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Hiwa K. Saeed
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Multimodal super-resolution optical microscopy using a transition-metal-based probe provides unprecedented capabilities for imaging both nuclear chromatin and mitochondria
S Sreedharan, MR Gill, E Garcia, HK Saeed, D Robinson, A Byrne, ...
Journal of the American Chemical Society 139 (44), 15907-15913, 2017
762017
Exploring the cytotoxicity, uptake, cellular response, and proteomics of mono-and dinuclear DNA light-switch complexes
PJ Jarman, F Noakes, S Fairbanks, K Smitten, IK Griffiths, HK Saeed, ...
Journal of the American Chemical Society 141 (7), 2925-2937, 2018
562018
A super-resolution probe to monitor HNO levels in the endoplasmic reticulum of cells
F Ali, S Sreedharan, AH Ashoka, HK Saeed, CGW Smythe, JA Thomas, ...
Analytical chemistry 89 (22), 12087-12093, 2017
56*2017
Photoactive metal complexes that bind DNA and other biomolecules as cell probes, therapeutics, and theranostics
HK Saeed, S Sreedharan, JA Thomas
Chemical communications 56 (10), 1464-1480, 2020
362020
Making the Right Link to Theranostics: The Photophysical and Biological Properties of Dinuclear RuII–ReI dppz Complexes Depend on Their Tether
HK Saeed, S Sreedharan, PJ Jarman, SA Archer, SD Fairbanks, ...
Journal of the American Chemical Society 142 (2), 1101-1111, 2019
362019
Homo‐ and Heteroleptic Phototoxic Dinuclear Metallo‐Intercalators Based on RuII(dppn) Intercalating Moieties: Synthesis, Optical, and Biological Studies
HK Saeed, PJ Jarman, S Archer, S Sreedharan, IQ Saeed, LK Mckenzie, ...
Angewandte Chemie International Edition 56 (41), 12628-12633, 2017
362017
A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium (II) metallo-intercalator
MR Gill, PJ Jarman, S Halder, MG Walker, HK Saeed, JA Thomas, ...
Chemical Science 9 (4), 841-849, 2018
352018
Tracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe
F Ali, S Aute, S Sreedharan, HA Anila, HK Saeed, CG Smythe, JA Thomas, ...
Chemical communications 54 (15), 1849-1852, 2018
332018
The Structure of Linkers Affects the DNA Binding Properties of Tethered Dinuclear Ruthenium (II) Metallo‐Intercalators
HK Saeed, IQ Saeed, NJ Buurma, JA Thomas
Chemistry–A European Journal 23 (23), 5467-5477, 2017
202017
Synthesis and characterization of lipophilic salts of metformin to improve its repurposing for cancer therapy
HK Saeed, Y Sutar, P Patel, R Bhat, S Mallick, AE Hatada, DLT Koomoa, ...
ACS omega 6 (4), 2626-2637, 2021
152021
In vitro efficacy of anthelmintics on Angiostrongylus cantonensis L3 larvae
J Jacob, G Tan, I Lange, H Saeed, A Date, S Jarvi
Parasitology, 1-11, 2020
152020
Docusate-based ionic liquids of anthelmintic benzimidazoles show improved pharmaceutical processability, lipid solubility, and in vitro activity against cryptococcus neoformans
Y Sutar, SR Fulton, S Paul, S Altamirano, S Mhatre, H Saeed, P Patel, ...
ACS infectious diseases 7 (9), 2637-2649, 2021
112021
An ion‐paired moxifloxacin nanosuspension eye drop provides improved prevention and treatment of ocular infection
A Josyula, R Omiadze, K Parikh, P Kanvinde, MB Appell, P Patel, ...
Bioengineering & Translational Medicine, 2021
102021
Inside Cover: The Structure of Linkers Affects the DNA Binding Properties of Tethered Dinuclear Ruthenium (II) Metallo‐Intercalators (Chem. Eur. J. 23/2017)
HK Saeed, IQ Saeed, NJ Buurma, JA Thomas
Chemistry–A European Journal 23 (23), 5389-5389, 2017
22017
Correction to “Shifting the Antibody–Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy against Human Epidermal Growth Factor Receptor 2 …
A Ahad, HK Saeed, V Del Solar, JE López-Hernández, A Michel, ...
ACS Pharmacology & Translational Science 7 (1), 298-299, 2024
2024
Shifting the Antibody–Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy against Human Epidermal Growth Factor Receptor 2-Positive Breast …
A Ahad, H K. Saeed, V Del Solar, JE López-Hernández, A Michel, ...
ACS Pharmacology & Translational Science 6 (12), 1972-1986, 2023
2023
From chemotherapy to phototherapy-changing the therapeutic action of a metallo-intercalating RuII-ReI luminescent system by switching its sub-cellular location
H Saeed, PJ Jarman, S Sreedharan, R Mowll, AJ Auty, A Ap Chauvet, ...
Chemistry (Weinheim an der Bergstrasse, Germany), e202300617, 2023
2023
Making the Right Link to Theranostics: The Photophysical and Biological Properties of Dinuclear Ruᴵᴵ–Reᴵ dppz Complexes Depend on Their Tether
HK Saeed, S Sreedharan, PJ Jarman, SA Archer, SD Fairbanks, ...
Journal of the American Chemical Society 142 (2), 2019
2019
PhD thesis 'Biophysical studies on dinuclear DNA metallo-intercalators containing the ruthenium (II) tris (1-pyrazolyl) methane unit'
H Saeed
University of Sheffield, 2016
2016
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Articles 1–19