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E. John Wherry
E. John Wherry
Verified email at pennmedicine.upenn.edu - Homepage
Title
Cited by
Cited by
Year
Restoring function in exhausted CD8 T cells during chronic viral infection
DL Barber, EJ Wherry, D Masopust, B Zhu, JP Allison, AH Sharpe, ...
Nature 439 (7077), 682-687, 2006
50402006
T cell exhaustion
EJ Wherry
Nature immunology 12 (6), 492-499, 2011
46202011
Molecular and cellular insights into T cell exhaustion
EJ Wherry, M Kurachi
Nature reviews immunology 15 (8), 486-499, 2015
43672015
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
CL Day, DE Kaufmann, P Kiepiela, JA Brown, ES Moodley, S Reddy, ...
Nature 443 (7109), 350-354, 2006
33222006
Effector and memory T-cell differentiation: implications for vaccine development
SM Kaech, EJ Wherry, R Ahmed
Nature Reviews Immunology 2 (4), 251-262, 2002
24702002
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
EJ Wherry, SJ Ha, SM Kaech, WN Haining, S Sarkar, V Kalia, ...
Immunity 27 (4), 670-684, 2007
24692007
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
SD Blackburn, H Shin, WN Haining, T Zou, CJ Workman, A Polley, ...
Nature immunology 10 (1), 29-37, 2009
24532009
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
C Twyman-Saint Victor, AJ Rech, A Maity, R Rengan, KE Pauken, ...
Nature 520 (7547), 373-377, 2015
24472015
Lineage relationship and protective immunity of memory CD8 T cell subsets
EJ Wherry, V Teichgräber, TC Becker, D Masopust, SM Kaech, R Antia, ...
Nature immunology 4 (3), 225-234, 2003
23972003
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
G Chen, AC Huang, W Zhang, G Zhang, M Wu, W Xu, Z Yu, J Yang, ...
Nature 560 (7718), 382-386, 2018
23652018
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
SM Kaech, JT Tan, EJ Wherry, BT Konieczny, CD Surh, R Ahmed
Nature immunology 4 (12), 1191-1198, 2003
23492003
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
EJ Wherry, JN Blattman, K Murali-Krishna, R Van Der Most, R Ahmed
Journal of virology 77 (8), 4911-4927, 2003
20072003
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
AH Sharpe, EJ Wherry, R Ahmed, GJ Freeman
Nature immunology 8 (3), 239-245, 2007
19142007
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
LA Monticelli, GF Sonnenberg, MC Abt, T Alenghat, CGK Ziegler, ...
Nature immunology 12 (11), 1045-1054, 2011
16912011
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ...
Science 369 (6508), eabc8511, 2020
16412020
CD8 T cell exhaustion during chronic viral infection and cancer
LM McLane, MS Abdel-Hakeem, EJ Wherry
Annual review of immunology 37 (1), 457-495, 2019
16232019
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ...
Nature 545 (7652), 60-65, 2017
15892017
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ...
Nature medicine 24 (5), 563-571, 2018
15302018
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
AM Intlekofer, N Takemoto, EJ Wherry, SA Longworth, JT Northrup, ...
Nature immunology 6 (12), 1236-1244, 2005
15092005
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
O Khan, JR Giles, S McDonald, S Manne, SF Ngiow, KP Patel, MT Werner, ...
Nature 571 (7764), 211-218, 2019
12942019
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