Tracey Gloster
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Recent structural insights into the expanding world of carbohydrate-active enzymes
GJ Davies, TM Gloster, B Henrissat
Current opinion in structural biology 15 (6), 637-645, 2005
Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells
TM Gloster, WF Zandberg, JE Heinonen, DL Shen, L Deng, DJ Vocadlo
Nature chemical biology 7 (3), 174-181, 2011
Glycosidase inhibition: assessing mimicry of the transition state
TM Gloster, GJ Davies
Organic & biomolecular chemistry 8 (2), 305-320, 2010
Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology
TM Gloster, DJ Vocadlo
Nature chemical biology 8 (8), 683-694, 2012
Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to β-glucosidases
DL Zechel, AB Boraston, T Gloster, CM Boraston, JM Macdonald, ...
Journal of the American Chemical Society 125 (47), 14313-14323, 2003
The mechanisms by which family 10 glycoside hydrolases bind decorated substrates
G Pell, EJ Taylor, TM Gloster, JP Turkenburg, CMGA Fontes, LMA Ferreira, ...
Journal of Biological Chemistry 279 (10), 9597-9605, 2004
Advances in understanding glycosyltransferases from a structural perspective
TM Gloster
Current opinion in structural biology 28, 131-141, 2014
Structural snapshots of the reaction coordinate for O-GlcNAc transferase
MB Lazarus, J Jiang, TM Gloster, WF Zandberg, GE Whitworth, ...
Nature chemical biology 8 (12), 966-968, 2012
Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics
TM Gloster, P Meloncelli, RV Stick, D Zechel, A Vasella, GJ Davies
Journal of the American Chemical Society 129 (8), 2345-2354, 2007
An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
JS Athukoralage, SA McMahon, C Zhang, S Grüschow, S Graham, ...
Nature 577 (7791), 572-575, 2020
Characterization and three-dimensional structures of two distinct bacterial xyloglucanases from families GH5 and GH12
TM Gloster, FM Ibatullin, K Macauley, JM Eklof, S Roberts, JP Turkenburg, ...
Journal of Biological Chemistry 282 (26), 19177-19189, 2007
Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function
C Montanier, AL Van Bueren, C Dumon, JE Flint, MA Correia, JA Prates, ...
Proceedings of the National Academy of Sciences 106 (9), 3065-3070, 2009
How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity
F Cuskin, JE Flint, TM Gloster, C Morland, A Baslé, B Henrissat, ...
Proceedings of the National Academy of Sciences 109 (51), 20889-20894, 2012
Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases
EJ Taylor, TM Gloster, JP Turkenburg, F Vincent, AM Brzozowski, ...
Journal of Biological Chemistry 281 (16), 10968-10975, 2006
Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors
RP Gibson, TM Gloster, S Roberts, RAJ Warren, I Storch de Gracia, ...
Angewandte Chemie International Edition 46 (22), 4115-4119, 2007
Divergence of catalytic mechanism within a glycosidase family provides insight into evolution of carbohydrate metabolism by human gut flora
TM Gloster, JP Turkenburg, JR Potts, B Henrissat, GJ Davies
Chemistry & biology 15 (10), 1058-1067, 2008
Structural and Biochemical Analysis of Cellvibrio japonicus Xylanase 10C: HOW VARIATION IN SUBSTRATE-BINDING CLEFT INFLUENCES THE CATALYTIC PROFILE OF FAMILY GH-10 XYLANASES*[boxs]
G Pell, L Szabo, SJ Charnock, H Xie, TM Gloster, GJ Davies, HJ Gilbert
Journal of Biological Chemistry 279 (12), 11777-11788, 2004
Total Syntheses of Casuarine and Its 6‐O‐α‐Glucoside: Complementary Inhibition towards Glycoside Hydrolases of the GH31 and GH37 Families
F Cardona, C Parmeggiani, E Faggi, C Bonaccini, P Gratteri, L Sim, ...
Chemistry–A European Journal 15 (7), 1627-1636, 2009
Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate
SA McMahon, W Zhu, S Graham, R Rambo, MF White, TM Gloster
Nature communications 11 (1), 500, 2020
Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes
MS Macauley, Y He, TM Gloster, KA Stubbs, GJ Davies, DJ Vocadlo
Chemistry & biology 17 (9), 937-948, 2010
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