071991
Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds
RJ Kreitman, JK Batra, S Seetharam, VK Chaudhary, DJ FitzGerald, ...
Bioconjugate chemistry 4 (2), 112-120, 1993
1001993
Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor: generation of inhibitor-resistant cytotoxic variants
D Gaur, S Swaminathan, JK Batra
Journal of Biological Chemistry 276 (27), 24978-24984, 2001
872001
Antimicrobial activity of human eosinophil granule proteins: involvement in host defence against pathogens
A Malik, JK Batra
Critical reviews in microbiology 38 (2), 168-181, 2012
802012
Ribosome inactivating protein saporin induces apoptosis through mitochondrial cascade, independent of translation inhibition
D Sikriwal, P Ghosh, JK Batra
The International Journal of Biochemistry & Cell Biology 40 (12), 2880-2888, 2008
782008
Inclusion of a furin-sensitive spacer enhances the cytotoxicity of ribotoxin restrictocin containing recombinant single-chain immunotoxins
A Goyal, JK Batra
Biochemical Journal 345 (2), 247-254, 2000
662000
Mycobacterium tuberculosis ClpC1: Characterization and role of the N‐terminal domain in its function
NP Kar, D Sikriwal, P Rath, RK Choudhary, JK Batra
The FEBS journal 275 (24), 6149-6158, 2008
562008
Structure-function studies with derivatives of 6-benzyl-1, 3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.
JK Batra, L Jurd, E Hamel
Molecular pharmacology 27 (1), 94-102, 1985
541985
Expression of ribonucleolytic toxin restrictocin in Escherichia coli: purification and characterization
D Rathore, SK Nayak, JK Batra
FEBS letters 392 (3), 259-262, 1996
521996
Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin
I Pastan, V Chaudhary, D FitzGerald, J Batra
US Patent 6,099,842, 2000
502000
Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys
LH Pai, JK Batra, DJ FitzGerald, MC Willingham, I Pastan
Cancer research 52 (11), 3189-3193, 1992
471992
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